Publications by authors named "Jacques Genest"

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Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease.
Paul M Ridker, Brendan M Everett, Tom Thuren, Jean G MacFadyen, William H Chang, Christie Ballantyne, Francisco Fonseca, Jose Nicolau, Wolfgang Koenig, Stefan D Anker

N Engl J Med· September 2017

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Isolated aerobic exercise and weight loss: a systematic review and meta-analysis of randomized controlled trials.
Adrian Thorogood, Salvatore Mottillo, Avi Shimony, Kristian B Filion, Lawrence Joseph, Jacques Genest, Louise Pilote, Paul Poirier, Ernesto L Schiffrin, Mark J Eisenberg

Am J Med· August 2011

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The metabolic syndrome and cardiovascular risk a systematic review and meta-analysis.
Salvatore Mottillo, Kristian B Filion, Jacques Genest, Lawrence Joseph, Louise Pilote, Paul Poirier, Stéphane Rinfret, Ernesto L Schiffrin, Mark J Eisenberg

September 2010

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Rosuvastatin to prevent vascular events in men and women with elevated C-reactive protein.
Paul M Ridker, Eleanor Danielson, Francisco A H Fonseca, Jacques Genest, Antonio M Gotto, John J P Kastelein, Wolfgang Koenig, Peter Libby, Alberto J Lorenzatti, Jean G MacFadyen

November 2008

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Imputation of untreated LDL-C in treated subjects with homozygous familial hypercholesterolaemia: An international collaboration.
G B John Mancini, Arnold Ryomoto, Isabelle Ruel, Iulia Iatan, Frederick J Raal, Jacques Genest

Atherosclerosis· January 2026

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Polygenic risk score for coronary artery disease predicts atherosclerotic cardiovascular disease in familial hypercholesterolemia.
Martine Paquette, Mark Trinder, Isabelle Ruel, Simon-Pierre Guay, Robert A Hegele, Jacques Genest

J Clin Lipidol· June 2025

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Extreme LDL-C concentration is associated with increased cardiovascular disease in women with homozygous familial hypercholesterolemia.
Martine Paquette, Isabelle Ruel, Simon-Pierre Guay, Zobaida Al-Baldawi, Diane Brisson, Jacques Genest

J Clin Lipidol· April 2025

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Low-Dose Docetaxel Is Effective in Reducing Atherogenic Lipids and Atherosclerosis.
Hong Y Choi, Isabelle Ruel, Shiwon Choi, Iulia Iatan, Senna Choi, Jacques Genest

Int J Mol Sci· February 2025

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Prevention and Management of Cardiovascular Disease in Primary Care: A Comment on the PEER Simplified Lipid Guideline.
G B John Mancini, Glen J Pearson, Arden R Barry, Patrick Couture, Natalie Dayan, Jacques Genest

CJC Open· October 2024

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Sex differences in treatment of familial hypercholesterolaemia: a meta-analysis.
Iulia Iatan, Leo E Akioyamen, Isabelle Ruel, Amanda Guerin, Lindsay Hales, Jacques Genest

Eur Heart J· September 2024

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Influence of Polygenic Background on the Clinical Presentation of Familial Hypercholesterolemia.
Mark Trinder, Lubomira Cermakova, Isabelle Ruel, Alexis Baass, Martine Paquette, Jacques Genest

Arterioscler Thromb Vasc Biol· July 2024

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Sex differences in the presentation, treatment and outcomes of patients with homozygous familial hypercholesterolemia.
Zobaida Al-Baldawi, Leslie Brown, Isabelle Ruel, Alexis Baass, Jean Bergeron, Jacques Genest

J Clin Lipidol· May 2024

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Sex differences in the perception of cardiovascular risk in familial hypercholesterolemia.
Balaqis Alshibani, Iulia Iatan, Amanda Guerin, Isabelle Ruel, Lubomira Cermakova, Jacques Genest

J Clin Lipidol· March 2024

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Meta-Analysis of Randomized Trials: Efficacy and Safety of Colchicine for Secondary Prevention of Cardiovascular Disease.
Elie Akl, Nazanin Sahami, Christopher Labos, Jacques Genest, Ali Zgheib

J Interv Cardiol· March 2024

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Significance of the Wnt signaling pathway in coronary artery atherosclerosis.
Kashif Khan, Bin Yu, Jean-Claude Tardif, Eric Rhéaume, Hamood Al-Kindi, Jacques Genest

Front Cardiovasc Med· March 2024

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Increased FH-Risk-Score and Diabetes Are Cardiovascular Risk Equivalents in Heterozygous Familial Hypercholesterolemia.
Martine Paquette, Bertrand Cariou, Sophie Bernard, Robert A Hegele, Antonio Gallo, Jacques Genest

Arterioscler Thromb Vasc Biol· February 2024

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Genetic testing for familial hypercholesterolemia in Quebec, Canada: a single-centre retrospective cohort study.
Amanda Guerin, Iulia Iatan, Isabelle Ruel, Linda Fri Ngufor, Jacques Genest

CMAJ Open· August 2023

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Metabolic syndrome predicts cardiovascular risk and mortality in familial hypercholesterolemia.
Martine Paquette, Sophie Bernard, Bertrand Cariou, Robert A Hegele, Jacques Genest

J Clin Lipidol· June 2023

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Docetaxel as a Model Compound to Promote HDL (High-Density Lipoprotein) Biogenesis and Reduce Atherosclerosis.
Hong Y Choi, Iulia Iatan, Isabelle Ruel, Leslie Brown, Lindsay Hales, Jacques Genest

Arterioscler Thromb Vasc Biol· May 2023

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Homozygous Familial Hypercholesterolemia in Canada: An Observational Study.
Leslie Brown, Isabelle Ruel, Alexis Baass, Jean Bergeron, Liam R Brunham, Jacques Genest

JACC Adv· May 2023

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Estimating the Prevalence of Hypercholesterolemia in Indigenous Populations: A Systematic Review and Meta-Analysis.
Rylan K McCallum, Adam I Kramer, Miles Marchand, Leo E Akioyamen, Jacques Genest

JACC Adv· May 2023

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Transient very low LDL-C levels: a legacy effect for cardiovascular prevention?
Jacques Genest

Eur Heart J· April 2023

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Biomedical Advances in ABCA1 Transporter: From Bench to Bedside.
Hong Y Choi, Senna Choi, Iulia Iatan, Isabelle Ruel, Jacques Genest

Biomedicines· February 2023

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Effect of the LDL receptor mutation type on incident major adverse cardiovascular events in familial hypercholesterolaemia.
Martine Paquette, Alain Carrié, Sophie Bernard, Bertrand Cariou, Robert A Hegele, Jacques Genest

Eur J Prev Cardiol· November 2022

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Recurrent acute coronary syndrome caused by a primary aortic valve sarcoma: grand rounds and literature review.
Martine Parent, Kevin Lachapelle, Badia Issa-Chergui, Thierry Alcindor, Jacques Genest

Eur Heart J Case Rep· November 2022

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Aortic stenosis in homozygous familial hypercholesterolaemia: a paradigm shift over a century.
Alexandre M Bélanger, Leo E Akioyamen, Isabelle Ruel, Lindsay Hales, Jacques Genest

Eur Heart J· September 2022

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High-Density Lipoprotein and Cardiovascular Disease-Where do We Stand?
Iulia Iatan, Hong Y Choi, Jacques Genest

Endocrinol Metab Clin North Am· September 2022

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Prevalence and Treatment of Familial Hypercholesterolemia and Severe Hypercholesterolemia in Older Adults in Ontario, Canada.
Leo E Akioyamen, Anna Chu, Jacques Genest, Douglas S Lee, Husam Abdel-Qadir

CJC Open· September 2022

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Macrophage Jak2 deficiency accelerates atherosclerosis through defects in cholesterol efflux.
Idit Dotan, Jiaqi Yang, Jiro Ikeda, Ziv Roth, Evan Pollock-Tahiri, Jacques Genest

Commun Biol· February 2022

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