Publications by authors named "Jae-Sik Shin"

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TP53 and DNA-PK as potential biomarkers for enhanced efficacy of Olaparib in colorectal cancer.
Do Yeon Kim, Hyeseon Yun, Ji-Eun You, Yoon Sun Park, Yea Seong Ryu, Jae-Sik Shin

Invest New Drugs· June 2025

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The Immune Suppressor IGSF1 as a Potential Target for Cancer Immunotherapy.
Dong-In Koh, Minki Lee, Yoon Sun Park, Jae-Sik Shin, Joseph Kim

Cancer Immunol Res· April 2024

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Targeting isoforms of RON kinase (MST1R) drives antitumor efficacy.
Joseph Kim, Dong-In Koh, Minki Lee, Yoon Sun Park, Seung-Woo Hong, Jae-Sik Shin

Cell Death Differ· December 2023

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CJ14939, a Novel JAK Inhibitor, Increases Oxaliplatin-induced Cell Death Through JAK/STAT Pathway in Colorectal Cancer.
Jun Ki Hong, DO Yeon Kim, Jae-Sik Shin, Yea Seong Ryu, Jai-Hee Moon

Anticancer Res· April 2022

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Mutation SVCT2 promotes cell proliferation, invasion and migration in colorectal cancer.
Sang-Soo Park, Yea Seong Ryu, Dong-In Koh, Seung-Woo Hong, Jai-Hee Moon, Jae-Sik Shin, Joo-Yeon Shin

J Cancer· July 2021

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Role of p53 in transcriptional repression of SVCT2.
Eun Ho Kim, Dong-In Koh, Yea Seong Ryu, Sang-Soo Park, Seung-Woo Hong, Jae-Sik Shin, Joo-Yeon Shin

Mol Biol Rep· February 2021

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Chemosensitivity to HM90822, a novel synthetic IAP antagonist, is determined by p-AKT-inducible XIAP phosphorylation in human pancreatic cancer cells.
Seung-Woo Hong, Jae-Sik Shin, Jai-Hee Moon, Soo-A Jung, Dong-In Koh, Jung Shin Lee

Invest New Drugs· December 2020

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Epigenetic regulation of miR-29a/miR-30c/DNMT3A axis controls SOD2 and mitochondrial oxidative stress in human mesenchymal stem cells.
Yi-Deun Jung, Seul-Ki Park, Dayeon Kang, Supyong Hwang, Myoung-Hee Kang, Jae-Sik Shin

Redox Biol· October 2020

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Inhibition of JAK1/2 can overcome EGFR-TKI resistance in human NSCLC.
Dong Min Kim, Mi Jin Kim, Jai-Hee Moon, Eun Young Lee, Jun Ki Hong, Jae-Sik Shin

Biochem Biophys Res Commun· June 2020

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Targeting β-catenin overcomes MEK inhibition resistance in colon cancer with KRAS and PIK3CA mutations.
Jai-Hee Moon, Seung-Woo Hong, Jeong Eun Kim, Jae-Sik Shin, Jin-Sun Kim

Br J Cancer· April 2019

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Human breast cancer cells display different sensitivities to ABT-263 based on the level of survivin.
Eun Young Lee, Eun-Yeung Gong, Jae-Sik Shin, Jai-Hee Moon, Hyun Jae Shim, Jimin Shin

Toxicol In Vitro· February 2018

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SH003 selectively induces p73‑dependent apoptosis in triple‑negative breast cancer cells.
Eun Kyoung Choi, Seung-Mi Kim, Seung-Woo Hong, Jai-Hee Moon, Jae-Sik Shin, Jung Shin Lee

Mol Med Rep· October 2016

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Combined treatment with vitamin C and sulindac synergistically induces p53- and ROS-dependent apoptosis in human colon cancer cells.
Eun-Yeung Gong, Yu Jin Shin, Ih-Yeon Hwang, Jeong Hee Kim, Seung-Mi Kim, Jae-Sik Shin

Toxicol Lett· September 2016

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L-Ascorbic acid can abrogate SVCT-2-dependent cetuximab resistance mediated by mutant KRAS in human colon cancer cells.
Soo-A Jung, Dae-Hee Lee, Jai-Hee Moon, Seung-Woo Hong, Jae-Sik Shin, Yu Jin Shin, Jung Shin Lee

Free Radic Biol Med· June 2016

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SAHA, an HDAC inhibitor, overcomes erlotinib resistance in human pancreatic cancer cells by modulating E-cadherin.
Seong Joon Park, Seung-Mi Kim, Jai-Hee Moon, Jeong Hee Kim, Jae-Sik Shin, Yu Jin Shin, Jung Shin Lee

Tumour Biol· April 2016

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Targeting FGFR Pathway in Human Hepatocellular Carcinoma: Expressing pFGFR and pMET for Antitumor Activity.
Jae-Cheol Jo, Eun Kyoung Choi, Jae-Sik Shin, Jai-Hee Moon, Seung-Woo Hong, Jung Shin Lee

Mol Cancer Ther· November 2015

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A novel small-molecule IAP antagonist, AZD5582, draws Mcl-1 down-regulation for induction of apoptosis through targeting of cIAP1 and XIAP in human pancreatic cancer.
Jai-Hee Moon, Jae-Sik Shin, Seung-Woo Hong, Soo-A Jung, Ih-Yeon Hwang, Jung Shin Lee

Oncotarget· September 2015

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Cellular inhibitor of apoptosis protein 1 (cIAP1) stability contributes to YM155 resistance in human gastric cancer cells.
Soo-A Jung, Yong-Man Park, Seung-Woo Hong, Jai-Hee Moon, Jae-Sik Shin, Jung Shin Lee

J Biol Chem· April 2015

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Surgical Outcome of a Zero-profile Device Comparing with Stand-alone Cage and Anterior Cervical Plate with Iliac Bone Graft in the Anterior Cervical Discectomy and Fusion.
Jae Sik Shin, Sung Han Oh, Pyoung Goo Cho

Korean J Spine· September 2014

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NPS-1034, a novel MET inhibitor, inhibits the activated MET receptor and its constitutively active mutants.
Jae-Sik Shin, Seung-Woo Hong, Jai-Hee Moon, Jin-Sun Kim, Kyung-Ah Jung, Jung Shin Lee

Invest New Drugs· June 2014

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NVP-BEZ235, a dual PI3K/mTOR inhibitor, induces cell death through alternate routes in prostate cancer cells depending on the PTEN genotype.
Seung-Woo Hong, Jae-Sik Shin, Jai-Hee Moon, Ye-Seul Kim, Jooyoung Lee, Jung Shin Lee

Apoptosis· May 2014

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YM155 induces EGFR suppression in pancreatic cancer cells.
Young-Soon Na, Soo-Jin Yang, Seung-Mi Kim, Kyung-Ah Jung, Jai-Hee Moon, Jae-Sik Shin, Jung Shin Lee

PLoS One· December 2012

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Bortezomib induces G2-M arrest in human colon cancer cells through ROS-inducible phosphorylation of ATM-CHK1.
Yong Sang Hong, Seung-Woo Hong, Seung-Mi Kim, Dong-Hoon Jin, Jae-Sik Shin, Jung Shin Lee

Int J Oncol· July 2012

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Ring finger protein 149 is an E3 ubiquitin ligase active on wild-type v-Raf murine sarcoma viral oncogene homolog B1 (BRAF).
Seung-Woo Hong, Dong-Hoon Jin, Jae-Sik Shin, Jai-Hee Moon, Young-Soon Na, Jung Shin Lee

J Biol Chem· July 2012

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The survivin suppressant YM155 potentiates chemosensitivity to gemcitabine in the human pancreatic cancer cell line MiaPaCa-2.
Dok Hyun Yoon, Jae-Sik Shin, Dong-Hoon Jin, Seung-Woo Hong, Kyung A Jung, Jung Shin Lee

Anticancer Res· May 2012

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