Publications by authors named "Jaechan Leem"

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Protective effects and mechanisms of cynaroside on renal fibrosis in mice with unilateral ureteral obstruction.
Ah Young Yang, Jung-Yeon Kim, Mi-Gyeong Gwon, Kiryeong Kim, Hyun Hee Kwon, Jaechan Leem

Redox Rep· December 2025

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Protective Effects of Tormentic Acid on Unilateral Ureteral Obstruction-Induced Renal Injury, Inflammation, and Fibrosis: A Comprehensive Approach to Reducing Oxidative Stress, Apoptosis, and Ferroptosis.
Ah Young Yang, Jung-Yeon Kim, Mi-Gyeong Gwon, Hyun Hee Kwon, Jaechan Leem

Antioxidants (Basel)· December 2024

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Efficacy of Trametinib in Alleviating Cisplatin-Induced Acute Kidney Injury: Inhibition of Inflammation, Oxidative Stress, and Tubular Cell Death in a Mouse Model.
Joung Eun Lee, Jung-Yeon Kim, Jaechan Leem

Molecules· June 2024

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Pharmacological inhibition of p300 ameliorates steatosis, inflammation, and fibrosis in mice with non-alcoholic steatohepatitis.
Jung-Yeon Kim, Ah Young Yang, Kiryeong Kim, Hyun Hee Kwon, Jaechan Leem

Heliyon· May 2024

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Kahweol Inhibits Pro-Inflammatory Cytokines and Chemokines in Tumor Necrosis Factor-α/Interferon-γ-Stimulated Human Keratinocyte HaCaT Cells.
Ye Jin Kwon, Hyun Hee Kwon, Jaechan Leem, Yoon Young Jang

Curr Issues Mol Biol· April 2024

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6-Shogaol Ameliorates Liver Inflammation and Fibrosis in Mice on a Methionine- and Choline-Deficient Diet by Inhibiting Oxidative Stress, Cell Death, and Endoplasmic Reticulum Stress.
Ah Young Yang, Kiryeong Kim, Hyun Hee Kwon, Jaechan Leem, Jeong Eun Song

Molecules· January 2024

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The decoy oligodeoxynucleotide against HIF-1α and STAT5 ameliorates atopic dermatitis-like mouse model.
Mi-Gyeong Gwon, Jaechan Leem, Hyun-Jin An, Hyemin Gu, Seongjae Bae

Mol Ther Nucleic Acids· December 2023

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Eupatilin Ameliorates Lipopolysaccharide-Induced Acute Kidney Injury by Inhibiting Inflammation, Oxidative Stress, and Apoptosis in Mice.
Kiryeong Kim, Hyo-Lim Hong, Gyun Moo Kim, Jaechan Leem, Hyun Hee Kwon

Curr Issues Mol Biol· August 2023

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STAT3/NF‑κB decoy oligodeoxynucleotides inhibit atherosclerosis through regulation of the STAT/NF‑κB signaling pathway in a mouse model of atherosclerosis.
Hyun-Jin An, Mi-Gyeong Gwon, Hyemin Gu, Seongjae Bae, Jaechan Leem

Int J Mol Med· May 2023

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Protective Effects of Apamin on Acetaminophen-Induced Hepatotoxicity in Mice.
Hyo-Jeong Jang, Jaechan Leem, Gyun Moo Kim

Curr Issues Mol Biol· May 2023

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Antioxidant, Antiapoptotic, and Anti-Inflammatory Effects of Hesperetin in a Mouse Model of Lipopolysaccharide-Induced Acute Kidney Injury.
Ah Young Yang, Hye Jin Choi, Kiryeong Kim, Jaechan Leem

Molecules· March 2023

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Antioxidant, Anti-Apoptotic, and Anti-Inflammatory Effects of Farrerol in a Mouse Model of Obstructive Uropathy.
Jung-Yeon Kim, Jaechan Leem, Kwan-Kyu Park

Curr Issues Mol Biol· January 2023

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Protective Effects of Orexin A in a Murine Model of Cisplatin-Induced Acute Kidney Injury.
Jungmin Jo, Jung-Yeon Kim, Jaechan Leem

J Clin Med· December 2022

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Protective Effects of Carnosol on Renal Interstitial Fibrosis in a Murine Model of Unilateral Ureteral Obstruction.
Jae-Hyung Park, Jaechan Leem, Sun-Jae Lee

Antioxidants (Basel)· November 2022

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Synthetic Non-Coding RNA for Suppressing mTOR Translation to Prevent Renal Fibrosis Related to Autophagy in UUO Mouse Model.
Young-Ah Kim, Hyemin Gu, Mi-Gyeong Gwon, Hyun-Jin An, Seongjae Bae, Jaechan Leem

Int J Mol Sci· September 2022

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Therapeutic Effect of Bee Venom and Melittin on Skin Infection Caused by .
Seongjae Bae, Hyemin Gu, Mi-Gyeong Gwon, Hyun-Jin An, Sang-Mi Han, Jaechan Leem

Toxins (Basel)· September 2022

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Kahweol Protects against Acetaminophen-Induced Hepatotoxicity in Mice through Inhibiting Oxidative Stress, Hepatocyte Death, and Inflammation.
Jung-Yeon Kim, Jaechan Leem, Gyun Moo Kim

Biomed Res Int· April 2022

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Oridonin Attenuates Cisplatin-Induced Acute Kidney Injury via Inhibiting Oxidative Stress, Apoptosis, and Inflammation in Mice.
Hyemin Gu, Mi-Gyeong Gwon, Jong Hyun Kim, Jaechan Leem, Sun-Jae Lee

Biomed Res Int· April 2022

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Bee Venom and Its Major Component Melittin Attenuated - and IGF-1-Induced Acne Vulgaris via Inactivation of Akt/mTOR/SREBP Signaling Pathway.
Hyemin Gu, Hyun-Jin An, Mi-Gyeong Gwon, Seongjae Bae, Jaechan Leem

Int J Mol Sci· March 2022

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Hispidulin Ameliorates Endotoxin-Induced Acute Kidney Injury in Mice.
Kiryeong Kim, Jaechan Leem

Molecules· March 2022

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Anti-Fibrotic Effect of Synthetic Noncoding Oligodeoxynucleotide for Inhibiting mTOR and STAT3 via the Regulation of Autophagy in an Animal Model of Renal Injury.
Hyun Jin Jung, Hyun-Jin An, Mi-Gyeong Gwon, Hyemin Gu, Seongjae Bae, Jaechan Leem

Molecules· January 2022

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Protective Effects of Carnosic Acid on Lipopolysaccharide-Induced Acute Kidney Injury in Mice.
Jung-Yeon Kim, Hyo-Lim Hong, Gyun Moo Kim, Jaechan Leem, Hyun Hee Kwon

Molecules· December 2021

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Protective Effects of 6-Shogaol, an Active Compound of Ginger, in a Murine Model of Cisplatin-Induced Acute Kidney Injury.
Mi-Gyeong Gwon, Hyemin Gu, Jaechan Leem, Kwan-Kyu Park

Molecules· September 2021

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Protective Effects of Bee Venom-Derived Phospholipase A against Cholestatic Liver Disease in Mice.
Jung-Yeon Kim, Hyo-Jeong Jang, Jaechan Leem, Gyun-Moo Kim

Biomedicines· August 2021

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Heme Oxygenase-1 Induction by Cobalt Protoporphyrin Ameliorates Cholestatic Liver Disease in a Xenobiotic-Induced Murine Model.
Jung-Yeon Kim, Yongmin Choi, Jaechan Leem, Jeong Eun Song

Int J Mol Sci· July 2021

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