Publications by authors named "Jaewon Ko"

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MDGAs as synaptic suppressors with implications in neurodevelopmental disorders.
Jaewon Ko

Curr Opin Neurobiol· December 2025

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Paralogs of Slitrk cell adhesion molecules configure excitatory synapse specificity via distinct cellular mechanisms.
Dongwook Kim, Byeongchan Kim, Jinhu Kim, Na-Young Seo, Hyeonho Kim, Jaewon Ko

PLoS Biol· December 2025

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Development of New IL-1R Antagonists with Improved Anti-inflammatory Efficacy.
Mooseok Kang, Ae-Ree Lee, Hyeji Jung, Gyubin Jang, Byeongchan Kim, Jaewon Ko

Theranostics· December 2025

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Neuronal mitochondrial disaggregase CLPB ameliorates Huntington's disease pathology in mice.
Hyeonho Kim, Gaeun Hyun, Seunghye Kim, Changmo Yu, Young-Gi Hong, Jaewon Ko

Theranostics· December 2025

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CASKIN2 mediates PTPσ-orchestrated transsynaptic mechanisms at excitatory synapses.
Kyung Ah Han, Gyubin Jang, Hee-Yoon Lee, Byeongchan Kim, Tayo Kanato, Jaewon Ko

Proc Natl Acad Sci U S A· November 2025

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Autism-associated ARHGEF9 variants impair GABAergic synapses and ultrasonic communication by reducing gephyrin phosphorylation.
Hyeji Jung, Byeongchan Kim, Gyubin Jang, Hyojung Lee, Younghye Kim, Jaewon Ko

Mol Psychiatry· October 2025

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LRRTM2 Functions as a Neurexin Ligand in Promoting Excitatory Synapse Formation.
Jaewon Ko, Marc V Fuccillo, Robert C Malenka, Thomas C Südhof

Neuron· August 2025

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EphB2 receptor tyrosine kinase-mediated excitatory synaptic functions are negatively modulated by MDGA2.
Hyeonho Kim, Younghyeon Jeon, Seunghye Kim, Yuxuan Guo, Dongwook Kim, Jaewon Ko

Prog Neurobiol· July 2025

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Autism-associated MDGA1 missense mutations impair distinct facets of central nervous system development.
Seungjoon Kim, Hyeonho Kim, Javier Pelayo, Sara Alvarez, Gyubin Jang, Jaewon Ko

medRxiv· June 2025

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The NLRP3 inflammasome in microglia regulates repetitive behavior by modulating NMDA glutamate receptor functions.
Hyeji Jung, Byeongchan Kim, Gyubin Jang, Hyeonho Kim, Ae-Ree Lee, Jaewon Ko

Cell Rep· May 2025

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Multifarious astrocyte-neuron dialog in shaping neural circuit architecture.
Khai H Ngoc, Younghyeon Jeon, Jaewon Ko, Ji Won Um

Trends Cell Biol· January 2025

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Peer effects on organizational commitment: Evidence from military cadets.
Seungju Hyun, Xyle Ku, Joonyoung Hu, Byeonghyeon Kim, Hoyoun Ki, Jaewon Ko

Mil Psychol· November 2024

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A Systematic Structure-Function Characterization of a Human Mutation in Neurexin-3α Reveals an Extracellular Modulatory Sequence That Stabilizes Neuroligin-1 Binding to Enhance the Postsynaptic Properties of Excitatory Synapses.
Eric G Stokes, Hyeonho Kim, Jaewon Ko, Jason Aoto

J Neurosci· October 2024

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Calsyntenins Function as Synaptogenic Adhesion Molecules in Concert with Neurexins.
Ji Won Um, Gopal Pramanik, Ji Seung Ko, Min-Young Song, Dongmin Lee, Katsuhiko Tabuchi, Jaewon Ko

Cell Rep· August 2024

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Correction: Calsyntenin-3 interacts with both α- and β-neurexins in the regulation of excitatory synaptic innervation in specific schaffer collateral pathways.
Hyeonho Kim, Dongwook Kim, Jinhu Kim, Hee-Yoon Lee, Dongseok Park, Keiko Matsuda, Jaewon Ko

J Biol Chem· July 2024

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Author Correction: Specification of neural circuit architecture shaped by context-dependent patterned LAR-RPTP microexons.
Kyung Ah Han, Taek-Han Yoon, Jinhu Kim, Jusung Lee, Ju Yeon Lee, Jaewon Ko

Nat Commun· July 2024

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Correction: Differentially altered social dominance- and cooperative-like behaviors in Shank2- and Shank3-mutant mice.
Kyung Ah Han, Taek Han Yoon, Jungsu Shin, Ji Won Um, Jaewon Ko

Mol Autism· July 2024

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MDGAs perform activity-dependent synapse type-specific suppression via distinct extracellular mechanisms.
Seungjoon Kim, Gyubin Jang, Hyeonho Kim, Dongseok Lim, Kyung Ah Han, Jaewon Ko

Proc Natl Acad Sci U S A· June 2024

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Loss of IQSEC3 Disrupts GABAergic Synapse Maintenance and Decreases Somatostatin Expression in the Hippocampus.
Seungjoon Kim, Hyeonho Kim, Dongseok Park, Jinhu Kim, Joohyeon Hong, Jaewon Ko

Cell Rep· May 2024

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Author Correction: Specification of neural circuit architecture shaped by context-dependent patterned LAR-RPTP microexons.
Kyung Ah Han, Taek-Han Yoon, Jinhu Kim, Jusung Lee, Ju Yeon Lee, Jaewon Ko

Nat Commun· March 2024

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Thermodynamic modulation of gephyrin condensation by inhibitory synapse components.
Gyehyun Lee, Seungjoon Kim, Da-Eun Hwang, Yu-Gon Eom, Gyubin Jang, Jaewon Ko

Proc Natl Acad Sci U S A· March 2024

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Specification of neural circuit architecture shaped by context-dependent patterned LAR-RPTP microexons.
Kyung Ah Han, Taek-Han Yoon, Jinhu Kim, Jusung Lee, Ju Yeon Lee, Jaewon Ko

Nat Commun· February 2024

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Intracellular signaling mechanisms that shape postsynaptic GABAergic synapses.
Hyeji Jung, Seungjoon Kim, Jaewon Ko, Ji Won Um

Curr Opin Neurobiol· August 2023

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Molecular Decrowding by Tissue Expansion Allows Precise Determination of the Spatial Distribution of Synaptic Proteins at a Nanometer Scale by exTEM.
Kang-Hoon Kim, Jubeen Yoon, Christian P Macks, Han-Eol Park, Jihyun Youn, Jaewon Ko

ACS Nano· June 2023

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Orchestration of synaptic functions by WAVE regulatory complex-mediated actin reorganization.
Kyung Ah Han, Jaewon Ko

Exp Mol Med· June 2023

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