Publications by authors named "Jaime Iranzo"

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Timescale and genetic linkage explain the variable impact of defense systems on horizontal gene transfer.
Yang Liu, João Botelho, Jaime Iranzo

Genome Res· February 2025

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Synergistic epistasis among cancer drivers can rescue early tumors from the accumulation of deleterious passengers.
Carla Alejandre, Jorge Calle-Espinosa, Jaime Iranzo

PLoS Comput Biol· April 2024

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Dynamics of CRISPR-mediated virus-host interactions in the human gut microbiome.
Adrián López-Beltrán, João Botelho, Jaime Iranzo

ISME J· January 2024

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Comparison of gene clustering criteria reveals intrinsic uncertainty in pangenome analyses.
Saioa Manzano-Morales, Yang Liu, Sara González-Bodí, Jaime Huerta-Cepas, Jaime Iranzo

Genome Biol· October 2023

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Protocol for comparing gene-level selection on coding mutations between two groups of samples with Coselens.
Jaime Iranzo, George Gruenhagen, Jorge Calle-Espinosa, Eugene V Koonin

STAR Protoc· March 2023

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Pervasive conditional selection of driver mutations and modular epistasis networks in cancer.
Jaime Iranzo, George Gruenhagen, Jorge Calle-Espinosa, Eugene V Koonin

Cell Rep· August 2022

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UG/Abi: a highly diverse family of prokaryotic reverse transcriptases associated with defense functions.
Mario Rodríguez Mestre, Linyi Alex Gao, Shiraz A Shah, Adrián López-Beltrán, Alejandro González-Delgado, Jaime Iranzo

Nucleic Acids Res· June 2022

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Genomes of the " Actinomarinales" Order: Highly Streamlined Marine Epipelagic Actinobacteria.
Mario López-Pérez, Jose M Haro-Moreno, Jaime Iranzo, Francisco Rodriguez-Valera

mSystems· December 2020

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High density of unrepaired genomic ribonucleotides leads to Topoisomerase 1-mediated severe growth defects in absence of ribonucleotide reductase.
Susana M Cerritelli, Jaime Iranzo, Sushma Sharma, Andrei Chabes, Robert J Crouch

Nucleic Acids Res· May 2020

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Game-Theoretical Modeling of Interviral Conflicts Mediated by Mini-CRISPR Arrays.
Jaime Iranzo, Guilhem Faure, Yuri I Wolf, Eugene V Koonin

Front Microbiol· March 2020

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Evolutionary classification of CRISPR-Cas systems: a burst of class 2 and derived variants.
Kira S Makarova, Yuri I Wolf, Jaime Iranzo, Sergey A Shmakov, Omer S Alkhnbashi

Nat Rev Microbiol· February 2020

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Gene gain and loss push prokaryotes beyond the homologous recombination barrier and accelerate genome sequence divergence.
Jaime Iranzo, Yuri I Wolf, Eugene V Koonin, Itamar Sela

Nat Commun· November 2019

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Reply to Holmes and Duchêne, "Can Sequence Phylogenies Safely Infer the Origin of the Global Virome?": Deep Phylogenetic Analysis of RNA Viruses Is Highly Challenging but Not Meaningless.
Yuri I Wolf, Darius Kazlauskas, Jaime Iranzo, Adriana Lucía-Sanz, Jens H Kuhn

mBio· April 2019

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Origins and Evolution of the Global RNA Virome.
Yuri I Wolf, Darius Kazlauskas, Jaime Iranzo, Adriana Lucía-Sanz, Jens H Kuhn

mBio· November 2018

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Two RNase H2 Mutants with Differential rNMP Processing Activity Reveal a Threshold of Ribonucleotide Tolerance for Embryonic Development.
Ryo Uehara, Susana M Cerritelli, Naushaba Hasin, Kiran Sakhuja, Mariya London, Jaime Iranzo

Cell Rep· October 2018

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Cancer-mutation network and the number and specificity of driver mutations.
Jaime Iranzo, Iñigo Martincorena, Eugene V Koonin

Proc Natl Acad Sci U S A· June 2018

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Viruses of archaea: Structural, functional, environmental and evolutionary genomics.
Mart Krupovic, Virginija Cvirkaite-Krupovic, Jaime Iranzo, David Prangishvili, Eugene V Koonin

Virus Res· January 2018

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The enigmatic archaeal virosphere.
David Prangishvili, Dennis H Bamford, Patrick Forterre, Jaime Iranzo, Eugene V Koonin

Nat Rev Microbiol· November 2017

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Disentangling the effects of selection and loss bias on gene dynamics.
Jaime Iranzo, José A Cuesta, Susanna Manrubia, Mikhail I Katsnelson, Eugene V Koonin

Proc Natl Acad Sci U S A· July 2017

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Myosin-driven transport network in plants.
Elizabeth G Kurth, Valera V Peremyslov, Hannah L Turner, Kira S Makarova, Jaime Iranzo

Proc Natl Acad Sci U S A· February 2017

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A network perspective on the virus world.
Jaime Iranzo, Mart Krupovic, Eugene V Koonin

Commun Integr Biol· February 2017

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Bipartite Network Analysis of the Archaeal Virosphere: Evolutionary Connections between Viruses and Capsidless Mobile Elements.
Jaime Iranzo, Eugene V Koonin, David Prangishvili, Mart Krupovic

J Virol· December 2016

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Competition among networks highlights the power of the weak.
Jaime Iranzo, Javier M Buldú, Jacobo Aguirre

Nat Commun· November 2016

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Inevitability of Genetic Parasites.
Jaime Iranzo, Pere Puigbò, Alexander E Lobkovsky, Yuri I Wolf, Eugene V Koonin

Genome Biol Evol· September 2016

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The Double-Stranded DNA Virosphere as a Modular Hierarchical Network of Gene Sharing.
Jaime Iranzo, Mart Krupovic, Eugene V Koonin

mBio· August 2016

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