Publications by authors named "Jak Grimes"

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Plasma membrane preassociation drives β-arrestin coupling to receptors and activation.
Jak Grimes, Zsombor Koszegi, Yann Lanoiselée, Tamara Miljus, Shannon L O'Brien

Cell· May 2023

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How Carvedilol activates β-adrenoceptors.
Tobias Benkel, Mirjam Zimmermann, Julian Zeiner, Sergi Bravo, Nicole Merten, Jak Grimes

Nat Commun· November 2022

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Detecting Transient Trapping from a Single Trajectory: A Structural Approach.
Yann Lanoiselée, Jak Grimes, Zsombor Koszegi, Davide Calebiro

Entropy (Basel)· August 2021

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G Protein-Coupled Receptor Pharmacology at the Single-Molecule Level.
Davide Calebiro, Jak Grimes

Annu Rev Pharmacol Toxicol· January 2020

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MrgX2 is a promiscuous receptor for basic peptides causing mast cell pseudo-allergic and anaphylactoid reactions.
Jak Grimes, Sapna Desai, Neil W Charter, James Lodge, Rita Moita Santos

Pharmacol Res Perspect· December 2019

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Agonist-induced membrane nanodomain clustering drives GLP-1 receptor responses in pancreatic beta cells.
Teresa Buenaventura, Stavroula Bitsi, William E Laughlin, Thomas Burgoyne, Zekun Lyu, Jak Grimes

PLoS Biol· August 2019

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