Publications by authors named "Jake Gagnon"

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Inhibition of immune response reduces pathology in dorsal root ganglia and peripheral nerves in cynomolgus macaques following AAV gene therapy.
Branka Grubor, Kate L Henry, Su Jing Chan, Mark Sheehan, Anumeha Shah, Jake Gagnon

Mol Ther Methods Clin Dev· December 2025

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: a superfast and scalable single-cell RNA-seq data analysis pipeline powered by GPU.
Wenxing Hu, Haotian Zhang, Yu H Sun, Shaolong Cao, Jake Gagnon

Bioinform Adv· July 2025

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FundusNet: A Deep-Learning Approach for Fast Diagnosis of Neurodegenerative and Eye Diseases Using Fundus Images.
Wenxing Hu, Kejie Li, Jake Gagnon, Ye Wang, Talia Raney

Bioengineering (Basel)· January 2025

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Blood protein assessment of leading incident diseases and mortality in the UK Biobank.
Danni A Gadd, Robert F Hillary, Zhana Kuncheva, Tasos Mangelis, Yipeng Cheng, Jake Gagnon

Nat Aging· July 2024

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TDP-43-stratified single-cell proteomics of postmortem human spinal motor neurons reveals protein dynamics in amyotrophic lateral sclerosis.
Amanda J Guise, Santosh A Misal, Richard Carson, Jen-Hwa Chu, Hannah Boekweg, Jake Gagnon

Cell Rep· January 2024

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A novel method for quantitation of AAV genome integrity using duplex digital PCR.
Lauren Tereshko, Xiaohui Zhao, Jake Gagnon, Tinchi Lin, Trevor Ewald

PLoS One· December 2023

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TDP-43-stratified single-cell proteomic profiling of postmortem human spinal motor neurons reveals protein dynamics in amyotrophic lateral sclerosis.
Amanda J Guise, Santosh A Misal, Richard Carson, Hannah Boekweg, Daisha Van Der Watt, Jake Gagnon

bioRxiv· June 2023

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Independent study demonstrates amyloid probability score accurately indicates amyloid pathology.
Ilana Fogelman, Tim West, Joel B Braunstein, Philip B Verghese, Kristopher M Kirmess, Jake Gagnon

Ann Clin Transl Neurol· May 2023

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Recommendations of scRNA-seq Differential Gene Expression Analysis Based on Comprehensive Benchmarking.
Jake Gagnon, Lira Pi, Matthew Ryals, Qingwen Wan, Wenxing Hu

Life (Basel)· June 2022

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Cell-autonomous and non-cell autonomous effects of neuronal BIN1 loss in vivo.
Kathleen M McAvoy, Hameetha Rajamohamed Sait, Galina Marsh, Michael Peterson, Taylor L Reynolds, Jake Gagnon

PLoS One· March 2020

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