Publications by authors named "Jake Higgins"

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Application of error-corrected sequencing technologies for in vivo regulatory mutagenicity assessment.
Carole L Yauk, Anthony M Lynch, Vasily N Dobrovolsky, Maik Schuler, Stephanie L Smith-Roe, Jake Higgins

Regul Toxicol Pharmacol· January 2026

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Transferability, Reproducibility and Sensitivity of Mutation Quantification by Duplex Sequencing.
Shaofei Zhang, Barbara L Parsons, Devon Fitzgerald, Anne Ashford, James Todd Auman, Jake Higgins

Environ Mol Mutagen· August 2025

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Author Correction: Frequency and spectrum of mutations in human sperm measured using duplex sequencing correlate with trio-based de novo mutation analyses.
Jonatan Axelsson, Danielle LeBlanc, Habiballah Shojaeisaadi, Matthew J Meier, Devon M Fitzgerald, Jake Higgins

Sci Rep· December 2024

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Frequency and spectrum of mutations in human sperm measured using duplex sequencing correlate with trio-based de novo mutation analyses.
Jonatan Axelsson, Danielle LeBlanc, Habiballah Shojaeisaadi, Matthew J Meier, Devon M Fitzgerald, Jake Higgins

Sci Rep· October 2024

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Measurable Residual FLT3 Internal Tandem Duplication Before Allogeneic Transplant for Acute Myeloid Leukemia.
Laura W Dillon, Gege Gui, Niveditha Ravindra, Georgia Andrew, Devdeep Mukherjee, Jake Higgins

JAMA Oncol· August 2024

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Quantification of measurable residual disease using duplex sequencing in adults with acute myeloid leukemia.
Laura W Dillon, Jake Higgins, Hassan Nasif, Megan Othus, Lan Beppu

Haematologica· February 2024

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svCapture: efficient and specific detection of very low frequency structural variant junctions by error-minimized capture sequencing.
Thomas E Wilson, Samreen Ahmed, Jake Higgins, Jesse J Salk, Thomas W Glover

NAR Genom Bioinform· June 2023

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Quantification of measurable residual disease using duplex sequencing in adults with acute myeloid leukemia.
Laura W Dillon, Jake Higgins, Hassan Nasif, Megan Othus, Lan Beppu

medRxiv· March 2023

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Ultra-accurate Duplex Sequencing for the assessment of pretreatment ABL1 kinase domain mutations in Ph+ ALL.
Nicholas J Short, Hagop Kantarjian, Rashmi Kanagal-Shamanna, Koji Sasaki, Farhad Ravandi, Jake Higgins

Blood Cancer J· May 2020

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Considerations in repetitive activation of light sensitive ion channels for long-term studies: Channel rhodopsin in the Drosophila model.
Jake Higgins, Christina Hermanns, Cole Malloy, Robin L Cooper

Neurosci Res· December 2017

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Interaction of the Androgen Receptor, ETV1, and PTEN Pathways in Mouse Prostate Varies with Pathological Stage and Predicts Cancer Progression.
Jake Higgins, Michele Brogley, Nallasivam Palanisamy, Rohit Mehra, Michael M Ittmann

Horm Cancer· June 2015

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Disrupting SUMOylation enhances transcriptional function and ameliorates polyglutamine androgen receptor-mediated disease.
Jason P Chua, Satya L Reddy, Zhigang Yu, Elisa Giorgetti, Heather L Montie, Jake Higgins

J Clin Invest· February 2015

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Response to DNA damage of CHEK2 missense mutations in familial breast cancer.
Wendy Roeb, Jake Higgins, Mary-Claire King

Hum Mol Genet· June 2012

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Five novel loci for inherited hearing loss mapped by SNP-based homozygosity profiles in Palestinian families.
Hashem Shahin, Tom Walsh, Amal Abu Rayyan, Ming K Lee, Jake Higgins

Eur J Hum Genet· April 2010

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Functional restoration of BRCA2 protein by secondary BRCA2 mutations in BRCA2-mutated ovarian carcinoma.
Wataru Sakai, Elizabeth M Swisher, Céline Jacquemont, Kurapaty Venkatapoorna Chandramohan, Fergus J Couch, Jake Higgins

Cancer Res· August 2009

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Secondary mutations as a mechanism of cisplatin resistance in BRCA2-mutated cancers.
Wataru Sakai, Elizabeth M Swisher, Beth Y Karlan, Mukesh K Agarwal, Jake Higgins

Nature· February 2008

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Spectrum of mutations in BRCA1, BRCA2, CHEK2, and TP53 in families at high risk of breast cancer.
Tom Walsh, Silvia Casadei, Kathryn Hale Coats, Elizabeth Swisher, Sunday M Stray, Jake Higgins

JAMA· March 2006

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