Publications by authors named "Jake Pirkkanen"

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Comparison of Acute and Protracted Gamma Irradiation Effects During Perinatal Development in Beagle Dogs.
Shayenthiran Sreetharan, Stephanie Puukila, Christine Lalonde, Jake Pirkkanen, Gayle E Woloschak

Radiat Res· February 2025

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The Role of Natural Background Radiation in Maintaining Genomic Stability in the CGL1 Human Hybrid Model System.
Jake Pirkkanen, Taylor Laframboise, Jayden Peterson, Alyssa Labelle, Forest Mahoney

Radiat Res· October 2024

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Protracted Exposure to a Sub-background Radiation Environment Negatively Impacts the Anhydrobiotic Recovery of Desiccated Yeast Sentinels.
Michel R Lapointe, Taylor Laframboise, Jake Pirkkanen, T C Tai, Simon J Lees

Health Phys· June 2024

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Acute Impacts of Ionizing Radiation Exposure on the Gastrointestinal Tract and Gut Microbiome in Mice.
Alexandra Jameus, Jessica Dougherty, Ramya Narendrula, Daniela Levert, Manon Valiquette, Jake Pirkkanen

Int J Mol Sci· March 2024

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Overexpression of FRA1 () Leads to Global Transcriptional Perturbations, Reduced Cellular Adhesion and Altered Cell Cycle Progression.
Wuroud Al-Khayyat, Jake Pirkkanen, Jessica Dougherty, Taylor Laframboise, Noah Dickinson

Cells· September 2023

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Genomic Loss and Epigenetic Silencing of the FOSL1 Tumor Suppressor Gene in Radiation-induced Neoplastic Transformation of Human CGL1 Cells Alters the Tumorigenic Phenotype In Vitro and In Vivo.
Jake Pirkkanen, Sujeenthar Tharmalingam, Christopher Thome, Helen Chin Sinex, Laura V Benjamin

Radiat Res· July 2023

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The REPAIR Project, a Deep-Underground Radiobiology Experiment Investigating the Biological Effects of Natural Background Radiation: The First 6 Years.
Jake Pirkkanen, Christine Lalonde, Michel Lapointe, Taylor Laframboise, Marc S Mendonca

Radiat Res· March 2023

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Radiation-Induced Alterations in Proliferation, Migration, and Adhesion in Lens Epithelial Cells and Implications for Cataract Development.
Graysen Vigneux, Jake Pirkkanen, Taylor Laframboise, Hallie Prescott, Sujeenthar Tharmalingam

Bioengineering (Basel)· January 2022

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DOSIMETRIC CHARACTERISATION OF A SUB-NATURAL BACKGROUND RADIATION ENVIRONMENT FOR RADIOBIOLOGY INVESTIGATIONS.
Konnor J Kennedy, Alexandre LeBlanc, Jake Pirkkanen, Christopher Thome, T C Tai

Radiat Prot Dosimetry· September 2021

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A novel specialized tissue culture incubator designed and engineered for radiobiology experiments in a sub-natural background radiation research environment.
Jake Pirkkanen, Taylor Laframboise, Peter Liimatainen, Tom Sonley, Stephen Stankiewicz

J Environ Radioact· March 2021

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Transcriptomic profiling of gamma ray induced mutants from the CGL1 human hybrid cell system reveals novel insights into the mechanisms of radiation-induced carcinogenesis.
Jake Pirkkanen, Sujeenthar Tharmalingam, Igor H Morais, Daniel Lam-Sidun, Christopher Thome

Free Radic Biol Med· December 2019

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Physical and chemical characterization of McIntyre Powder: An aluminum dust inhaled by miners to combat silicosis.
Andrew Zarnke, Pat E Rasmussen, Marie-Odile David, Housam Eidi, Konnor Kennedy, Jake Pirkkanen

J Occup Environ Hyg· November 2019

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The REPAIR Project: Examining the Biological Impacts of Sub-Background Radiation Exposure within SNOLAB, a Deep Underground Laboratory.
Christopher Thome, Sujeenthar Tharmalingam, Jake Pirkkanen, Andrew Zarnke, Taylor Laframboise

Radiat Res· October 2017

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The CGL1 (HeLa × Normal Skin Fibroblast) Human Hybrid Cell Line: A History of Ionizing Radiation Induced Effects on Neoplastic Transformation and Novel Future Directions in SNOLAB.
Jake S Pirkkanen, Douglas R Boreham, Marc S Mendonca

Radiat Res· October 2017

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