Publications by authors named "Jamal Tazi"

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From HIV to Inflammation: How RNA Biology Redefined Drug Discovery.
Jamal Tazi

Drug Discov Today· December 2025

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The RasGAP-associated endoribonuclease G3BP mediates stress granule assembly.
Hélène Tourrière, Karim Chebli, Latifa Zekri, Brice Courselaud, Jean Marie Blanchard, Jamal Tazi

J Cell Biol· November 2023

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Retract and Replace: The RasGAP-associated endoribonuclease G3BP assembles stress granules.
Hélène Tourrière, Karim Chebli, Latifa Zekri, Brice Courselaud, Jean Marie Blanchard, Jamal Tazi

J Cell Biol· November 2023

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ABX464 (Obefazimod) Upregulates miR-124 to Reduce Proinflammatory Markers in Inflammatory Bowel Diseases.
Cécile Apolit, Noëlie Campos, Audrey Vautrin, Christina Begon-Pescia, Laure Lapasset, Jamal Tazi

Clin Transl Gastroenterol· April 2023

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Specific and selective induction of miR-124 in immune cells by the quinoline ABX464: a transformative therapy for inflammatory diseases.
Jamal Tazi, Christina Begon-Pescia, Noëlie Campos, Cécile Apolit, Aude Garcel

Drug Discov Today· April 2021

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Modulation of Yorkie activity by alternative splicing is required for developmental stability.
Diwas Srivastava, Marion de Toledo, Laurent Manchon, Jamal Tazi, François Juge

EMBO J· February 2021

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Cyclin A2 maintains colon homeostasis and is a prognostic factor in colorectal cancer.
Yuchen Guo, Monica Gabola, Rossano Lattanzio, Conception Paul, Valérie Pinet, Jamal Tazi

J Clin Invest· February 2021

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The core spliceosomal factor U2AF1 controls cell-fate determination via the modulation of transcriptional networks.
Abdelhamid Mahdi Laaref, Laurent Manchon, Yacine Bareche, Laure Lapasset, Jamal Tazi

RNA Biol· June 2020

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Lamin C Counteracts Glucose Intolerance in Aging, Obesity, and Diabetes Through β-Cell Adaptation.
Marion de Toledo, Isabel C Lopez-Mejia, Patricia Cavelier, Marine Pratlong, Célia Barrachina, Jamal Tazi

Diabetes· April 2020

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Reply to "Phosphorylation of G3BP1-S149 does not influence stress granule assembly".
Hélène Tourrière, Jamal Tazi

J Cell Biol· July 2019

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Both anti-inflammatory and antiviral properties of novel drug candidate ABX464 are mediated by modulation of RNA splicing.
Audrey Vautrin, Laurent Manchon, Aude Garcel, Noëlie Campos, Laure Lapasset, Jamal Tazi

Sci Rep· January 2019

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Safety, tolerability and impact on viral reservoirs of the addition to antiretroviral therapy of ABX464, an investigational antiviral drug, in individuals living with HIV-1: a Phase IIa randomised controlled study.
Sofie Rutsaert, Jean-Marc Steens, Paul Gineste, Basiel Cole, Sam Kint, Jamal Tazi

J Virus Erad· January 2019

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Reversing HIV latency via sphingosine-1-phosphate receptor 1 signaling.
Charline Duquenne, Sandrine Gimenez, Adeline Guigues, Benjamin Viala, Caroline Boulouis, Jamal Tazi

AIDS· November 2017

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RNA sequencing analysis of activated macrophages treated with the anti-HIV ABX464 in intestinal inflammation.
Laurent Manchon, Karim Chebli, Laura Papon, Conception Paul, Aude Garcel, Jamal Tazi

Sci Data· October 2017

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Safety, Pharmacokinetics, and Antiviral Activity of a Novel HIV Antiviral, ABX464, in Treatment-Naive HIV-Infected Subjects in a Phase 2 Randomized, Controlled Study.
Jean-Marc Steens, Didier Scherrer, Paul Gineste, P Noel Barrett, Supparatpino Khuanchai, Jamal Tazi

Antimicrob Agents Chemother· July 2017

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The Anti-Hiv Candidate Abx464 Dampens Intestinal Inflammation by Triggering Il-22 Production in Activated Macrophages.
Karim Chebli, Laura Papon, Conception Paul, Aude Garcel, Noëlie Campos, Jamal Tazi

Sci Rep· July 2017

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Pharmacokinetics and tolerability of ABX464, a novel first-in-class compound to treat HIV infection, in healthy HIV-uninfected subjects.
Didier Scherrer, Regine Rouzier, P Noel Barrett, Jean-Marc Steens, Paul Gineste, Jamal Tazi

J Antimicrob Chemother· March 2017

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Randomized Trial of Food Effect on Pharmacokinetic Parameters of ABX464 Administered Orally to Healthy Male Subjects.
Didier Scherrer, Regine Rouzier, Marine Cardona, P Noel Barrett, Jean-Marc Steens, Jamal Tazi

Antimicrob Agents Chemother· January 2017

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Preferential binding of a stable G3BP ribonucleoprotein complex to intron-retaining transcripts in mouse brain and modulation of their expression in the cerebellum.
Sophie Martin, Nicolas Bellora, Juan González-Vallinas, Manuel Irimia, Karim Chebli, Jamal Tazi

J Neurochem· November 2016

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A role for the serine/arginine-rich (SR) protein B52/SRSF6 in cell growth and myc expression in Drosophila.
Céline Fernando, Agnès Audibert, Françoise Simon, Jamal Tazi, François Juge

Genetics· April 2015

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Long lasting control of viral rebound with a new drug ABX464 targeting Rev - mediated viral RNA biogenesis.
Noëlie Campos, Renier Myburgh, Aude Garcel, Audrey Vautrin, Laure Lapasset, Jamal Tazi

Retrovirology· April 2015

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Antagonistic functions of LMNA isoforms in energy expenditure and lifespan.
Isabel C Lopez-Mejia, Marion de Toledo, Carine Chavey, Laure Lapasset, Patricia Cavelier, Jamal Tazi

EMBO Rep· May 2014

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Visualization of G3BP stress granules dynamics in live primary cells.
Sophie Martin, Jamal Tazi

J Vis Exp· May 2014

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MBNL1 and RBFOX2 cooperate to establish a splicing programme involved in pluripotent stem cell differentiation.
Julian P Venables, Laure Lapasset, Gilles Gadea, Philippe Fort, Roscoe Klinck, Jamal Tazi

Nat Commun· April 2014

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The sirtuin SIRT6 regulates stress granule formation in C. elegans and mammals.
Monika Jedrusik-Bode, Maja Studencka, Christian Smolka, Tobias Baumann, Henning Schmidt, Jamal Tazi

J Cell Sci· November 2013

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