Publications by authors named "James Adjaye"

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Human Urine-Derived SIX2-Positive Renal Progenitor Cells Partially Improve Kidney Fibrosis by Paracrine Signaling.
Claus Kordes, Lucas-Sebastian Spitzhorn, Martina Bohndorf, Audrey Ncube, Chantelle Thimm, James Adjaye

Stem Cells Dev· November 2025

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Modelling APOL1-mediated kidney inflammation and fibrosis using a partially reprogrammed urine-derived SIX2-positive renal progenitor cell line.
Chantelle Thimm, Rosanne Mack, Osmond Adjei-Aruna, Wasco Wruck, Dalvir Kular, James Adjaye

Stem Cell Res Ther· November 2025

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Generation of an induced pluripotent stem cell line HHUUKDi013-A (ISRM-AATD-iPSC-3) from a pediatric patient of Alpha-I Antitrypsin Deficiency (AATD).
Christiane Loerch, Rabea Hokamp, Wasco Wruck, David Katzer, Alexander Weigert, James Adjaye

Stem Cell Res· September 2025

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Generation of a Bartter syndrome type 3 patient-derived induced pluripotent stem cell line ISRM-BS3-UM18-iPSC (HHUUKDi014-A).
Chantelle Thimm, Chutong Zhong, Wasco Wruck, Alessandra Grillo, Rosanne Mack, James Adjaye

Stem Cell Res· September 2025

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Corrigendum to "Generation of a Bartter syndrome type 3 patient-derived induced pluripotent stem cell line ISRM-BS3_UM18-iPSC (HHUUKDi014-A)" [Stem Cell Res. 87 (2025) 103760].
Chantelle Thimm, Chutong Zhong, Wasco Wruck, Alessandra Grillo, Rosanne Mack, James Adjaye

Stem Cell Res· September 2025

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Impact of nephrotoxins and oxidants on survival and transport function of hiPSC-derived renal proximal tubular cells.
Isaac Musong Mboni-Johnston, Sören Hartmann, Christian Kroll, Carsten Berndt, James Adjaye

Arch Toxicol· June 2025

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Single Cell Data Enables Dissecting Cell Types Present in Bulk Transcriptome Data.
Wasco Wruck, James Adjaye

Stem Cells Dev· January 2025

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Publisher Correction: Hemozoin induces malaria via activation of DNA damage, p38 MAPK and neurodegenerative pathways in a human iPSC-derived neuronal model of cerebral malaria.
Abida Lslam Pranty, Leon-Phillip Szepanowski, Wasco Wruck, Akua Afriyie Karikari, James Adjaye

Sci Rep· November 2024

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Hemozoin induces malaria via activation of DNA damage, p38 MAPK and neurodegenerative pathways in a human iPSC-derived neuronal model of cerebral malaria.
Abida Islam Pranty, Leon-Phillip Szepanowski, Wasco Wruck, Akua Afriyie Karikari, James Adjaye

Sci Rep· October 2024

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Molecular and epigenetic ex vivo profiling of testis cancer-associated fibroblasts and their interaction with germ cell tumor cells and macrophages.
Alexa Stephan, Jan-Henrik Suhrmann, Margaretha A Skowron, Yue Che, Gereon Poschmann, James Adjaye

Matrix Biol· September 2024

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Gene expression profiling in porocarcinoma indicates heterogeneous tumor development and substantiates poromas as precursor lesions.
Svenja Holst, Anna K Weber, Friedegund Meier, Jörg Otte, Patrick Petzsch, James Adjaye

J Dtsch Dermatol Ges· August 2024

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Valproic Acid Confers Functional Pluripotency to Human Amniotic Fluid Stem Cells in a Transgene-free Approach.
Dafni Moschidou, Sayandip Mukherjee, Michael P Blundell, Katharina Drews, Gemma N Jones, James Adjaye

Mol Ther· August 2024

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Untangling the Uncertain Role of Overactivation of the Renin-Angiotensin-Aldosterone System with the Aging Process Based on Sodium Wasting Human Models.
Chantelle Thimm, James Adjaye

Int J Mol Sci· August 2024

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Forskolin induces FXR expression and enhances maturation of iPSC-derived hepatocyte-like cells.
Christiane Loerch, Leon-Phillip Szepanowski, Julian Reiss, James Adjaye, Nina Graffmann

Front Cell Dev Biol· April 2024

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Cockayne Syndrome Patient iPSC-Derived Brain Organoids and Neurospheres Show Early Transcriptional Dysregulation of Biological Processes Associated with Brain Development and Metabolism.
Leon-Phillip Szepanowski, Wasco Wruck, Julia Kapr, Andrea Rossi, Ellen Fritsche, James Adjaye

Cells· March 2024

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Sensitivity of Human Induced Pluripotent Stem Cells and Thereof Differentiated Kidney Proximal Tubular Cells towards Selected Nephrotoxins.
Isaac Musong Mboni-Johnston, Nazih Mohamed Zakari Kouidrat, Cornelia Hirsch, Andreas Georg Weber, Alexander Meißner, James Adjaye

Int J Mol Sci· December 2023

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Generation of two Alpha-I antitrypsin deficiency patient-derived induced pluripotent stem cell lines ISRM-AATD-iPSC-1 (HHUUKDi011-A) and ISRM-AATD-iPSC-2 (HHUUKDi012-A).
Audrey Ncube, Lisa Bewersdorf, Lucas-Sebastian Spitzhorn, Christiane Loerch, Martina Bohndorf, James Adjaye

Stem Cell Res· September 2023

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JNK Signalling Regulates Self-Renewal of Proliferative Urine-Derived Renal Progenitor Cells via Inhibition of Ferroptosis.
Lisa Nguyen, Leonie Thewes, Michelle Westerhoff, Wasco Wruck, Andreas S Reichert, James Adjaye

Cells· September 2023

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Free Bilirubin Induces Neuro-Inflammation in an Induced Pluripotent Stem Cell-Derived Cortical Organoid Model of Crigler-Najjar Syndrome.
Abida Islam Pranty, Wasco Wruck, James Adjaye

Cells· September 2023

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Natural Products in Renal-Associated Drug Discovery.
Wasco Wruck, Afua Kobi Ampem Genfi, James Adjaye

Antioxidants (Basel)· August 2023

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Unveiling Angiotensin II and Losartan-Induced Gene Regulatory Networks Using Human Urine-Derived Podocytes.
Chantelle Thimm, Lars Erichsen, Wasco Wruck, James Adjaye

Int J Mol Sci· June 2023

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Secreted Cytokines within the Urine of AKI Patients Modulate TP53 and SIRT1 Levels in a Human Podocyte Cell Model.
Lars Erichsen, Chantelle Thimm, Wasco Wruck, Daniela Kaierle, Manon Schless, James Adjaye

Int J Mol Sci· May 2023

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Gene expression studies of WT1 mutant Wilms tumor cell lines in the frame work of published kidney development data reveals their early kidney stem cell origin.
Brigitte Royer-Pokora, Wasco Wruck, James Adjaye, Manfred Beier

PLoS One· January 2023

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Derivation of the Immortalized Cell Line UM51-PrePodo-hTERT and Its Responsiveness to Angiotensin II and Activation of the RAAS Pathway.
Lars Erichsen, Lea Doris Friedel Kloss, Chantelle Thimm, Martina Bohndorf, Kira Schichel, James Adjaye

Cells· January 2023

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Urine-Based Detection of Biomarkers Indicative of Chronic Kidney Disease in a Patient Cohort from Ghana.
Wasco Wruck, Vincent Boima, Lars Erichsen, Chantelle Thimm, Theresa Koranteng, James Adjaye

J Pers Med· December 2022

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