Publications by authors named "James Barrow"

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IP6 Kinase Inhibitor Screening Assays.
Huijun Wei, James C Barrow

Methods Mol Biol· August 2025

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Ribosomal RNA transcription regulates splicing through ribosomal protein RPL22.
Wenjun Fan, Hester Liu, Gregory C Stachelek, Asma Begum, Catherine E Davis, James C Barrow

Cell Chem Biol· July 2025

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Development and characterization of pyridyl carboxamides as potent and highly selective Na1.8 inhibitors.
Michael Poslusney, Glen Ernst, Yifang Huang, Aaron C Gerlach, Mark L Chapman, James C Barrow

Bioorg Med Chem Lett· March 2025

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Identification and Characterization of a Blood-Brain Barrier Penetrant Inositol Hexakisphosphate Kinase (IP6K) Inhibitor.
Tyler Heitmann, Gangling Liao, Glen Ernst, Michael Poslusney, Thomas van Kralingen, James C Barrow

J Med Chem· August 2024

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Ribosomal RNA transcription governs splicing through ribosomal protein RPL22.
Wenjun Fan, Hester Liu, Gregory C Stachelek, Asma Begum, Catherine E Davis, James C Barrow

bioRxiv· August 2024

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Fragment-Based Screening Identifies New Quinazolinone-Based Inositol Hexakisphosphate Kinase (IP6K) Inhibitors.
Tyler Heitmann, Gangling Liao, Pablo de León, Glen Ernst, Ingrid Buchler, James C Barrow

ACS Med Chem Lett· December 2023

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Degrading stimuli by reducing image resolution impairs performance in a rodent continuous performance test.
Adrienne C DeBrosse, Ye Li, Robyn Wiseman, Racine Ross, Sy'Keria Garrison, James C Barrow

Behav Processes· October 2023

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The Role of Inositol Hexakisphosphate Kinase in the Central Nervous System.
Tyler Heitmann, James C Barrow

Biomolecules· August 2023

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The IP6K Inhibitor LI-2242 Ameliorates Diet-Induced Obesity, Hyperglycemia, and Hepatic Steatosis in Mice by Improving Cell Metabolism and Insulin Signaling.
Sandip Mukherjee, Molee Chakraborty, Jake Haubner, Glen Ernst, Michael DePasquale, James C Barrow

Biomolecules· May 2023

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The Importance of PK-PD.
James C Barrow, Craig W Lindsley

J Med Chem· April 2023

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Discovery and Evaluation of Novel Angular Fused Pyridoquinazolinonecarboxamides as RNA Polymerase I Inhibitors.
Tony E Dorado, Pablo de León, Asma Begum, Hester Liu, Daming Chen, James C Barrow

ACS Med Chem Lett· April 2022

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Simplifying Submission Requirements for the .
Craig W Lindsley, James Barrow, Kelly Chibale, Maria Laura Bolognesi, Stuart Conway

J Med Chem· June 2021

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Membrane bound catechol-O-methytransferase is the dominant isoform for dopamine metabolism in PC12 cells and rat brain.
Yupin Su, Michael DePasquale, Gangling Liao, Ingrid Buchler, Gongliang Zhang, James Barrow

Eur J Pharmacol· April 2021

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Identification of Small-Molecule Inhibitors of Human Inositol Hexakisphosphate Kinases by High-Throughput Screening.
Gangling Liao, Wenjuan Ye, Tyler Heitmann, Glen Ernst, Michael DePasquale, James Barrow

ACS Pharmacol Transl Sci· April 2021

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The angiogenic potential of CD271+ human adipose tissue-derived mesenchymal stem cells.
Richard J P Smith, Alessandro Faroni, James R Barrow, Jamie Soul, Adam J Reid

Stem Cell Res Ther· March 2021

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Post-weaning social isolation increases ΔFosB/FosB protein expression in sex-specific patterns in the prelimbic/infralimbic cortex and hippocampus in mice.
Michael Noback, Gongliang Zhang, Noelle White, James C Barrow, Gregory V Carr

Neurosci Lett· January 2021

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Novel, non-nitrocatechol catechol-O-methyltransferase inhibitors modulate dopamine neurotransmission in the frontal cortex and improve cognitive flexibility.
Spencer Byers, Ingrid P Buchler, Michael DePasquale, Helen L Rowley, Rajiv S Kulkarni, James C Barrow

Psychopharmacology (Berl)· September 2020

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Inositol Pyrophosphates Mediate the DNA-PK/ATM-p53 Cell Death Pathway by Regulating CK2 Phosphorylation of Tti1/Tel2.
Feng Rao, Jiyoung Cha, Jing Xu, Risheng Xu, M Scott Vandiver, Roxanne Barrow, James C Barrow

Mol Cell· August 2020

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Inhibition of Catechol--methyltransferase Does Not Alter Effort-Related Choice Behavior in a Fixed Ratio/Concurrent Chow Task in Male Mice.
Adrienne C DeBrosse, Abigail M Wheeler, James C Barrow, Gregory V Carr

Front Behav Neurosci· May 2020

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Dissecting transcriptomic signatures of neuronal differentiation and maturation using iPSCs.
Emily E Burke, Joshua G Chenoweth, Joo Heon Shin, Leonardo Collado-Torres, Suel-Kee Kim, James C Barrow

Nat Commun· January 2020

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Synthesis and Evaluation of Bicyclic Hydroxypyridones as Inhibitors of Catechol -Methyltransferase.
Glen Ernst, Daniel Akuma, Vinh Au, Ingrid P Buchler, Spencer Byers, James C Barrow

ACS Med Chem Lett· November 2019

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Synthesis and characterization of novel isoform-selective IP6K1 inhibitors.
Michael M Wormald, Glen Ernst, Huijun Wei, James C Barrow

Bioorg Med Chem Lett· October 2019

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Development of a PC12 Cell Based Assay for Screening Catechol--methyltransferase Inhibitors.
Gongliang Zhang, Ingrid P Buchler, Michael DePasquale, Michael Wormald, Gangling Liao, James C Barrow

ACS Chem Neurosci· October 2019

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The influence of short-term fixture congestion on position specific match running performance and external loading patterns in English professional soccer.
Ross Nicholas Jones, Matt Greig, Youl Mawéné, James Barrow, Richard Michael Page

J Sports Sci· June 2019

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A Medicinal Chemist's Perspective on Transitioning from Industry to Academic Drug Discovery.
James C Barrow

ACS Med Chem Lett· May 2019

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