Publications by authors named "James Cardia"

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Self-delivering RNAi immunotherapeutic PH-762 silences PD-1 to generate local and abscopal antitumor efficacy.
Benjamin Cuiffo, Melissa Maxwell, Dingxue Yan, Ramdane Guemiri, Andrew Boone, James Cardia

Front Immunol· December 2024

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Self-Delivering RNAi Compounds for Reduction of Hyperpigmentation.
Melissa Maxwell, Katherine Holton, Richard J Looby, Michael Byrne, James Cardia

Clin Cosmet Investig Dermatol· December 2024

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INTASYL self-delivering RNAi decreases TIGIT expression, enhancing NK cell cytotoxicity: a potential application to increase the efficacy of NK adoptive cell therapy against cancer.
Melissa Maxwell, Dingxue Yan, Brianna Rivest, Andrew Boone, James Cardia

Cancer Immunol Immunother· October 2024

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Self-delivering RNAi compounds as therapeutic agents in the central nervous system to enhance axonal regeneration after injury.
Sarah A Woller, Joerg Ruschel, Barbara Morquette, James Cardia, Dinxue Yan

iScience· June 2022

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Visualization of self-delivering hydrophobically modified siRNA cellular internalization.
Socheata Ly, Deanna M Navaroli, Marie-Cécile Didiot, James Cardia, Lakshmipathi Pandarinathan

Nucleic Acids Res· January 2017

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Diphencyprone Treatment of Alopecia Areata: Postulated Mechanism of Action and Prospects for Therapeutic Synergy with RNA Interference.
Karen G Bulock, James P Cardia, Pamela A Pavco, William R Levis

J Investig Dermatol Symp Proc· November 2015

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Novel hydrophobically modified asymmetric RNAi compounds (sd-rxRNA) demonstrate robust efficacy in the eye.
Michael Byrne, Radouil Tzekov, Yi Wang, Amanda Rodgers, James Cardia

J Ocul Pharmacol Ther· December 2013

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Rabenosyn-5 defines the fate of the transferrin receptor following clathrin-mediated endocytosis.
Deanna M Navaroli, Karl D Bellvé, Clive Standley, Lawrence M Lifshitz, James Cardia

Proc Natl Acad Sci U S A· February 2012

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Potent and systematic RNAi mediated silencing with single oligonucleotide compounds.
Jennifer Lapierre, William Salomon, James Cardia, Karen Bulock, Jessica T Lam

RNA· June 2011

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Monoalkylglycerol ether lipids promote adipogenesis.
Edwin A Homan, Yun-Gon Kim, James P Cardia, Alan Saghatelian

J Am Chem Soc· April 2011

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Use of L-asparagine and N-phosphonacetyl-L-asparagine to investigate the linkage of catalysis and homotropic cooperativity in E. coli aspartate transcarbomoylase.
James P Cardia, Joby Eldo, Jiarong Xia, Elizabeth M O'Day, Hiro Tsuruta

Proteins· May 2008

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N-phosphonacetyl-L-isoasparagine a potent and specific inhibitor of Escherichia coli aspartate transcarbamoylase.
Joby Eldo, James P Cardia, Elizabeth M O'Day, Jiarong Xia, Hiro Tsuruta

J Med Chem· October 2006

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T-state inhibitors of E. coli aspartate transcarbamoylase that prevent the allosteric transition.
Sabrina Heng, Kimberly A Stieglitz, Joby Eldo, Jiarong Xia, James P Cardia

Biochemistry· August 2006

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Structure of the E.coli aspartate transcarbamoylase trapped in the middle of the catalytic cycle.
Kimberly A Stieglitz, Kelly J Dusinberre, James P Cardia, Hiro Tsuruta, Evan R Kantrowitz

J Mol Biol· September 2005

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Structural basis for ordered substrate binding and cooperativity in aspartate transcarbamoylase.
Jie Wang, Kimberly A Stieglitz, James P Cardia, Evan R Kantrowitz

Proc Natl Acad Sci U S A· June 2005

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Alkaline phosphatase from the hyperthermophilic bacterium T. maritima requires cobalt for activity.
Cheryl L Wojciechowski, James P Cardia, Evan R Kantrowitz

Protein Sci· April 2002

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