Publications by authors named "James Dowell"

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A cellular model of TDP-43 induces phosphorylated TDP-43 aggregation with distinct changes in solubility and autophagy dysregulation.
Matthew B Dopler, Muhammad I Abeer, Sanaz Arezoumandan, Keyshawn Cox, Tyler L Petersen, James A Dowell

FEBS J· September 2025

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Safety and Pharmacokinetics of Taniborbactam (VNRX-5133) with Cefepime in Subjects with Various Degrees of Renal Impairment.
James A Dowell, Thomas C Marbury, William B Smith, Tim Henkel

Antimicrob Agents Chemother· September 2022

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Histone Acid Extraction and High Throughput Mass Spectrometry to Profile Histone Modifications in Arabidopsis thaliana.
Ray Scheid, James A Dowell, Dean Sanders, Jianjun Jiang, John M Denu

Curr Protoc· August 2022

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Metabolomic Analysis of Carbohydrate and Amino Acid Changes Induced by Hypoxia in Naked Mole-Rat Brain and Liver.
Hang Cheng, Yiming Amy Qin, Rashpal Dhillon, James Dowell, John M Denu

Metabolites· January 2022

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Safety and Pharmacokinetics in Human Volunteers of Taniborbactam (VNRX-5133), a Novel Intravenous β-Lactamase Inhibitor.
James A Dowell, Daniel Dickerson, Tim Henkel

Antimicrob Agents Chemother· October 2021

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Pharmacokinetics and safety of lefamulin after single intravenous dose administration in subjects with impaired renal function and those requiring hemodialysis.
Wolfgang W Wicha, Thomas C Marbury, James A Dowell, Jared L Crandon, Cathie Leister

Pharmacotherapy· May 2021

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Pharmacokinetics and safety of lefamulin after single intravenous dose administration in subjects with impaired-hepatic function.
Wolfgang W Wicha, Thomas C Marbury, James A Dowell, Jared L Crandon, Cathie Leister

Pharmacotherapy· May 2021

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Benchmarking Quantitative Performance in Label-Free Proteomics.
James A Dowell, Logan J Wright, Eric A Armstrong, John M Denu

ACS Omega· February 2021

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Site-Specific Lysine Acetylation Stoichiometry Across Subcellular Compartments.
Anastasia J Lindahl, Alexis J Lawton, Josue Baeza, James A Dowell, John M Denu

Methods Mol Biol· January 2020

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TDP-43 interacts with mitochondrial proteins critical for mitophagy and mitochondrial dynamics.
Stephani A Davis, Sheed Itaman, Christopher M Khalid-Janney, Justin A Sherard, James A Dowell

Neurosci Lett· June 2018

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Quantitative Mass Spectrometry Reveals Food Intake-Induced Neuropeptide Level Changes in Rat Brain: Functional Assessment of Selected Neuropeptides as Feeding Regulators.
Hui Ye, Jingxin Wang, Zichuan Tian, Fengfei Ma, James Dowell

Mol Cell Proteomics· November 2017

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TDP-43 expression influences amyloidβ plaque deposition and tau aggregation.
Stephani A Davis, Kok Ann Gan, James A Dowell, Nigel J Cairns, Michael A Gitcho

Neurobiol Dis· July 2017

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Histone Lysine-to-Methionine Mutations Reduce Histone Methylation and Cause Developmental Pleiotropy.
Dean Sanders, Shuiming Qian, Rachael Fieweger, Li Lu, James A Dowell

Plant Physiol· April 2017

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Iron Deprivation Induces Transcriptional Regulation of Mitochondrial Biogenesis.
Jarred W Rensvold, Kimberly A Krautkramer, James A Dowell, John M Denu, David J Pagliarini

J Biol Chem· September 2016

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Increased expression of AT-1/SLC33A1 causes an autistic-like phenotype in mice by affecting dendritic branching and spine formation.
Rikki Hullinger, Mi Li, Jingxin Wang, Yajing Peng, James A Dowell

J Exp Med· June 2016

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Quantification of SAHA-Dependent Changes in Histone Modifications Using Data-Independent Acquisition Mass Spectrometry.
Kimberly A Krautkramer, Lukas Reiter, John M Denu, James A Dowell

J Proteome Res· August 2015

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Mechanisms of Nrf2 protection in astrocytes as identified by quantitative proteomics and siRNA screening.
James A Dowell, Jeffrey A Johnson

PLoS One· August 2014

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Stoichiometry of site-specific lysine acetylation in an entire proteome.
Josue Baeza, James A Dowell, Michael J Smallegan, Jing Fan, Daniel Amador-Noguez

J Biol Chem· August 2014

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c-Jun N-terminal kinase regulates mGluR-dependent expression of post-synaptic FMRP target proteins.
Travis L Schmit, James A Dowell, Margaret E Maes, Michael Wilhelm

J Neurochem· December 2013

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Rat brain neuropeptidomics: tissue collection, protease inhibition, neuropeptide extraction, and mass spectrometric analysis.
Robert M Sturm, James A Dowell, Lingjun Li

Methods Mol Biol· February 2010

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Identification of astrocyte secreted proteins with a combination of shotgun proteomics and bioinformatics.
James A Dowell, Jeffrey A Johnson, Lingjun Li

J Proteome Res· August 2009

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Pharmacokinetics of dalbavancin in patients with renal or hepatic impairment.
Thomas Marbury, James A Dowell, Elyse Seltzer, Mary Buckwalter

J Clin Pharmacol· April 2009

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The Nrf2/ARE pathway as a potential therapeutic target in neurodegenerative disease.
Marcus J Calkins, Delinda A Johnson, Jessica A Townsend, Marcelo R Vargas, James A Dowell

Antioxid Redox Signal· March 2009

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In vitro and in vivo studies to characterize the clearance mechanism and potential cytochrome P450 interactions of anidulafungin.
Bharat D Damle, James A Dowell, Robert L Walsky, Gregory L Weber, Martin Stogniew

Antimicrob Agents Chemother· March 2009

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Mass spectrometric characterization of neuropeptides.
Stephanie S Cape, James A Dowell, Lingjun Li

Methods Mol Biol· March 2009

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