Publications by authors named "James Durkin"

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Discovery of potent iminoheterocycle BACE1 inhibitors.
John P Caldwell, Robert D Mazzola, James Durkin, Joseph Chen, Xia Chen

Bioorg Med Chem Lett· December 2014

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Structure based design of iminohydantoin BACE1 inhibitors: identification of an orally available, centrally active BACE1 inhibitor.
Jared N Cumming, Elizabeth M Smith, Lingyan Wang, Jeffrey Misiaszek, James Durkin

Bioorg Med Chem Lett· April 2012

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Cyclic hydroxyamidines as amide isosteres: discovery of oxadiazolines and oxadiazines as potent and highly efficacious γ-secretase modulators in vivo.
Zhong-Yue Sun, Theodros Asberom, Thomas Bara, Chad Bennett, Duane Burnett, James Durkin

J Med Chem· January 2012

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The use of two neuroleptics to treat bipolar illness in two children.
James P Durkin

J Child Adolesc Psychopharmacol· May 2005

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Aripiprazole in the treatment of bipolar disorder in children and adolescents.
James P Durkin

J Child Adolesc Psychopharmacol· May 2005

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Fluorescence polarization assay and inhibitor design for MDM2/p53 interaction.
Rumin Zhang, Todd Mayhood, Philip Lipari, Yaolin Wang, James Durkin

Anal Biochem· August 2004

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Application of the lambda-dynamics method to evaluate the relative binding free energies of inhibitors to HCV protease.
Zhuyan Guo, James Durkin, Thierry Fischmann, Richard Ingram, Andrew Prongay

J Med Chem· December 2003

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Gabapentin in complicated school refusal.
James P Durkin

J Am Acad Child Adolesc Psychiatry· June 2002

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Azapeptides as inhibitors of the hepatitis C virus NS3 serine protease.
Rumin Zhang, James P Durkin, William T Windsor

Bioorg Med Chem Lett· April 2002

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