Publications by authors named "James Fuchs"

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Erratum for Dinh et al., "The structural and mechanistic bases for the viral resistance to allosteric HIV-1 integrase inhibitor pirmitegravir".
Tung Dinh, Zahira Tber, Juan S Rey, Seema Mengshetti, Arun S Annamalai, James R Fuchs

mBio· December 2025

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Pentalinonsterol alters immune transcriptomic profiles and modulates the Nrf-2 pathway in Leishmania major infected macrophages.
M Junaid Dar, Sreenivas Gannavaram, Ryan H Huston, Charles Thomas, Hira L Nakhasi, James R Fuchs

Phytomedicine· November 2025

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Delineating Structural Functionalities of Lenacapavir Amenable to Modifications for Targeting Emerging Drug-Resistant HIV‑1 Capsid Variants.
Daniel Adu-Ampratwum, Arun S Annamalai, Tung Dinh, Jeffrey R Lockwood, Ross H Bockbrader, James R Fuchs

ACS Med Chem Lett· October 2025

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Antitumor and immunomodulatory activities of diphyllin and its derivatives.
Yulin Ren, Judith C Gallucci, Jianhua Yu, Joanna E Burdette, James R Fuchs

Bioorg Med Chem· July 2025

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Additional Bioactive Silvestrol Analogs from the Roots of Collected in Vietnam.
Ermias Mekuria Addo, Daniel Adu-Ampratwum, Elizabeth N Kaweesa, Garima Agarwal, Dmitriy Uchenik, James R Fuchs

J Nat Prod· March 2025

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The structural and mechanistic bases for the viral resistance to allosteric HIV-1 integrase inhibitor pirmitegravir.
Tung Dinh, Zahira Tber, Juan S Rey, Seema Mengshetti, Arun S Annamalai, James R Fuchs

mBio· November 2024

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Verticillins: fungal epipolythiodioxopiperazine alkaloids with chemotherapeutic potential.
Herma C Pierre, Chiraz Soumia M Amrine, Michael G Doyle, Amrita Salvi, Huzefa A Raja, James R Fuchs

Nat Prod Rep· September 2024

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Semisynthetic derivatives of the fungal metabolite eupenifeldin via targeting the tropolone hydroxy groups.
Zeinab Y Al Subeh, Herma C Pierre, Ross H Bockbrader, Robert J Tokarski, Amanda C Maldonado, James R Fuchs

Bioorg Med Chem Lett· September 2024

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Anti-tumor effects of the eIF4A inhibitor didesmethylrocaglamide and its derivatives in human and canine osteosarcomas.
Janet L Oblinger, Jack Wang, Georgia D Wetherell, Garima Agarwal, Tyler A Wilson, James R Fuchs

Sci Rep· August 2024

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Anti-tumor Effects of the eIF4A Inhibitor Didesmethylrocaglamide and Its Derivatives in Human and Canine Osteosarcomas.
Janet Oblinger, Jack Wang, Georgia Wetherell, Garima Agarwal, Tyler Wilson, James Fuchs

Res Sq· June 2024

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Identification of novel small molecule inhibitors of twin arginine translocation (Tat) pathway and their effect on the control of in chickens.
Loïc Deblais, Mary Drozd, Anand Kumar, Janet Antwi, James Fuchs

Front Microbiol· April 2024

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The structural and mechanistic bases for the viral resistance to allosteric HIV-1 integrase inhibitor pirmitegravir.
Tung Dinh, Zahira Tber, Juan S Rey, Seema Mengshetti, Arun S Annamalai, James R Fuchs

bioRxiv· January 2024

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Tomatidine targets ATF4-dependent signaling and induces ferroptosis to limit pancreatic cancer progression.
Debasmita Mukherjee, Srija Chakraborty, Lena Bercz, Liliana D'Alesio, Jessica Wedig, James R Fuchs

iScience· August 2023

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Discovery and development of botanical natural products and their analogues as therapeutics for ovarian cancer.
Brittney K Mize, Amrita Salvi, Yulin Ren, Joanna E Burdette, James R Fuchs

Nat Prod Rep· July 2023

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Examination of the Impact of Triazole Position within Linkers on Solubility and Lipophilicity of a CDK9 Degrader Series.
Oluwatosin R Ayinde, Chia Sharpe, Emily Stahl, Robert J Tokarski, James R Lerma, James R Fuchs

ACS Med Chem Lett· July 2023

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Bifunctional degraders of cyclin dependent kinase 9 (CDK9): Probing the relationship between linker length, properties, and selective protein degradation.
Robert J Tokarski, Chia M Sharpe, Andrew C Huntsman, Brittney K Mize, Oluwatosin R Ayinde, James R Fuchs

Eur J Med Chem· June 2023

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Exploration of Verticillins in High-Grade Serous Ovarian Cancer and Evaluation of Multiple Formulations in Preclinical In Vitro and In Vivo Models.
Elizabeth N Kaweesa, Jaqueline M Bazioli, Herma C Pierre, Daniel D Lantvit, Samuel K Kulp, James R Fuchs

Mol Pharm· June 2023

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GRetro as a two-step graph generative models for retrosynthesis prediction.
Ziqi Chen, Oluwatosin R Ayinde, James R Fuchs, Huan Sun, Xia Ning

Commun Chem· May 2023

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Efficacy of quorum sensing and growth inhibitors alone and in combination against avian pathogenic Escherichia coli infection in chickens.
Yosra A Helmy, Dipak Kathayat, Gary Closs, Katie Galgozy, James R Fuchs

Poult Sci· April 2023

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Structural and Mechanistic Bases of Viral Resistance to HIV-1 Capsid Inhibitor Lenacapavir.
Stephanie M Bester, Daniel Adu-Ampratwum, Arun S Annamalai, Guochao Wei, Lorenzo Briganti, James R Fuchs

mBio· October 2022

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Evaluation of Novel Quorum Sensing Inhibitors Targeting Auto-Inducer 2 (AI-2) for the Control of Avian Pathogenic Escherichia coli Infections in Chickens.
Yosra A Helmy, Dipak Kathayat, Loic Deblais, Vishal Srivastava, Gary Closs, James R Fuchs

Microbiol Spectr· June 2022

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Pentalinonsterol, a Phytosterol from Pentalinon andrieuxii, is Immunomodulatory through Phospholipase A in Macrophages toward its Antileishmanial Action.
Sanjay Varikuti, Andrew B Shelton, Sainath R Kotha, Travis Gurney, Gaurav Gupta, James R Fuchs

Cell Biochem Biophys· March 2022

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Discovery of Anticancer Agents of Diverse Natural Origin.
Leslie N Aldrich, Joanna E Burdette, Esperanza Carcache de Blanco, Christopher C Coss, Alessandra S Eustaquio, James R Fuchs

J Nat Prod· March 2022

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Identification and Optimization of a Novel HIV-1 Integrase Inhibitor.
Daniel Adu-Ampratwum, Yuhan Pan, Pratibha C Koneru, Janet Antwi, Ashley C Hoyte, James R Fuchs

ACS Omega· February 2022

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PHY34 inhibits autophagy through V-ATPase V0A2 subunit inhibition and CAS/CSE1L nuclear cargo trafficking in high grade serous ovarian cancer.
Amrita Salvi, Alexandria N Young, Andrew C Huntsman, Melissa R Pergande, Melissa A Korkmaz, James R Fuchs

Cell Death Dis· January 2022

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