Publications by authors named "James Goldman"

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The spatial landscape of glial pathology and T cell response in Parkinson's disease substantia nigra.
Maxwell Ma, Fahad Paryani, Kelly Jakubiak, Shengnan Xia, Susumu Antoku, James E Goldman

Nat Commun· August 2025

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The role of astrocytes in human Huntington's disease pathology.
Osama Al-Dalahmah, James E Goldman

J Huntingtons Dis· August 2025

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Impaired macroautophagy confers substantial risk for intellectual disability in children with autism spectrum disorders.
Ahrom Ham, Audrey Yuen Chang, Hongyu Li, Jennifer M Bain, James E Goldman

Mol Psychiatry· February 2025

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Cytoplasmic vacuolization and ectopic formation of perineuronal nets are characteristic pathologies of cytomegalic neurons in tuberous sclerosis.
Alexander A Sosunov, Guy McKhann Ii, Guomei Tang, James E Goldman

J Neuropathol Exp Neurol· December 2024

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Multi-omic analysis of Huntington's disease reveals a compensatory astrocyte state.
Fahad Paryani, Ji-Sun Kwon, Christopher W Ng, Kelly Jakubiak, Nacoya Madden, James E Goldman

Nat Commun· August 2024

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Osteopontin drives neuroinflammation and cell loss in MAPT-N279K frontotemporal dementia patient neurons.
Osama Al-Dalahmah, Matti Lam, Julie J McInvale, Wenhui Qu, Trang Nguyen, James E Goldman

Cell Stem Cell· May 2024

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The Matrix Receptor CD44 Is Present in Astrocytes throughout the Human Central Nervous System and Accumulates in Hypoxia and Seizures.
Osama Al-Dalahmah, Alexander A Sosunov, Yu Sun, Yang Liu, Nacoya Madden, James E Goldman

Cells· January 2024

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Post-zygotic rescue of meiotic errors causes brain mosaicism and focal epilepsy.
Katherine E Miller, Adithe C Rivaldi, Noriyuki Shinagawa, Sahib Sran, Jason B Navarro, James E Goldman

Nat Genet· November 2023

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Multi-OMIC analysis of Huntington disease reveals a neuroprotective astrocyte state.
Fahad Paryani, Ji-Sun Kwon, Chris W Ng, Nacoya Madden, Kenneth Ofori, James E Goldman

bioRxiv· September 2023

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The stability of the myelinating oligodendrocyte transcriptome is regulated by the nuclear lamina.
Mathilde Pruvost, Julia Patzig, Camila Yattah, Ipek Selcen, Marylens Hernandez, James Goldman

Cell Rep· August 2023

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TMEM106B Puncta Is Increased in Multiple Sclerosis Plaques, and Reduced Protein in Mice Results in Delayed Lipid Clearance Following CNS Injury.
Bridget Shafit-Zagardo, Simone Sidoli, James E Goldman, Juwen C DuBois, John R Corboy

Cells· June 2023

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The link between SARS-CoV-2 related microglial reactivity and astrocyte pathology in the inferior olivary nucleus.
Nacoya Madden, Ying Zi Jessy Mei, Kelly Jakubiak, Juncheng Li, Gunnar Hargus, James E Goldman

Front Neurosci· June 2023

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Creating the Pick's disease International Consortium: Association study of H2 haplotype with risk of Pick's disease.
Rebecca R Valentino, William J Scotton, Shanu F Roemer, Tammaryn Lashley, Michael G Heckman, James E Goldman

medRxiv· April 2023

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COVID-19 induces CNS cytokine expression and loss of hippocampal neurogenesis.
Allison L Soung, Abigail Vanderheiden, Anna S Nordvig, Cheick A Sissoko, Peter Canoll, James E Goldman

Brain· December 2022

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Huntington disease oligodendrocyte maturation deficits revealed by single-nucleus RNAseq are rescued by thiamine-biotin supplementation.
Ryan G Lim, Osama Al-Dalahmah, Jie Wu, Maxwell P Gold, Jack C Reidling, James E Goldman

Nat Commun· December 2022

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Aβ Deposits in the Neocortex of Adult and Infant Hypoxic Brains, Including in Cases of COVID-19.
David S Priemer, Charles Harker Rhodes, Esma Karlovich, Daniel P Perl, James E Goldman

J Neuropathol Exp Neurol· November 2022

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Covid-19, nervous system pathology, and Parkinson's disease: Bench to bedside.
Aron Emmi, Iro Boura, Vanessa Raeder, Donna Mathew, David Sulzer, James E Goldman

Int Rev Neurobiol· October 2022

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Oligodendroglial macroautophagy is essential for myelin sheath turnover to prevent neurodegeneration and death.
Etan R Aber, Christopher J Griffey, Tim Davies, Alice M Li, Young Joo Yang, James E Goldman

Cell Rep· October 2022

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Somatic variants in diverse genes leads to a spectrum of focal cortical malformations.
Dulcie Lai, Meethila Gade, Edward Yang, Hyun Yong Koh, Jinfeng Lu, James E Goldman

Brain· August 2022

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Corticobasal Syndrome with TAR Binding Protein 43-Positive Oligodendrocyte Inclusions.
James E Goldman, Gregory A Rippon, Steven S Chin, Karen Marder

Mov Disord· July 2022

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Alzheimer Type I Astrocytes: Still Mysterious Cells.
James E Goldman

J Neuropathol Exp Neurol· July 2022

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Synaptic hyperexcitability of cytomegalic pyramidal neurons contributes to epileptogenesis in tuberous sclerosis complex.
Xiaoping Wu, Alexander A Sosunov, Wudu Lado, Jia Jie Teoh, Ahrom Ham, James E Goldman

Cell Rep· July 2022

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Non-cell-autonomous disruption of nuclear architecture as a potential cause of COVID-19-induced anosmia.
Marianna Zazhytska, Albana Kodra, Daisy A Hoagland, Justin Frere, John F Fullard, James E Goldman

Cell· March 2022

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Metabolic Enzyme Alterations and Astrocyte Dysfunction in a Murine Model of Alexander Disease With Severe Reactive Gliosis.
Michael R Heaven, Anthony W Herren, Daniel L Flint, Natasha L Pacheco, Jiangtao Li, James E Goldman

Mol Cell Proteomics· January 2022

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COVID-19 induces neuroinflammation and loss of hippocampal neurogenesis.
Robyn Klein, Allison Soung, Cheick Sissoko, Anna Nordvig, Peter Canoll, James Goldman

Res Sq· October 2021

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