Publications by authors named "James Greger"

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JNJ-78306358, a first-in-class bispecific T cell engaging antibody targeting CD3 and HLA-G.
Nataša Obermajer, Adam Zwolak, Kelly van de Ven, Shana Versmissen, Krista Menard, James G Greger

iScience· March 2025

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Safety and clinical activity of JNJ-78306358, a human leukocyte antigen-G (HLA-G) x CD3 bispecific antibody, for the treatment of advanced stage solid tumors.
Ravit Geva, Maria Vieito, Jorge Ramon, Ruth Perets, Manuel Pedregal, James G Greger

Cancer Immunol Immunother· August 2024

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A Phase I, Randomized, Multi-Dose Study to Evaluate the Enteric Selectivity and Safety of JAK Inhibitor, Lorpucitinib, in Healthy Participants.
Xuewen Ma, Gary Borzillo, Martine J Christine Kothe, Madhu Sanga, Gerald Chu, James G Greger

Clin Pharmacol Ther· May 2024

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Phase 1 Study of Safety and Preliminary Clinical Activity of JNJ-63898081, a PSMA and CD3 Bispecific Antibody, for Metastatic Castration-Resistant Prostate Cancer.
Emerson A Lim, Michael T Schweizer, Kim N Chi, Rahul Aggarwal, Neeraj Agarwal, James Greger

Clin Genitourin Cancer· June 2023

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First-in-human, open-label, phase 1/2 study of the monoclonal antibody programmed cell death protein-1 (PD-1) inhibitor cetrelimab (JNJ-63723283) in patients with advanced cancers.
Enriqueta Felip, Victor Moreno, Daniel Morgensztern, Giuseppe Curigliano, Piotr Rutkowski, James G Greger

Cancer Chemother Pharmacol· April 2022

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Pattern of rash, diarrhea, and hepatic toxicities secondary to lapatinib and their association with age and response to neoadjuvant therapy: analysis from the NeoALTTO trial.
Hatem A Azim, Dominique Agbor-Tarh, Ian Bradbury, Phuong Dinh, Jose Baselga, James G Greger

J Clin Oncol· December 2013

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Combinations of BRAF, MEK, and PI3K/mTOR inhibitors overcome acquired resistance to the BRAF inhibitor GSK2118436 dabrafenib, mediated by NRAS or MEK mutations.
James G Greger, Stephen D Eastman, Vivian Zhang, Maureen R Bleam, Ashley M Hughes

Mol Cancer Ther· April 2012

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Synergistic effects of foretinib with HER-targeted agents in MET and HER1- or HER2-coactivated tumor cells.
Li Liu, Hong Shi, Yuan Liu, Amber Anderson, John Peterson, James Greger

Mol Cancer Ther· March 2011

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Phosphorylation of MNAR promotes estrogen activation of phosphatidylinositol 3-kinase. Retraction.
James G. Greger, Natalie Fursov, Neil Cooch, Sean McLarney, Leonard P. Freedman

Mol Cell Biol· March 2010

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Novel mechanism of lapatinib resistance in HER2-positive breast tumor cells: activation of AXL.
Li Liu, James Greger, Hong Shi, Yuan Liu, Joel Greshock

Cancer Res· September 2009

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MNAR plays an important role in ERa activation of Src/MAPK and PI3K/Akt signaling pathways.
Boris J Cheskis, James Greger, Neil Cooch, Christopher McNally, Sean Mclarney

Steroids· October 2008

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Signaling by estrogens.
Boris J Cheskis, James G Greger, Sunil Nagpal, Leonard P Freedman

J Cell Physiol· December 2007

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Phosphorylation of MNAR promotes estrogen activation of phosphatidylinositol 3-kinase.
James G Greger, Natalie Fursov, Neil Cooch, Sean McLarney, Leonard P Freedman

Mol Cell Biol· March 2007

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High-frequency epigenetic repression and silencing of retroviruses can be antagonized by histone deacetylase inhibitors and transcriptional activators, but uniform reactivation in cell clones is restricted by additional mechanisms.
Richard A Katz, Emily Jack-Scott, Anna Narezkina, Ivan Palagin, Pamela Boimel, James G Greger

J Virol· March 2007

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Characterization of MNAR expression.
James G Greger, Yongjing Guo, Ruth Henderson, John F Ross, Boris J Cheskis

Steroids· April 2006

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Effects of cell cycle status on early events in retroviral replication.
Richard A Katz, James G Greger, Anna Marie Skalka

J Cell Biochem· April 2005

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The cellular protein daxx interacts with avian sarcoma virus integrase and viral DNA to repress viral transcription.
James G Greger, Richard A Katz, Alexander M Ishov, Gerd G Maul, Anna Marie Skalka

J Virol· April 2005

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Histone H2AX is phosphorylated at sites of retroviral DNA integration but is dispensable for postintegration repair.
René Daniel, Joseph Ramcharan, Emmy Rogakou, Konstantin D Taganov, James G Greger

J Biol Chem· October 2004

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Evidence that stable retroviral transduction and cell survival following DNA integration depend on components of the nonhomologous end joining repair pathway.
René Daniel, James G Greger, Richard A Katz, Konstantin D Taganov, Xiaoyun Wu

J Virol· August 2004

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Transduction of terminally differentiated neurons by avian sarcoma virus.
James G Greger, Richard A Katz, Konstantin Taganov, Glenn F Rall, Anna Marie Skalka

J Virol· May 2004

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Human immunodeficiency virus type 1 DNA nuclear import and integration are mitosis independent in cycling cells.
Richard A Katz, James G Greger, Pamela Boimel, Anna Marie Skalka

J Virol· December 2003

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Evidence that the retroviral DNA integration process triggers an ATR-dependent DNA damage response.
René Daniel, Gary Kao, Konstantin Taganov, James G Greger, Olga Favorova

Proc Natl Acad Sci U S A· April 2003

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Transduction of interphase cells by avian sarcoma virus.
Richard A Katz, James G Greger, Kristen Darby, Pamela Boimel, Glenn F Rall

J Virol· June 2002

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