Publications by authors named "James Hackland"

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Genome-wide CRISPR screen identifies Menin and SUZ12 as regulators of human developmental timing.
Nan Xu, Hyein S Cho, James O S Hackland, Silvia Benito-Kwiecinski, Nathalie Saurat

Nat Cell Biol· September 2025

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hPSC-derived sacral neural crest enables rescue in a severe model of Hirschsprung's disease.
Yujie Fan, James Hackland, Arianna Baggiolini, Lin Y Hung, Huiyong Zhao

Cell Stem Cell· March 2023

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Retinoic Acid Accelerates the Specification of Enteric Neural Progenitors from In-Vitro-Derived Neural Crest.
Thomas J R Frith, Antigoni Gogolou, James O S Hackland, Zoe A Hewitt, Harry D Moore

Stem Cell Reports· September 2020

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Top-Down Inhibition (TDi) and Baseline Activation (BLa): Controlling Signal Transduction When Endogenous Cytokines are Ruining Your Differentiation.
James Hackland

Curr Protoc Stem Cell Biol· December 2019

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Fully Defined and Xeno-Free Induction of hPSCs into Neural Crest Using Top-Down Inhibition of BMP Signaling.
James O S Hackland, Tom J R Frith, Peter W Andrews

Methods Mol Biol· August 2019

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WNT/β-catenin modulates the axial identity of embryonic stem cell-derived human neural crest.
Gustavo A Gomez, Maneeshi S Prasad, Man Wong, Rebekah M Charney, Patrick B Shelar, James O S Hackland

Development· August 2019

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FGF Modulates the Axial Identity of Trunk hPSC-Derived Neural Crest but Not the Cranial-Trunk Decision.
James O S Hackland, Patrick B Shelar, Nabjot Sandhu, Maneeshi S Prasad, Rebekah M Charney

Stem Cell Reports· May 2019

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Human axial progenitors generate trunk neural crest cells in vitro.
Thomas Jr Frith, Ilaria Granata, Matthew Wind, Erin Stout, Oliver Thompson, James Os Hackland

Elife· August 2018

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Identification and Single-Cell Functional Characterization of an Endodermally Biased Pluripotent Substate in Human Embryonic Stem Cells.
Thomas F Allison, Andrew J H Smith, Konstantinos Anastassiadis, Jackie Sloane-Stanley, Veronica Biga, James Hackland

Stem Cell Reports· June 2018

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Top-Down Inhibition of BMP Signaling Enables Robust Induction of hPSCs Into Neural Crest in Fully Defined, Xeno-free Conditions.
James O S Hackland, Tom J R Frith, Oliver Thompson, Ana Marin Navarro, Martin I Garcia-Castro

Stem Cell Reports· October 2017

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