Publications by authors named "James Ihle"

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An early onset progressive motor neuron disorder in Scyl1-deficient mice is associated with mislocalization of TDP-43.
Stephane Pelletier, Sebastien Gingras, Sherie Howell, Peter Vogel, James N Ihle

J Neurosci· November 2012

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Chromatin condensation via the condensin II complex is required for peripheral T-cell quiescence.
Jason S Rawlings, Martina Gatzka, Paul G Thomas, James N Ihle

EMBO J· January 2011

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Ars2 links the nuclear cap-binding complex to RNA interference and cell proliferation.
Joshua J Gruber, D Steven Zatechka, Leah R Sabin, Jeongsik Yong, Julian J Lum, James N Ihle

Cell· July 2009

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Negative regulation of Jak2 by its auto-phosphorylation at tyrosine 913 via the Epo signaling pathway.
Megumi Funakoshi-Tago, Kenji Tago, Tadashi Kasahara, Evan Parganas, James N Ihle

Cell Signal· November 2008

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Leukemia inhibitory factor regulates trophoblast giant cell differentiation via Janus kinase 1-signal transducer and activator of transcription 3-suppressor of cytokine signaling 3 pathway.
Yutaka Takahashi, Michiko Takahashi, Nick Carpino, Shiann-Tarng Jou, Jyh-Rong Chao, James N Ihle

Mol Endocrinol· July 2008

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Jak2 FERM domain interaction with the erythropoietin receptor regulates Jak2 kinase activity.
Megumi Funakoshi-Tago, Stéphane Pelletier, Hiroshi Moritake, Evan Parganas, James N Ihle

Mol Cell Biol· March 2008

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Hax1-mediated processing of HtrA2 by Parl allows survival of lymphocytes and neurons.
Jyh-Rong Chao, Evan Parganas, Kelli Boyd, Cheol Yi Hong, Joseph T Opferman, James N Ihle

Nature· March 2008

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Characterization of a family of novel cysteine- serine-rich nuclear proteins (CSRNP).
Sébastien Gingras, Stéphane Pelletier, Kelli Boyd, James N Ihle

PLoS One· August 2007

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Jak2: normal function and role in hematopoietic disorders.
James N Ihle, D Gary Gilliland

Curr Opin Genet Dev· February 2007

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Two domains of the erythropoietin receptor are sufficient for Jak2 binding/activation and function.
Stéphane Pelletier, Sébastien Gingras, Megumi Funakoshi-Tago, Sherié Howell, James N Ihle

Mol Cell Biol· November 2006

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Receptor specific downregulation of cytokine signaling by autophosphorylation in the FERM domain of Jak2.
Megumi Funakoshi-Tago, Stephane Pelletier, Tadashi Matsuda, Evan Parganas, James N Ihle

EMBO J· October 2006

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A role for STAT5A/B in protection of peripheral T-lymphocytes from postactivation apoptosis: insights from gene expression profiling.
Martina Gatzka, Roland Piekorz, Richard Moriggl, Jason Rawlings, James N Ihle

Cytokine· May 2006

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Trophoblast stem cells rescue placental defect in SOCS3-deficient mice.
Yutaka Takahashi, Massimo Dominici, John Swift, Cristie Nagy, James N Ihle

J Biol Chem· April 2006

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Divergent mechanisms utilized by SOCS3 to mediate interleukin-10 inhibition of tumor necrosis factor alpha and nitric oxide production by macrophages.
Pooran Qasimi, Andrew Ming-Lum, Ali Ghanipour, Christopher J Ong, Michael E Cox, James Ihle

J Biol Chem· March 2006

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Role of erythropoietin receptor signaling in Friend virus-induced erythroblastosis and polycythemia.
Ji Zhang, Mindy S Randall, Melanie R Loyd, Weimin Li, Rachel L Schweers, James N Ihle

Blood· January 2006

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Regulation of interleukin 7-dependent immunoglobulin heavy-chain variable gene rearrangements by transcription factor STAT5.
Eric Bertolino, Karen Reddy, Kay L Medina, Evan Parganas, James Ihle

Nat Immunol· August 2005

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Evi-1 expression in Xenopus.
Paul E Mead, Evan Parganas, Shiro Ohtsuka, Kazuhiro Morishita, Laura Gamer, James N Ihle

Gene Expr Patterns· June 2005

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Regulation of progesterone levels during pregnancy and parturition by signal transducer and activator of transcription 5 and 20alpha-hydroxysteroid dehydrogenase.
Roland P Piekorz, Sébastien Gingras, Angelika Hoffmeyer, James N Ihle, Yacob Weinstein

Mol Endocrinol· February 2005

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Stat5 tetramer formation is associated with leukemogenesis.
Richard Moriggl, Veronika Sexl, Lukas Kenner, Christopher Duntsch, Katharina Stangl, James N Ihle

Cancer Cell· January 2005

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Re-examination of the role of suppressor of cytokine signaling 1 (SOCS1) in the regulation of toll-like receptor signaling.
Sébastien Gingras, Evan Parganas, Antoine de Pauw, James N Ihle, Peter J Murray

J Biol Chem· December 2004

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Determination of the transphosphorylation sites of Jak2 kinase.
Tadashi Matsuda, Jian Feng, Bruce A Witthuhn, Yuichi Sekine, James N Ihle

Biochem Biophys Res Commun· December 2004

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The centrosomal, putative tumor suppressor protein TACC2 is dispensable for normal development, and deficiency does not lead to cancer.
Michael M Schuendeln, Roland P Piekorz, Christian Wichmann, Youngsoo Lee, Peter J McKinnon, James N Ihle

Mol Cell Biol· July 2004

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Absence of an essential role for thymic stromal lymphopoietin receptor in murine B-cell development.
Nick Carpino, William E Thierfelder, Ming-shi Chang, Chris Saris, Steven J Turner, James N Ihle

Mol Cell Biol· March 2004

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Regulation of ZAP-70 activation and TCR signaling by two related proteins, Sts-1 and Sts-2.
Nick Carpino, Steve Turner, Divya Mekala, Yutaka Takahashi, Heesuk Zang, James N Ihle

Immunity· January 2004

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Puma is an essential mediator of p53-dependent and -independent apoptotic pathways.
John R Jeffers, Evan Parganas, Youngsoo Lee, Chunying Yang, JinLing Wang, James N Ihle

Cancer Cell· October 2003

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