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Publications by authors named "James Kinkead"

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Fast acting allosteric phosphofructokinase inhibitors block trypanosome glycolysis and cure acute African trypanosomiasis in mice.
Iain W McNae, James Kinkead, Divya Malik, Li-Hsuan Yen, Martin K Walker

Nat Commun· February 2021


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Biochemical and transcript level differences between the three human phosphofructokinases show optimisation of each isoform for specific metabolic niches.
Peter M Fernandes, James Kinkead, Iain McNae, Paul A M Michels, Malcolm D Walkinshaw

Biochem J· November 2020


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Kinetic and structural studies of Trypanosoma and Leishmania phosphofructokinases show evolutionary divergence and identify AMP as a switch regulating glycolysis versus gluconeogenesis.
Peter M Fernandes, James Kinkead, Iain W McNae, Monserrat Vásquez-Valdivieso, Martin A Wear

FEBS J· July 2020


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The kinetic characteristics of human and trypanosomatid phosphofructokinases for the reverse reaction.
Peter M Fernandes, James Kinkead, Iain W McNae, Frédéric Bringaud, Paul A M Michels

Biochem J· January 2019


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