Publications by authors named "James Knowles"

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Mapping the genetic landscape across 14 psychiatric disorders.
Andrew D Grotzinger, Josefin Werme, Wouter J Peyrot, Oleksandr Frei, Christiaan de Leeuw, James A Knowles

Nature· December 2025

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Moving beyond symptom subtypes: testing a common dimension of lifetime OCD symptoms.
Abel S Mathew, Sarah L Garnaat, David R Strong, Nicole C R McLaughlin, Kathleen D Askland, James A Knowles

CNS Spectr· November 2025

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Whole-genome sequence-based association analysis of African American individuals with bipolar disorder and schizophrenia.
Runjia Li, Sarah A Gagliano Taliun, Kevin Liao, Matthew Flickinger, Janet L Sobell, James Knowles

HGG Adv· August 2025

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Psychiatric disorders converge on common pathways but diverge in cellular context, spatial distribution, and directionality of genetic effects.
Worrawat Engchuan, Omar Shanta, Kuldeep Kumar, Jeffrey R MacDonald, Bhooma Thiruvahindrapuram, James A Knowles

medRxiv· July 2025

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A cross-disorder analysis of CNVs finds novel loci and dose-dependent relationships of genes to psychiatric traits.
Omar Shanta, Marieke Klein, Molly Sacks, Jeffrey R MacDonald, Adam Maihofer, James A Knowles

medRxiv· July 2025

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Genome-wide analyses identify 30 loci associated with obsessive-compulsive disorder.
Nora I Strom, Zachary F Gerring, Marco Galimberti, Dongmei Yu, Matthew W Halvorsen, James A Knowles

Nat Genet· June 2025

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Immune, Developmental, and Synaptic Pathways Define Bipolar Disorder Clinical Heterogeneity.
Tracey van der Veen, Markos Tesfaye, Jessica Mei Kay Yang, Toni Boltz, Friederike S David, James A Knowles

medRxiv· June 2025

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Genome-wide analyses identify 30 loci associated with obsessive-compulsive disorder.
Nora I Strom, Zachary F Gerring, Marco Galimberti, Dongmei Yu, Matthew W Halvorsen, James A Knowles

medRxiv· April 2025

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Evaluation of imputation performance of multiple reference panels in a Pakistani population.
Jiayi Xu, Dongjing Liu, Arsalan Hassan, Giulio Genovese, Alanna C Cote, James A Knowles

HGG Adv· April 2025

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Genomics yields biological and phenotypic insights into bipolar disorder.
Kevin S O'Connell, Maria Koromina, Tracey van der Veen, Toni Boltz, Friederike S David, James A Knowles

Nature· March 2025

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Consistent supply of global plasma for global patients.
Michelle Fransen, Toby Simon, James Knowles, Joshua Penrod

Vox Sang· February 2025

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Whole genome sequence-based association analysis of African American individuals with bipolar disorder and schizophrenia.
Runjia Li, Sarah A Gagliano Taliun, Kevin Liao, Matthew Flickinger, Janet L Sobell, James Knowles

medRxiv· February 2025

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Identifying genetic differences between bipolar disorder and major depression through multiple genome-wide association analyses.
Georgia Panagiotaropoulou, Kajsa-Lotta Georgii Hellberg, Jonathan R I Coleman, Darsol Seok, Janos Kalman, James A Knowles

Br J Psychiatry· February 2025

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The Landscape of Shared and Divergent Genetic Influences across 14 Psychiatric Disorders.
Andrew D Grotzinger, Josefin Werme, Wouter J Peyrot, Oleksandr Frei, Christiaan de Leeuw, James A Knowles

medRxiv· January 2025

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Identifying genetic differences between bipolar disorder and major depression through multiple GWAS.
Georgia Panagiotaropoulou, Kajsa-Lotta Georgii Hellberg, Jonathan R I Coleman, Darsol Seok, Janos Kalman, James A Knowles

medRxiv· January 2024

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Cell Type Catalog of Middle Turbinate Epithelium ().
Fasil Mathews, Victoria Sook Keng Tung, Robert Foronjy, Marina Boruk, James A Knowles

OTO Open· December 2023

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Evaluation of imputation performance of multiple reference panels in a Pakistani population.
Jiayi Xu, Dongjing Liu, Arsalan Hassan, Giulio Genovese, Alanna C Cote, James A Knowles

medRxiv· December 2023

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Cultured Mesenchymal Cells from Nasal Turbinate as a Cellular Model of the Neurodevelopmental Component of Schizophrenia Etiology.
Victoria Sook Keng Tung, Fasil Mathews, Marina Boruk, Gabrielle Suppa, Robert Foronjy, James A Knowles

Int J Mol Sci· October 2023

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Mice lacking Ptprd exhibit deficits in goal-directed behavior and female-specific impairments in sensorimotor gating.
Emily V Ho, Amanda Welch, Summer L Thompson, James A Knowles, Stephanie C Dulawa

PLoS One· May 2023

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Study protocol of DIVERGE, the first genetic epidemiological study of major depressive disorder in Pakistan.
Maria Valkovskaya, Arsalan Hassan, Eirini Zartaloudi, Fahad Hussain, Muhammad Umar, James A Knowles

Psychiatr Genet· April 2023

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Cultured Mesenchymal Cells from Nasal Turbinate as a Cellular Model of the Neurodevelopmental Component of Schizophrenia Etiology.
Victoria Sook Keng Tung, Fasil Mathews, Marina Boruk, Gabrielle Suppa, Robert Foronjy, James A Knowles

bioRxiv· March 2023

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Fracture load of zirconia crowns based on preparation and cement type.
John S Jenista, Wyeth L Hoopes, James F Knowles, Kraig S Vandewalle

Gen Dent· August 2022

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Mapping genomic loci implicates genes and synaptic biology in schizophrenia.
Vassily Trubetskoy, Antonio F Pardiñas, Ting Qi, Georgia Panagiotaropoulou, Swapnil Awasthi, James A Knowles

Nature· April 2022

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What Have We Learned About the Genetics of Obsessive-Compulsive and Related Disorders in Recent Years?
Manuel Mattheisen, Michele T Pato, Carlos N Pato, James A Knowles

Focus (Am Psychiatr Publ)· October 2021

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