Publications by authors named "James Lally"

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Dual inhibition of ACLY and ACSS2 by EVT0185 reduces steatosis, hepatic stellate cell activation, and fibrosis in mouse models of MASH.
Fiorella Di Pastena, Jaya Gautam, James S V Lally, Russta Fayyazi, Estelle Grasset

Cell Metab· January 2026

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ACLY inhibition promotes tumour immunity and suppresses liver cancer.
Jaya Gautam, Jianhan Wu, James S V Lally, Jamie D McNicol, Russta Fayyazi

Nature· September 2025

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Salsalate improves the anti-tumor efficacy of lenvatinib in MASH-driven hepatocellular carcinoma.
Evangelia E Tsakiridis, Elham Ahmadi, Jaya Gautam, Yi Ran Hannah She, Russta Fayyazi, James S V Lally

JHEP Rep· May 2025

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Prevalence of dry eye disease in the low vision population at the University of Colorado.
Kaleb Abbott, Kara S Hanson, James Lally

J Optom· March 2024

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Fatty Acids Increase GDF15 and Reduce Food Intake Through a GFRAL Signaling Axis.
Dongdong Wang, Maria Joy Therese Jabile, Junfeng Lu, Logan K Townsend, Celina M Valvano, James S V Lally

Diabetes· January 2024

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Combination of an ACLY inhibitor with a GLP-1R agonist exerts additive benefits on nonalcoholic steatohepatitis and hepatic fibrosis in mice.
Eric M Desjardins, Jianhan Wu, Declan C T Lavoie, Elham Ahmadi, Logan K Townsend, James S V Lally

Cell Rep Med· September 2023

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GDF15 promotes weight loss by enhancing energy expenditure in muscle.
Dongdong Wang, Logan K Townsend, Geneviève J DesOrmeaux, Sara M Frangos, Battsetseg Batchuluun, James S V Lally

Nature· July 2023

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People living in homeless hostels: a survey of health and care needs.
Caroline Shulman, J J Nadicksbernd, Theresa Nguyen, Erin Raquel Fantoni, James Lally

Clin Med (Lond)· July 2023

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Metformin-induced reductions in tumor growth involves modulation of the gut microbiome.
Lindsay A Broadfield, Amna Saigal, Jake C Szamosi, Joanne A Hammill, Ksenia Bezverbnaya, James S V Lally

Mol Metab· July 2022

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Inhibition of ATP-citrate lyase improves NASH, liver fibrosis, and dyslipidemia.
Marisa R Morrow, Battsetseg Batchuluun, Jianhan Wu, Elham Ahmadi, Julie M Leroux, James S V Lally

Cell Metab· June 2022

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Co-overexpression of CD36 and FABPpm increases fatty acid transport additively, not synergistically, within muscle.
Graham P Holloway, James G Nickerson, James S V Lally, Heather L Petrick, Kaitlyn M J H Dennis

Am J Physiol Cell Physiol· March 2022

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The pesticide chlorpyrifos promotes obesity by inhibiting diet-induced thermogenesis in brown adipose tissue.
Bo Wang, Evangelia E Tsakiridis, Shuman Zhang, Andrea Llanos, Eric M Desjardins, James S V Lally

Nat Commun· August 2021

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The SGLT2 inhibitor canagliflozin suppresses lipid synthesis and interleukin-1 beta in ApoE deficient mice.
Emily A Day, Rebecca J Ford, Jessie H Lu, Rachel Lu, Lucie Lundenberg, James S V Lally

Biochem J· June 2020

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GATA-1: A potential novel biomarker for the differentiation of essential thrombocythemia and myelofibrosis.
James Lally, Kristian Boasman, Lilia Brown, Vincenzo Martinelli, Ilaria Cappuccio

J Thromb Haemost· June 2019

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Salicylate enhances the response of prostate cancer to radiotherapy.
Lindsay A Broadfield, Katarina Marcinko, Evangelia Tsakiridis, Panayiotis G Zacharidis, Linda Villani, James S V Lally

Prostate· April 2019

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Inhibition of Acetyl-CoA Carboxylase by Phosphorylation or the Inhibitor ND-654 Suppresses Lipogenesis and Hepatocellular Carcinoma.
James S V Lally, Sarani Ghoshal, Danielle K DePeralta, Omeed Moaven, Lan Wei

Cell Metab· January 2019

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The role of AMP-activated protein kinase in the expression of the dystrophin-associated protein complex in skeletal muscle.
Athan G Dial, Paul Rooprai, James S Lally, Adam L Bujak, Gregory R Steinberg

FASEB J· June 2018

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Treatment of nonalcoholic fatty liver disease: role of AMPK.
Brennan K Smith, Katarina Marcinko, Eric M Desjardins, James S Lally, Rebecca J Ford

Am J Physiol Endocrinol Metab· October 2016

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Extremely rapid increase in fatty acid transport and intramyocellular lipid accumulation but markedly delayed insulin resistance after high fat feeding in rats.
Arend Bonen, Swati S Jain, Laelie A Snook, Xiao-Xia Han, Yuko Yoshida, James S Lally

Diabetologia· October 2015

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The AMPK activator R419 improves exercise capacity and skeletal muscle insulin sensitivity in obese mice.
Katarina Marcinko, Adam L Bujak, James S V Lally, Rebecca J Ford, Tammy H Wong

Mol Metab· September 2015

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AMPK deficiency in cardiac muscle results in dilated cardiomyopathy in the absence of changes in energy metabolism.
Miranda M Sung, Beshay N Zordoky, Adam L Bujak, James S V Lally, David Fung

Cardiovasc Res· July 2015

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Skeletal muscle ACC2 S212 phosphorylation is not required for the control of fatty acid oxidation during exercise.
Hayley M O'Neill, James S Lally, Sandra Galic, Thomas Pulinilkunnil, Rebecca J Ford

Physiol Rep· July 2015

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AMPK activation of muscle autophagy prevents fasting-induced hypoglycemia and myopathy during aging.
Adam L Bujak, Justin D Crane, James S Lally, Rebecca J Ford, Sally J Kang

Cell Metab· June 2015

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Skeletal muscle AMPK is essential for the maintenance of FNDC5 expression.
James S V Lally, Rebecca J Ford, Jasper Johar, Justin D Crane, Bruce E Kemp

Physiol Rep· May 2015

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The hill battles of Khe Sanh: a marine corps doctor remembers.
James F Lally

Del Med J· December 2014

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