Publications by authors named "James Mu"

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Hub disruption in HIV disease and cocaine use: A connectomics analysis of brain function.
Kareem Al-Khalil, Ryan P Bell, Sheri L Towe, Jessica R Cohen, Syam Gadde, James Mu

Drug Alcohol Depend· October 2024

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Author Correction: Functionally selective signaling and broad metabolic benefits by novel insulin receptor partial agonists.
Margaret Wu, Ester Carballo-Jane, Haihong Zhou, Peter Zafian, Ge Dai, James Mu

Nat Commun· January 2024

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Discovery of Insulin Receptor Partial Agonists MK-5160 and MK-1092 as Novel Basal Insulins with Potential to Improve Therapeutic Index.
Dmitri A Pissarnitski, Ahmet Kekec, Lin Yan, Yuping Zhu, Danqing D Feng, James Mu

J Med Chem· April 2022

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Functionally selective signaling and broad metabolic benefits by novel insulin receptor partial agonists.
Margaret Wu, Ester Carballo-Jane, Haihong Zhou, Peter Zafian, Ge Dai, James Mu

Nat Commun· February 2022

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High Resolution Episcopic Microscopy for Qualitative and Quantitative Data in Phenotyping Altered Embryos and Adult Mice Using the New "Histo3D" System.
Olivia Wendling, Didier Hentsch, Hugues Jacobs, Nicolas Lemercier, Serge Taubert, James Mu

Biomedicines· July 2021

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In Situ Forming Injectable Thermoresponsive Hydrogels for Controlled Delivery of Biomacromolecules.
Kingshuk Dutta, Ritam Das, Jing Ling, Rafael Mayoral Monibas, Ester Carballo-Jane, James Mu

ACS Omega· July 2020

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Restoration of insulin receptor improves diabetic phenotype in T2DM mice.
Yichen Wang, Heather Zhou, Oksana Palyha, James Mu

JCI Insight· August 2019

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Erratum. Engineering Glucose Responsiveness Into Insulin. Diabetes 2018;67:299-308.
Niels C Kaarsholm, Songnian Lin, Lin Yan, Theresa Kelly, Margaret van Heek, James Mu

Diabetes· May 2018

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Engineering Glucose Responsiveness Into Insulin.
Niels C Kaarsholm, Songnian Lin, Lin Yan, Theresa Kelly, Margaret van Heek, James Mu

Diabetes· February 2018

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A glucose-responsive insulin therapy protects animals against hypoglycemia.
Ruojing Yang, Margaret Wu, Songnian Lin, Ravi P Nargund, Xinghai Li, James Mu

JCI Insight· January 2018

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Potentiation of insulin-mediated glucose lowering without elevated hypoglycemia risk by a small molecule insulin receptor modulator.
Margaret Wu, Ge Dai, Jun Yao, Scott Hoyt, Liangsu Wang, James Mu

PLoS One· February 2016

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Downstream signaling pathways in mouse adipose tissues following acute in vivo administration of fibroblast growth factor 21.
Eric S Muise, Sandra Souza, An Chi, Yejun Tan, Xuemei Zhao, James Mu

PLoS One· June 2014

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Anti-diabetic efficacy and impact on amino acid metabolism of GRA1, a novel small-molecule glucagon receptor antagonist.
James Mu, Sajjad A Qureshi, Edward J Brady, Eric S Muise, Mari Rios Candelore

PLoS One· May 2013

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The glucagon receptor is involved in mediating the body weight-lowering effects of oxyntomodulin.
Jennifer R Kosinski, James Hubert, Paul E Carrington, Gary G Chicchi, James Mu

Obesity (Silver Spring)· August 2012

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FGF21 analogs of sustained action enabled by orthogonal biosynthesis demonstrate enhanced antidiabetic pharmacology in rodents.
James Mu, Jason Pinkstaff, Zhihua Li, Lillian Skidmore, Nina Li

Diabetes· February 2012

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Inhibition of DPP-4 with sitagliptin improves glycemic control and restores islet cell mass and function in a rodent model of type 2 diabetes.
James Mu, Aleksandr Petrov, George J Eiermann, John Woods, Yun-Ping Zhou

Eur J Pharmacol· November 2009

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Adipose fibroblast growth factor 21 is up-regulated by peroxisome proliferator-activated receptor gamma and altered metabolic states.
Eric S Muise, Barbara Azzolina, David W Kuo, Mohamed El-Sherbeini, Yejun Tan, James Mu

Mol Pharmacol· August 2008

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PANIC-ATTAC: a mouse model for inducible and reversible beta-cell ablation.
Zhao V Wang, James Mu, Todd D Schraw, Laurent Gautron, Joel K Elmquist

Diabetes· August 2008

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Chronic inhibition of dipeptidyl peptidase-4 with a sitagliptin analog preserves pancreatic beta-cell mass and function in a rodent model of type 2 diabetes.
James Mu, John Woods, Yun-Ping Zhou, Ranabir Sinha Roy, Zhihua Li

Diabetes· June 2006

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AMP-activated protein kinase induces a p53-dependent metabolic checkpoint.
Russell G Jones, David R Plas, Sara Kubek, Monica Buzzai, James Mu

Mol Cell· April 2005

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AMP kinase is not required for the GLUT4 response to exercise and denervation in skeletal muscle.
Burton F Holmes, David B Lang, Morris J Birnbaum, James Mu, G Lynis Dohm

Am J Physiol Endocrinol Metab· October 2004

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The PP2A-associated protein alpha4 is an essential inhibitor of apoptosis.
Mei Kong, Casey J Fox, James Mu, Laura Solt, Anne Xu

Science· October 2004

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AMP-activated protein kinase mediates ischemic glucose uptake and prevents postischemic cardiac dysfunction, apoptosis, and injury.
Raymond R Russell, Ji Li, David L Coven, Marc Pypaert, Christoph Zechner, James Mu

J Clin Invest· August 2004

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AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus.
Yasuhiko Minokoshi, Thierry Alquier, Noboru Furukawa, Yong-Bum Kim, Anna Lee, James Mu

Nature· April 2004

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Isoform-specific regulation of insulin-dependent glucose uptake by Akt/protein kinase B.
Sun Sik Bae, Han Cho, James Mu, Morris J Birnbaum

J Biol Chem· December 2003

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