Publications by authors named "James Mule"

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Case Report: Durable response to tumor-infiltrating lymphocyte therapy in a patient with metastatic melanoma and chronic lymphocytic leukemia/small lymphocytic lymphoma.
Lilit Karapetyan, Joel Kuriakose, Matthew C Perez, Johannes R Ali, MacLean S Hall

Front Immunol· December 2025

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Safety and efficacy of tumor-infiltrating lymphocyte (TIL) therapy with reduced-dose lymphodepleting conditioning in high-risk metastatic melanoma patients.
Lilit Karapetyan, Joel Kuriakose, Elizabeth DiMaggio, Kimberly Ward, Jamie Chau

Transplant Cell Ther· December 2025

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The Myeloid Biomarker Drives an Immunosuppressive Microenvironment in Glioblastoma via Activation of the PGE2 Signaling Axis.
Jianan Chen, Qiong Wu, Anders E Berglund, Robert J Macaulay, James J Mulé

Int J Mol Sci· December 2025

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Chemokine/cytokine-releasing biomaterials induce in situ tertiary lymphoid-like structures and enhance antitumor immunity.
Rana Falahat, James J Mulé

Proc Natl Acad Sci U S A· November 2025

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Expression Marks Chemokine (C-C Motif) Ligand-Enriched Macrophage-Tumor Interactions in the Glioblastoma Microenvironment.
Jianan Chen, Qiong Wu, Anders E Berglund, Robert J Macaulay, James J Mulé

Cancers (Basel)· October 2025

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Tumor-Associated Macrophages in Glioblastoma: Mechanisms of Tumor Progression and Therapeutic Strategies.
Jianan Chen, Qiong Wu, Anders E Berglund, Robert J Macaulay, James J Mulé

Cells· September 2025

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Facts and Hopes: Toward the Next Quantum Leap in Melanoma.
Keith T Flaherty, Andrew E Aplin, Michael A Davies, Nir Hacohen, Meenhard Herlyn

Clin Cancer Res· July 2025

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Identification of an Immune-Related Gene Signature for Prognostic Prediction in Glioblastoma: Insights from Integrated Bulk and Single-Cell RNA Sequencing.
Jianan Chen, Qiong Wu, Anders E Berglund, Robert J Macaulay, James J Mulé

Cancers (Basel)· May 2025

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CD40L stimulates tumor-infiltrating B-cells and improves ex vivo TIL expansion.
Renata Ariza Marques Rossetti, Leticia Tordesillas, Matthew S Beatty, Junior Cianne, Elena Martinez Planes

J Immunother Cancer· April 2025

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Evaluating the Radiation Sensitivity Index and 12-Chemokine Gene Expression Signature for Clinical Use in a CLIA Laboratory.
Anders E Berglund, John Puskas, Sean J Yoder, Andrew T Smith, Douglas C Marchion

Cancer Res Commun· March 2025

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Targeting MARCO in combination with anti-CTLA-4 leads to enhanced melanoma regression and immune cell infiltration via macrophage reprogramming.
Hidenori Takahashi, Patricio Perez-Villarroel, Rana Falahat, James J Mulé

J Immunother Cancer· March 2025

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Oncolytic immunotherapy with nivolumab in muscle-invasive bladder cancer: a phase 1b trial.
Roger Li, Nancy Y Villa, Xiaoqing Yu, Joseph O Johnson, Gustavo Borjas

Nat Med· January 2025

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Enabling next-generation engineered TCR-T therapies based on high-throughput TCR discovery from diagnostic tumor biopsies.
Thomas Kuilman, Deborah S Schrikkema, Jules Gadiot, Raquel Gomez-Eerland, Laura Bies

Nat Commun· January 2025

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Increased spatial coupling of integrin and collagen IV in the immunoresistant clear-cell renal-cell carcinoma tumor microenvironment.
Alex C Soupir, Mitchell T Hayes, Taylor C Peak, Oscar Ospina, Nicholas H Chakiryan

Genome Biol· December 2024

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Differences in the pathological, transcriptomic, and prognostic implications of lymphoid structures between primary and metastatic cutaneous melanomas.
Lilit Karapetyan, Aofei Li, Danielle Vargas De Stefano, Hassan M Abushukair, Ayah N Al-Bzour, James J Mule

J Immunother Cancer· November 2024

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Evaluating the Radiation Sensitivity Index and 12-chemokine gene expression signature for clinical use in a CLIA laboratory.
Anders Berglund, John Puskas, Sean Yoder, Andrew T Smith, Douglas C Marchion

bioRxiv· September 2024

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Tumor-infiltrating lymphocytes: A new hope.
Amod A Sarnaik, Patrick Hwu, James J Mulé, Shari Pilon-Thomas

Cancer Cell· August 2024

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Epigenome-wide association study of prostate cancer in African American men identified differentially methylated genes.
Anders Berglund, Kosj Yamoah, Steven A Eschrich, Rana Falahat, James J Mulé

Cancer Med· August 2024

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Increased spatial coupling of integrin and collagen IV in the immunoresistant clear cell renal cell carcinoma tumor microenvironment.
Alex C Soupir, Mitchell T Hayes, Taylor C Peak, Oscar Ospina, Nicholas H Chakiryan

bioRxiv· November 2023

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Neoantigen-specific CD4 tumor-infiltrating lymphocytes are potent effectors identified within adoptive cell therapy products for metastatic melanoma patients.
MacLean S Hall, Jamie K Teer, Xiaoqing Yu, Holly Branthoover, Sebastian Snedal, James J Mule

J Immunother Cancer· October 2023

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Geospatial characterization of immune cell distributions and dynamics across the microenvironment in clear cell renal cell carcinoma.
Nicholas H Chakiryan, Youngchul Kim, Anders Berglund, Andrew Chang, Gregory J Kimmel

J Immunother Cancer· April 2023

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Epigenetic state determines the in vivo efficacy of STING agonist therapy.
Rana Falahat, Anders Berglund, Patricio Perez-Villarroel, Ryan M Putney, Imene Hamaidi

Nat Commun· March 2023

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Dichotomous Nitric Oxide-Dependent Post-Translational Modifications of STAT1 Are Associated with Ipilimumab Benefits in Melanoma.
Saurabh K Garg, James Sun, Youngchul Kim, Junmin Whiting, Amod Sarnaik

Cancers (Basel)· March 2023

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Combination Nivolumab, CD137 Agonism, and Adoptive Cell Therapy with Tumor-Infiltrating Lymphocytes for Patients with Metastatic Melanoma.
MacLean S Hall, John E Mullinax, Cheryl A Cox, Amy M Hall, Matthew S Beatty

Clin Cancer Res· December 2022

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The Radiosensitivity Index Gene Signature Identifies Distinct Tumor Immune Microenvironment Characteristics Associated With Susceptibility to Radiation Therapy.
G Daniel Grass, Juan C L Alfonso, Eric Welsh, Kamran A Ahmed, Jamie K Teer

Int J Radiat Oncol Biol Phys· July 2022

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