Publications by authors named "James R Mitchell"

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Endogenous hydrogen sulfide production is essential for dietary restriction benefits.
Christopher Hine, Eylul Harputlugil, Yue Zhang, Christoph Ruckenstuhl, Byung Cheon Lee, Lear Brace, Alban Longchamp, Jose H Treviño-Villarreal, Pedro Mejia, C Keith Ozaki

Cell· January 2015

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Angiogenesis-independent VEGF signaling enhances exercise capacity by increasing fat oxidation in mice fed sulfur amino acid-restricted diets.
Charlotte G Mann, Michael R MacArthur, Jing Zhang, Songlin Gong, Jenna E AbuSalim, James R Mitchell, Sarah J Mitchell

iScience· December 2025

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Correction to: Lifespan effects in male UM‑HET3 mice treated with sodium thiosulfate, 16-hydroxyestradiol, and late‑start canagliflozin.
Richard A Miller, David E Harrison, Gino A Cortopassi, Ishmael Dehghan, Elizabeth Fernandez, James R Mitchell

Geroscience· October 2025

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Correction to: Lifespan effects in male UM‑HET3 mice treated with sodium thiosulfate, 16‑hydroxyestriol, and late‑start canagliflozin.
Richard A Miller, David E Harrison, Gino A Cortopassi, Ishmael Dehghan, Elizabeth Fernandez, James R Mitchell

Geroscience· August 2025

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Preoperative methionine restriction induces perivascular adipose tissue browning and improves vein graft remodeling in male mice.
Peter Kip, Thijs J Sluiter, Michael R MacArthur, Ming Tao, Nicky Kruit, Sarah J Mitchell, James R Mitchell

Nat Commun· November 2024

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Lifespan effects in male UM-HET3 mice treated with sodium thiosulfate, 16-hydroxyestriol, and late-start canagliflozin.
Richard A Miller, David E Harrison, Gino A Cortopassi, Ishmael Dehghan, Elizabeth Fernandez, James R Mitchell

Geroscience· October 2024

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Sulfur Amino Acid Restriction Enhances Exercise Capacity in Mice by Boosting Fat Oxidation in Muscle.
Charlotte G Mann, Michael R MacArthur, Jing Zhang, Songlin Gong, Jenna E AbuSalim, James R Mitchell, Sarah J Mitchell

bioRxiv· July 2024

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TIME-seq reduces time and cost of DNA methylation measurement for epigenetic clock construction.
Patrick T Griffin, Alice E Kane, Alexandre Trapp, Jien Li, Matthew Arnold, Sarah J Mitchell, James R Mitchell

Nat Aging· February 2024

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Short-term Pre-operative Methionine Restriction Induces Browning of Perivascular Adipose Tissue and Improves Vein Graft Remodeling in Mice.
Peter Kip, Thijs J Sluiter, Michael R MacArthur, Ming Tao, Jonathan Jung, Sarah J Mitchell, James R Mitchell

bioRxiv· November 2023

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Cystathionine-γ-lyase overexpression modulates oxidized nicotinamide adenine dinucleotide biosynthesis and enhances neovascularization.
Kevin Kiesworo, Michael R MacArthur, Peter Kip, Thomas Agius, Diane Macabrey, James R Mitchell, Sarah J Mitchell

JVS Vasc Sci· January 2023

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Multiomics assessment of dietary protein titration reveals altered hepatic glucose utilization.
Michael R MacArthur, Sarah J Mitchell, Katia S Chadaideh, J Humberto Treviño-Villarreal, Jonathan Jung, James R Mitchell

Cell Rep· August 2022

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The non-essential TSC complex component TBC1D7 restricts tissue mTORC1 signaling and brain and neuron growth.
Sandra Schrötter, Christopher J Yuskaitis, Michael R MacArthur, Sarah J Mitchell, Aaron M Hosios, James R Mitchell

Cell Rep· May 2022

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Sulfur Amino Acid Supplementation Abrogates Protective Effects of Caloric Restriction for Enhancing Bone Marrow Regrowth Following Ionizing Radiation.
Christopher Hine, J Humberto Treviño-Villarreal, Pedro Mejia, Alban Longchamp, Lear E Brace, Sarah J Mitchell, James R Mitchell

Nutrients· April 2022

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Short-Term Ketogenic Diet Induces a Molecular Response That Is Distinct From Dietary Protein Restriction.
Krystle C Kalafut, Sarah J Mitchell, Michael R MacArthur, James R Mitchell

Front Nutr· March 2022

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Intracellular HS production is an autophagy-dependent adaptive response to DNA damage.
Xiaofeng Jiang, Michael R MacArthur, J Humberto Treviño-Villarreal, Peter Kip, C Keith Ozaki, Sarah J Mitchell, James R Mitchell

Cell Chem Biol· December 2021

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Short-Term Pre-Operative Protein Caloric Restriction in Elective Vascular Surgery Patients: A Randomized Clinical Trial.
Peter Kip, Thijs J Sluiter, Jodene K Moore, Abby Hart, Jack Ruske, Sarah J Mitchell, James R Mitchell

Nutrients· November 2021

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Neurovascular dysfunction and neuroinflammation in a Cockayne syndrome mouse model.
Gustavo Satoru Kajitani, Lear Brace, Jose Humberto Trevino-Villarreal, Kaspar Trocha, Michael Robert MacArthur, Sarah Jayne Mitchell, James Robert Mitchell

Aging (Albany NY)· October 2021

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Plasma Hydrogen Sulfide Is Positively Associated With Post-operative Survival in Patients Undergoing Surgical Revascularization.
Alban Longchamp, Michael R MacArthur, Kaspar Trocha, Janine Ganahl, Charlotte G Mann, Sarah J Mitchell, James R Mitchell

Front Cardiovasc Med· October 2021

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Total protein, not amino acid composition, differs in plant-based versus omnivorous dietary patterns and determines metabolic health effects in mice.
Michael R MacArthur, Sarah J Mitchell, J Humberto Treviño-Villarreal, Yohann Grondin, Justin S Reynolds, James R Mitchell

Cell Metab· September 2021

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Gut Microbiota Predicts Healthy Late-Life Aging in Male Mice.
Shanlin Ke, Sarah J Mitchell, Michael R MacArthur, Alice E Kane, David A Sinclair, James R Mitchell

Nutrients· September 2021

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Down-Regulation of a Profibrotic Transforming Growth Factor-β1/Cellular Communication Network Factor 2/Matrix Metalloprotease 9 Axis by Triamcinolone Improves Idiopathic Subglottic Stenosis.
J Humberto Treviño-Villarreal, Justin S Reynolds, P Kent Langston, Andrew Thompson, James R Mitchell

Am J Pathol· August 2021

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The mTORC1-mediated activation of ATF4 promotes protein and glutathione synthesis downstream of growth signals.
Margaret E Torrence, Michael R MacArthur, Aaron M Hosios, Alexander J Valvezan, John M Asara, James R Mitchell

Elife· March 2021

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Adipose tissue parasite sequestration drives leptin production in mice and correlates with human cerebral malaria.
Pedro Mejia, J Humberto Treviño-Villarreal, Mariana De Niz, Elamaran Meibalan, Alban Longchamp, James R Mitchell

Sci Adv· March 2021

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Periprocedural Hydrogen Sulfide Therapy Improves Vascular Remodeling and Attenuates Vein Graft Disease.
Peter Kip, Ming Tao, Kaspar M Trocha, Michael R MacArthur, Hendrika A B Peters, Sarah J Mitchell, James R Mitchell

J Am Heart Assoc· November 2020

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Publisher Correction: Age and life expectancy clocks based on machine learning analysis of mouse frailty.
Michael B Schultz, Alice E Kane, Sarah J Mitchell, Michael R MacArthur, Elisa Warner, James R Mitchell

Nat Commun· October 2020

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