Publications by authors named "Jamie A Jarusiewicz"

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LCK-targeting molecular glues overcome resistance to inhibitor-based therapy in T-cell acute lymphoblastic leukemia.
Jun J Yang, Gisele Nishiguchi, Satoshi Yoshimura, Marisa Actis, Justin T Seffernick, Jamie A Jarusiewicz

bioRxiv· July 2025

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Development of an Orally Bioavailable LCK PROTAC Degrader as a Potential Therapeutic Approach to T-Cell Acute Lymphoblastic Leukemia.
Jamie A Jarusiewicz, Satoshi Yoshimura, Marisa Actis, Yong Li, Xiang Fu

J Med Chem· July 2024

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Chemical scaffold recycling: Structure-guided conversion of an HIV integrase inhibitor into a potent influenza virus RNA-dependent RNA polymerase inhibitor designed to minimize resistance potential.
Peter J Slavish, Maxime G Cuypers, Mary Ashley Rimmer, Alireza Abdolvahabi, Trushar Jeevan, Jamie A Jarusiewicz

Eur J Med Chem· February 2023

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Phenyl Dihydrouracil: An Alternative Cereblon Binder for PROTAC Design.
Jamie A Jarusiewicz, Satoshi Yoshimura, Anand Mayasundari, Marisa Actis, Anup Aggarwal

ACS Med Chem Lett· February 2023

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Development of Potent and Selective Janus Kinase 2/3 Directing PG-PROTACs.
Lisa J Alcock, Yunchao Chang, Jamie A Jarusiewicz, Marisa Actis, Stanley Nithianantham

ACS Med Chem Lett· March 2022

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Degradation of Janus kinases in CRLF2-rearranged acute lymphoblastic leukemia.
Yunchao Chang, Jaeki Min, Jamie A Jarusiewicz, Marisa Actis, Shanshan Yu-Chen Bradford

Blood· December 2021

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Identification of Potent, Selective, and Orally Bioavailable Small-Molecule GSPT1/2 Degraders from a Focused Library of Cereblon Modulators.
Gisele Nishiguchi, Fatemeh Keramatnia, Jaeki Min, Yunchao Chang, Barbara Jonchere, Jamie A Jarusiewicz

J Med Chem· June 2021

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Identification of Small Molecules Exhibiting Oxacillin Synergy through a Novel Assay for Inhibition of Expression in Methicillin-Resistant Staphylococcus aureus.
Hyun Lee, Susan Boyle-Vavra, Jinhong Ren, Jamie A Jarusiewicz, Lalit Kumar Sharma

Antimicrob Agents Chemother· September 2019

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Discovery of a Diaminopyrimidine FLT3 Inhibitor Active against Acute Myeloid Leukemia.
Jamie A Jarusiewicz, Jae Yoon Jeon, Michele C Connelly, Yizhe Chen, Lei Yang

ACS Omega· May 2017

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Inhibition of the function of class IIa HDACs by blocking their interaction with MEF2.
Nimanthi Jayathilaka, Aidong Han, Kevin J Gaffney, Raja Dey, Jamie A Jarusiewicz

Nucleic Acids Res· July 2012

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Thin layer chromatographic analysis of glucose and maltose in estivated Biomphalaria glabrata snails and those infected with Schistosoma mansoni.
Jamie A Jarusiewicz, Joseph Sherma, Bernard Fried

Comp Biochem Physiol B Biochem Mol Biol· February 2007

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Effects of diet on the carotenoid pigment and lipid content of Pomacea bridgesii as determined by quantitative high performance thin layer chromatography.
Jamie A Jarusiewicz, Bernard Fried, Joseph Sherma

Comp Biochem Physiol B Biochem Mol Biol· February 2006

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