Publications by authors named "Jamie Inshaw"

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Two randomised controlled phase 2 studies of the oral neutrophil elastase inhibitor alvelestat in alpha-1 antitrypsin deficiency.
J Michael Wells, Ingrid L Titlestad, Hanan Tanash, Alice M Turner, Kenneth R Chapman, Jamie Inshaw

Eur Respir J· December 2025

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Bayesian Effect Size Ranking to Prioritise Genetic Risk Variants in Common Diseases for Follow-Up Studies.
Daniel J M Crouch, Jamie R J Inshaw, Catherine C Robertson, Esther Ng, Jia-Yuan Zhang

Genet Epidemiol· January 2025

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Anti-inflammatory therapy with nebulized dornase alfa for severe COVID-19 pneumonia: a randomized unblinded trial.
Joanna C Porter, Jamie Inshaw, Vincente Joel Solis, Emma Denneny, Rebecca Evans

Elife· July 2024

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Phase 2 Dose-Finding Study in Patients with Gout Using SEL-212, a Novel PEGylated Uricase (SEL-037) Combined with Tolerogenic Nanoparticles (SEL-110).
Alan Kivitz, Wesley DeHaan, Rehan Azeem, Justin Park, Sheri Rhodes, Jamie Inshaw

Rheumatol Ther· August 2023

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Thymocyte regulatory variant alters transcription factor binding and protects from type 1 diabetes in infants.
Niina Sandholm, Arcadio Rubio García, Marcin L Pekalski, Jamie R J Inshaw, Antony J Cutler

Sci Rep· August 2022

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Circulating C-Peptide Levels in Living Children and Young People and Pancreatic β-Cell Loss in Pancreas Donors Across Type 1 Diabetes Disease Duration.
Alice L J Carr, Jamie R J Inshaw, Christine S Flaxman, Pia Leete, Rebecca C Wyatt

Diabetes· July 2022

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Childhood body size directly increases type 1 diabetes risk based on a lifecourse Mendelian randomization approach.
Tom G Richardson, Daniel J M Crouch, Grace M Power, Fernanda Morales-Berstein, Emma Hazelwood, Jamie R J Inshaw

Nat Commun· April 2022

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mutation alters immune system activation, inflammation, and risk of autoimmunity.
Carlo Sidore, Valeria Orrù, Eleonora Cocco, Maristella Steri, Jamie Rj Inshaw

Mult Scler· August 2021

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Fine-mapping, trans-ancestral and genomic analyses identify causal variants, cells, genes and drug targets for type 1 diabetes.
Catherine C Robertson, Jamie R J Inshaw, Suna Onengut-Gumuscu, Wei-Min Chen, David Flores Santa Cruz

Nat Genet· July 2021

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Analysis of overlapping genetic association in type 1 and type 2 diabetes.
Jamie R J Inshaw, Carlo Sidore, Francesco Cucca, M Irina Stefana, Daniel J M Crouch

Diabetologia· June 2021

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Correction: Comparison of methods for transcriptome imputation through application to two common complex diseases.
James J Fryett, Jamie Inshaw, Andrew P Morris, Heather J Cordell

Eur J Hum Genet· August 2020

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Author Correction: Approaches and advances in the genetic causes of autoimmune disease and their implications.
Jamie R J Inshaw, Antony J Cutler, Oliver S Burren, M Irina Stefana, John A Todd

Nat Immunol· June 2020

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A Global-Local Approach for Detecting Hotspots in Multiple-Response Regression.
Hélène Ruffieux, Anthony C Davison, Jörg Hager, Jamie Inshaw, Benjamin P Fairfax

Ann Appl Stat· June 2020

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Genetic Variants Predisposing Most Strongly to Type 1 Diabetes Diagnosed Under Age 7 Years Lie Near Candidate Genes That Function in the Immune System and in Pancreatic β-Cells.
Jamie R J Inshaw, Antony J Cutler, Daniel J M Crouch, Linda S Wicker, John A Todd

Diabetes Care· January 2020

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The impact of proinflammatory cytokines on the β-cell regulatory landscape provides insights into the genetics of type 1 diabetes.
Mireia Ramos-Rodríguez, Helena Raurell-Vila, Maikel L Colli, Maria Inês Alvelos, Marc Subirana-Granés, Jamie R J Inshaw

Nat Genet· November 2019

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Publisher Correction: Approaches and advances in the genetic causes of autoimmune disease and their implications.
Jamie R J Inshaw, Antony J Cutler, Oliver S Burren, M Irina Stefana, John A Todd

Nat Immunol· March 2019

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Virological remission after antiretroviral therapy interruption in female African HIV seroconverters.
Morgane Gossez, Genevieve Elizabeth Martin, Matthew Pace, Gita Ramjee, Anamika Premraj, Jamie Inshaw

AIDS· February 2019

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Comparison of methods for transcriptome imputation through application to two common complex diseases.
James J Fryett, Jamie Inshaw, Andrew P Morris, Heather J Cordell

Eur J Hum Genet· November 2018

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Approaches and advances in the genetic causes of autoimmune disease and their implications.
Jamie R J Inshaw, Antony J Cutler, Oliver S Burren, M Irina Stefana, John A Todd

Nat Immunol· July 2018

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The chromosome 6q22.33 region is associated with age at diagnosis of type 1 diabetes and disease risk in those diagnosed under 5 years of age.
Jamie R J Inshaw, Neil M Walker, Chris Wallace, Leonardo Bottolo, John A Todd

Diabetologia· January 2018

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Brief Report: Enhanced Normalization of CD4/CD8 Ratio With Earlier Antiretroviral Therapy at Primary HIV Infection.
John Thornhill, Jamie Inshaw, Pontiano Kaleebu, David Cooper, Gita Ramjee

J Acquir Immune Defic Syndr· September 2016

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BREATHER (PENTA 16) short-cycle therapy (SCT) (5 days on/2 days off) in young people with chronic human immunodeficiency virus infection: an open, randomised, parallel-group Phase II/III trial.
Karina Butler, Jamie Inshaw, Deborah Ford, Sarah Bernays, Karen Scott

Health Technol Assess· June 2016

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The Impact of HCV Infection Duration on HIV Disease Progression and Response to cART amongst HIV Seroconverters in the UK.
Jamie Inshaw, Clifford Leen, Martin Fisher, Richard Gilson, David Hawkins

PLoS One· May 2016

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Enhanced normalisation of CD4/CD8 ratio with early antiretroviral therapy in primary HIV infection.
John Thornhill, Jamie Inshaw, Soonita Oomeer, Pontiano Kaleebu, David Cooper

J Int AIDS Soc· January 2016

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Pharmacokinetics of pediatric lopinavir/ritonavir tablets in children when administered twice daily according to FDA weight bands.
Diane E T Bastiaans, Silvia Forcat, Hermione Lyall, Tim R Cressey, Rawiwan Hansudewechakul, Jamie R J Inshaw

Pediatr Infect Dis J· March 2014

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