Publications by authors named "Jan Beumer"

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Letrozole, abemaciclib and metformin in endometrial cancer: a non-randomized phase 2 trial.
Panagiotis A Konstantinopoulos, Ningxuan Zhou, Richard T Penson, Tien V Le, Susana Campos, Jan H Beumer

Nat Commun· December 2025

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Association of SULT2A1 Locus With Abiraterone Clearance in the Alliance A031201: Randomized Phase III Study of Enzalutamide Compared With Enzalutamide Plus Abiraterone for Metastatic Castration-Resistant Prostate Cancer.
Nadine Norton, Nicholas B Larson, Gregory D Jenkins, Jan H Beumer, Brooke Langevin

Clin Transl Sci· December 2025

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A phase 1 study of orally administered 5-fluoro-2'-deoxycytidine with tetrahydrouridine in patients with refractory solid tumors.
Alice P Chen, Shivaani Kummar, Larry Rubinstein, Jennifer Zlott, Geraldine O'Sullivan Coyne, Jan H Beumer

Cancer Chemother Pharmacol· December 2025

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The ATR Inhibitor Elimusertib in Combination with Cisplatin in Patients with Advanced Solid Tumors: A California Cancer Consortium Phase I Trial (NCI 10404).
Mamta Parikh, Nataliya V Uboha, Naoko Takebe, Kit Tam, Philippe L Bedard, Jan H Beumer

Cancer Res Commun· November 2025

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Clinical and translational study of ivosidenib plus nivolumab in advanced solid tumors harboring IDH1 mutations.
Matthew K Nguyen, Mark Jelinek, Arjun Singh, Brian Isett, Erica S Myers, Jan H Beumer

Oncologist· November 2025

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Phase 1 clinical trial of the ataxia telangiectasia and Rad3-related inhibitor berzosertib with irinotecan in patients with advanced solid tumors (ETCTN 9938).
Liza C Villaruz, Jingxiao Jin, Hong Wang, James J Lee, Jason J Luke, Jan H Beumer

Cancer· November 2025

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Phase Ib study of berzosertib, carboplatin, gemcitabine, and pembrolizumab in patients with squamous nonsmall lung cancer (ETCTN 10313).
Liza C Villaruz, Benjamin Schluger, Hong Wang, James Ohr, Daniel Petro, Jan H Beumer

Oncologist· November 2025

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Phase Ib study of enzalutamide with venetoclax in patients with metastatic castration-resistant prostate cancer.
Stuthi Perimbeti, Anmbreen Jamroze, Dharmesh Gopalakrishnan, Rohit Jain, Changchuan Jiang, Jan H Beumer

Cancer Chemother Pharmacol· November 2025

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Quantitation of Niraparib in Human Plasma by LC-MS/MS.
Tien V Le, Sarah E Taylor, Robert A Parise, Susan M Christner, Cortney Montgomery, Jan H Beumer

Biomed Chromatogr· September 2025

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Comparative in vivo toxicology of ATR inhibitors ceralasertib, elimusertib, and berzosertib alone and in combination with ionizing radiation.
Joshua J Deppas, Brian F Kiesel, Jianxia Guo, Lora H Rigatti, Joseph D Latoche, Jan H Beumer

Toxicol Appl Pharmacol· July 2025

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Quantitation of Tuvusertib (M1774) in Human Plasma by LC-MS/MS.
Tien V Le, Robert A Parise, Julianne L Holleran, Christopher J Bakkenist, Timothy Synold, Jan H Beumer

Biomed Chromatogr· July 2025

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Clinical and translational study of ivosidenib plus nivolumab in advanced solid tumors harboring IDH1 mutations.
Matthew K Nguyen, Mark Jelinek, Arjun Singh, Brian Isett, Erica S Myers, Jan Beumer

medRxiv· July 2025

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Phase 1 studies of the indenoisoquinolines LMP776 and LMP744 in patients with solid tumors and lymphomas.
Geraldine O'Sullivan Coyne, Shivaani Kummar, Larry V Rubinstein, Deborah Wilsker, Nancy Moore, Jan H Beumer

Cancer Chemother Pharmacol· May 2025

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Phase Ib Study of Enzalutamide with Venetoclax in Patients with Metastatic Castration-Resistant Prostate Cancer.
Stuthi Perimbeti, Anmbreen Jamroze, Dharmesh Gopalakrishnan, Rohit Jain, Changchuan Jiang, Jan H Beumer

medRxiv· April 2025

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A phase 1 study of the amino acid modulator pegcrisantaspase and venetoclax for relapsed or refractory acute myeloid leukemia.
Yuchen Liu, Dominique R Bollino, Osman M Bah, Erin T Strovel, Tien V Le, Jan H Beumer

Blood· January 2025

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Phase I trial of ATR inhibitor elimusertib with FOLFIRI in advanced or metastatic gastrointestinal malignancies (ETCTN 10406).
Anuradha Krishnamurthy, Hong Wang, John C Rhee, Diwakar Davar, Ryan H Moy, Jan H Beumer

Cancer Chemother Pharmacol· January 2025

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Quantitation of the DNA-dependent protein kinase inhibitor peposertib (M3814) and metabolite in human plasma by LC-MS/MS.
Susan M Christner, Robert A Parise, Christopher J Bakkenist, S Lindsey Davis, Ye Feng, Jan H Beumer

Biomed Chromatogr· December 2024

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Dose finding, bioavailability, and PK-PD of oral triapine with concurrent chemoradiation for locally advanced cervical cancer and vaginal cancer (ETCTN 9892).
Sarah E Taylor, Sarah Behr, Kristine L Cooper, Haider Mahdi, Denise Fabian, Jan H Beumer

Cancer Chemother Pharmacol· December 2024

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Exploring the Impact of the β-Catenin Mutations in Hepatocellular Carcinoma: An In-Depth Review.
Yassine Alami Idrissi, Mohammad Reza Rajabi, Jan H Beumer, Satdarshan P Monga, Anwaar Saeed

Cancer Control· October 2024

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Mitigation of Fetal Radiation Injury from Mid-Gestation Total-body Irradiation by Maternal Administration of Mitochondrial-Targeted GS-Nitroxide JP4-039.
Yijen L Wu, Anthony G Christodoulou, Jan H Beumer, Lora H Rigatti, Renee Fisher

Radiat Res· September 2024

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Non-linear IV pharmacokinetics of the ATR inhibitor berzosertib (M6620) in mice.
Joshua J Deppas, Brian F Kiesel, Jianxia Guo, Robert A Parise, D Andy Clump, Jan H Beumer

Cancer Chemother Pharmacol· August 2024

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Assessment of GFR in Patients with Cancer: A Statement from the American Society of Onco-Nephrology.
Abhijat Kitchlu, Verônica T Costa E Silva, Shuchi Anand, Jaya Kala, Ala Abudayyeh, Jan H Beumer

Clin J Am Soc Nephrol· August 2024

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Assessment of GFR in Patients with Cancer Part 2: Anticancer Therapies-Perspectives from the American Society of Onco-Nephrology (ASON).
Abhijat Kitchlu, Verônica T Costa E Silva, Shuchi Anand, Jaya Kala, Ala Abudayyeh, Jan H Beumer

Clin J Am Soc Nephrol· August 2024

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Quantitation of tazemetostat in human plasma using liquid chromatography-tandem mass spectrometry.
Marco Orleni, Robert A Parise, Julianne L Holleran, Jennifer E Amengual, Ye Feng, Jan H Beumer

Biomed Chromatogr· July 2024

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Deoxyuridine-rich cytoplasmic DNA antagonizes STING-dependent innate immune responses and sensitizes resistant tumors to anti-PD-L1 therapy.
Pinakin Pandya, Frank P Vendetti, Joseph El-Ghoubaira, Sudipta Pathak, Joshua J Deppas, Jan H Beumer

bioRxiv· April 2024

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