Publications by authors named "Jan Crowley"

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Astrocyte deletion of α2-Na/K ATPase triggers episodic motor paralysis in mice via a metabolic pathway.
Sarah E Smith, Xiaoying Chen, Lindsey M Brier, Jonathan R Bumstead, Nicholas R Rensing, Jan R Crowley

Nat Commun· December 2020

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Author Correction: High-protein diets increase cardiovascular risk by activating macrophage mTOR to suppress mitophagy.
Xiangyu Zhang, Ismail Sergin, Trent D Evans, Se-Jin Jeong, Astrid Rodriguez-Velez, Jan R Crowley

Nat Metab· September 2020

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Lactotrehalose, an Analog of Trehalose, Increases Energy Metabolism Without Promoting Clostridioides difficile Infection in Mice.
Yiming Zhang, Nurmohammad Shaikh, Jeremie L Ferey, Umesh D Wankhade, Sree V Chintapalli, Jan R Crowley

Gastroenterology· April 2020

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High-protein diets increase cardiovascular risk by activating macrophage mTOR to suppress mitophagy.
Xiangyu Zhang, Ismail Sergin, Trent D Evans, Se-Jin Jeong, Astrid Rodriguez-Velez, Jan R Crowley

Nat Metab· January 2020

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Metabolomic networks connect host-microbiome processes to human Clostridioides difficile infections.
John I Robinson, William H Weir, Jan R Crowley, Tiffany Hink, Kimberly A Reske

J Clin Invest· August 2019

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Extracellular pH Modulates Neuroendocrine Prostate Cancer Cell Metabolism and Susceptibility to the Mitochondrial Inhibitor Niclosamide.
Joseph E Ippolito, Matthew W Brandenburg, Xia Ge, Jan R Crowley, Kristopher M Kirmess

PLoS One· July 2017

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Exploiting macrophage autophagy-lysosomal biogenesis as a therapy for atherosclerosis.
Ismail Sergin, Trent D Evans, Xiangyu Zhang, Somashubhra Bhattacharya, Carl J Stokes, Jan R Crowley

Nat Commun· June 2017

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Human Metabolome-derived Cofactors Are Required for the Antibacterial Activity of Siderocalin in Urine.
Robin R Shields-Cutler, Jan R Crowley, Connelly D Miller, Ann E Stapleton, Weidong Cui

J Biol Chem· December 2016

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SLC2A8 (GLUT8) is a mammalian trehalose transporter required for trehalose-induced autophagy.
Allyson L Mayer, Cassandra B Higgins, Monique R Heitmeier, Thomas E Kraft, Xia Qian, Jan R Crowley

Sci Rep· December 2016

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Antivirulence C-Mannosides as Antibiotic-Sparing, Oral Therapeutics for Urinary Tract Infections.
Laurel Mydock-McGrane, Zachary Cusumano, Zhenfu Han, Jana Binkley, Maria Kostakioti, Jan Crowley

J Med Chem· October 2016

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Urinary Metabolomics Identifies a Molecular Correlate of Interstitial Cystitis/Bladder Pain Syndrome in a Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) Research Network Cohort.
Kaveri S Parker, Jan R Crowley, Alisa J Stephens-Shields, Adrie van Bokhoven, M Scott Lucia

EBioMedicine· May 2016

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Trehalose inhibits solute carrier 2A (SLC2A) proteins to induce autophagy and prevent hepatic steatosis.
Brian J DeBosch, Monique R Heitmeier, Allyson L Mayer, Cassandra B Higgins, Jan R Crowley

Sci Signal· February 2016

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The effect of dietary resistant starch type 2 on the microbiota and markers of gut inflammation in rural Malawi children.
M Isabel Ordiz, Thaddaeus D May, Kathie Mihindukulasuriya, John Martin, Jan Crowley

Microbiome· September 2015

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Deconvoluting heme biosynthesis to target blood-stage malaria parasites.
Paul A Sigala, Jan R Crowley, Jeffrey P Henderson, Daniel E Goldberg

Elife· July 2015

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Metal selectivity by the virulence-associated yersiniabactin metallophore system.
Eun-Ik Koh, Chia S Hung, Kaveri S Parker, Jan R Crowley, Daryl E Giblin

Metallomics· June 2015

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Human Urinary Composition Controls Antibacterial Activity of Siderocalin.
Robin R Shields-Cutler, Jan R Crowley, Chia S Hung, Ann E Stapleton, Courtney C Aldrich

J Biol Chem· June 2015

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Malaria parasites produce volatile mosquito attractants.
Megan Kelly, Chih-Ying Su, Chad Schaber, Jan R Crowley, Fong-Fu Hsu

mBio· March 2015

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The heme biosynthesis pathway is essential for Plasmodium falciparum development in mosquito stage but not in blood stages.
Hangjun Ke, Paul A Sigala, Kazutoyo Miura, Joanne M Morrisey, Michael W Mather, Jan R Crowley

J Biol Chem· December 2014

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A high-throughput fluorimetric assay for 2-hydroxyglutarate identifies Zaprinast as a glutaminase inhibitor.
Adnan Elhammali, Joseph E Ippolito, Lynne Collins, Jan Crowley, Jayne Marasa

Cancer Discov· July 2014

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Escherichia coli biofilms have an organized and complex extracellular matrix structure.
Chia Hung, Yizhou Zhou, Jerome S Pinkner, Karen W Dodson, Jan R Crowley

mBio· September 2013

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Substrate metabolism during basal and hyperinsulinemic conditions in adolescents and young-adults with Barth syndrome.
W Todd Cade, Carolyn T Spencer, Dominic N Reeds, Alan D Waggoner, Robert O'Connor, Jan R Crowley

J Inherit Metab Dis· January 2013

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Direct tests of enzymatic heme degradation by the malaria parasite Plasmodium falciparum.
Paul A Sigala, Jan R Crowley, Samantha Hsieh, Jeffrey P Henderson, Daniel E Goldberg

J Biol Chem· November 2012

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The siderophore yersiniabactin binds copper to protect pathogens during infection.
Kaveri S Chaturvedi, Chia S Hung, Jan R Crowley, Ann E Stapleton, Jeffrey P Henderson

Nat Chem Biol· August 2012

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Postprandial leucine and insulin responses and toxicological effects of a novel whey protein hydrolysate-based supplement in rats.
Ryan G Toedebusch, Thomas E Childs, Shari R Hamilton, Jan R Crowley, Frank W Booth

J Int Soc Sports Nutr· June 2012

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Lead optimization studies on FimH antagonists: discovery of potent and orally bioavailable ortho-substituted biphenyl mannosides.
Zhenfu Han, Jerome S Pinkner, Bradley Ford, Erik Chorell, Jan M Crowley

J Med Chem· April 2012

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