Publications by authors named "Jan Freijer"

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Oxycodone Effect on Pupil Constriction in Recreational Opioid Users: A Pharmacokinetic/Pharmacodynamic Meta-Analysis Approach.
Anna Dari, Stefan Buller, Michael Gautrois, Hans-Jürgen Stahlberg, Jens Rengelshausen, Jan Freijer

Clin Pharmacokinet· June 2021

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Population Pharmacokinetics of Tapentadol in Children from Birth to <18 Years Old.
Feras Khalil, Siak Leng Choi, Estelle Watson, Thomas M Tzschentke, Claudia Lefeber, Jan Freijer

J Pain Res· November 2020

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Population pharmacokinetic modeling to facilitate dose selection of tapentadol in the pediatric population.
Estelle Watson, Akash Khandelwal, Jan Freijer, John van den Anker, Claudia Lefeber

J Pain Res· October 2019

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Optimizing the glutamatergic challenge model for psychosis, using S+ -ketamine to induce psychomimetic symptoms in healthy volunteers.
Daniël Kleinloog, Anna Uit den Boogaard, Albert Dahan, René Mooren, Erica Klaassen, Jan Freijer

J Psychopharmacol· April 2015

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Population pharmacokinetic model of THC integrates oral, intravenous, and pulmonary dosing and characterizes short- and long-term pharmacokinetics.
Jules A A C Heuberger, Zheng Guan, Olubukayo-Opeyemi Oyetayo, Linda Klumpers, Paul D Morrison, Jan Freijer

Clin Pharmacokinet· February 2015

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Predicting the "First dose in children" of CYP3A-metabolized drugs: Evaluation of scaling approaches and insights into the CYP3A7-CYP3A4 switch at young ages.
Ashley Strougo, Ashraf Yassen, Claire Monnereau, Meindert Danhof, Jan Freijer

J Clin Pharmacol· September 2014

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Profiling the subjective effects of Δ⁹-tetrahydrocannabinol using visual analogue scales.
Daniël Kleinloog, Frits Roozen, Willem De Winter, Jan Freijer, Joop Van Gerven

Int J Methods Psychiatr Res· June 2014

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Monitoring prednisolone and prednisone in saliva: a population pharmacokinetic approach in healthy volunteers.
Nynke Teeninga, Zheng Guan, Jan Freijer, An F C Ruiter, Mariëtte T Ackermans

Ther Drug Monit· August 2013

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Novel Δ(9) -tetrahydrocannabinol formulation Namisol® has beneficial pharmacokinetics and promising pharmacodynamic effects.
Linda E Klumpers, Tim L Beumer, Johan G C van Hasselt, Astrid Lipplaa, Lennard B Karger, Jan I Freijer

Br J Clin Pharmacol· July 2012

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First dose in children: physiological insights into pharmacokinetic scaling approaches and their implications in paediatric drug development.
Ashley Strougo, Thomas Eissing, Ashraf Yassen, Stefan Willmann, Meindert Danhof, Jan Freijer

J Pharmacokinet Pharmacodyn· April 2012

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A semiphysiological population model for prediction of the pharmacokinetics of drugs under liver and renal disease conditions.
Ashley Strougo, Ashraf Yassen, Walter Krauwinkel, Meindert Danhof, Jan Freijer

Drug Metab Dispos· July 2011

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An example of optimal phase II design for exposure response modelling.
Alan Maloney, Marloes Schaddelee, Jan Freijer, Walter Krauwinkel, Marcel van Gelderen

J Pharmacokinet Pharmacodyn· October 2010

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Risk assessment in extrapolation of pharmacokinetics from preclinical data to humans.
Zvi Teitelbaum, Thierry Lave, Jan Freijer, Adam F Cohen

Clin Pharmacokinet· September 2010

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Pharmacokinetic/pharmacodynamic modelling of the EEG effects of opioids: the role of complex biophase distribution kinetics.
Dorien Groenendaal, Jan Freijer, Andrea Rosier, Dennis de Mik, Glynis Nicholls

Eur J Pharm Sci· July 2008

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Pharmacokinetic modeling of non-linear brain distribution of fluvoxamine in the rat.
Marian Geldof, Jan Freijer, Ludy van Beijsterveldt, Meindert Danhof

Pharm Res· April 2008

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Extensions to the visual predictive check to facilitate model performance evaluation.
Teun M Post, Jan I Freijer, Bart A Ploeger, Meindert Danhof

J Pharmacokinet Pharmacodyn· April 2008

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Mechanism-based pharmacodynamic modeling of S(-)-atenolol: estimation of in vivo affinity for the beta1-adrenoceptor with an agonist-antagonist interaction model.
Tamara J van Steeg, Jan Freijer, Meindert Danhof, Elizabeth C M de Lange

J Pharmacol Exp Ther· March 2008

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Mechanistic model for the acute effect of fluvoxamine on 5-HT and 5-HIAA concentrations in rat frontal cortex.
Marian Geldof, Jan I Freijer, Lambertus A Peletier, Ludy van Beijsterveldt, Meindert Danhof

Eur J Pharm Sci· March 2008

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Pharmacokinetic-pharmacodynamic modeling of the effect of fluvoxamine on p-chloroamphetamine-induced behavior.
Marian Geldof, Jan Freijer, Ludy van Beijsterveldt, Patrick C M Vermote, Anton A Megens

Eur J Pharm Sci· November 2007

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Application of the convection-dispersion equation to modelling oral drug absorption.
Jan I Freijer, Teun M Post, Bart A Ploeger, Joost DeJongh, Meindert Danhof

Bull Math Biol· January 2007

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Population pharmacokinetic model of fluvoxamine in rats: utility for application in animal behavioral studies.
Marian Geldof, Jan Freijer, Ludy van Beijsterveldt, Philip Timmerman, Abdellah Ahnaou

Eur J Pharm Sci· January 2007

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Disease system analysis: basic disease progression models in degenerative disease.
Teun M Post, Jan I Freijer, Joost DeJongh, Meindert Danhof

Pharm Res· July 2005

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Analysis of lobar differences in particle deposition in the human lung.
Ravi P Subramaniam, Bahman Asgharian, Jan I Freijer, Frederick J Miller, Satish Anjilvel

Inhal Toxicol· January 2003

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Risk assessment of deoxynivalenol in food: concentration limits, exposure and effects.
Moniek N Pieters, Jan Freijer, Bert-Jan Baars, Daniëlle C M Fiolet, Jacob van Klaveren

Adv Exp Med Biol· September 2002

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Particle size-dependent total mass deposition in lungs determines inhalation toxicity of cadmium chloride aerosols in rats. Application of a multiple path dosimetry model.
Flemming R Cassee, Hans Muijser, Evert Duistermaat, Jan J Freijer, Kees B Geerse

Arch Toxicol· June 2002

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