Publications by authors named "Jan Gruber"

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Reframing biological age as risk-equivalent age.
Sheng Fong, Woon-Puay Koh, Jan Gruber

Nat Aging· December 2025

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Open problems in ageing science: a roadmap for biogerontology.
Angelo Talay, Aleksey V Belikov, Paul Ka Po To, Hamid H Alfatemi, Uri Alon, Jan Gruber

Geroscience· November 2025

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Promorphinan and bisaporphine alkaloids from Alseodaphne peduncularis.
Sayed Mohammadhossein Modaresi, Premanand Krishnan, Wei-Meng Lim, Ling-Wei Hii, Kooi-Yeong Khaw, Jan Gruber

Fitoterapia· September 2025

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DoliClock: a lipid-based aging clock reveals accelerated aging in neurological disorders.
Djakim Latumalea, Maximilian Unfried, Diogo Barardo, Jan Gruber, Brian K Kennedy

Aging (Albany NY)· June 2025

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LinAge2: providing actionable insights and benchmarking with epigenetic clocks.
Sheng Fong, Kirill A Denisov, Anastasiia A Nefedova, Brian K Kennedy, Jan Gruber

NPJ Aging· April 2025

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The impact of short-lived controls on the interpretation of lifespan experiments and progress in geroscience - Through the lens of the "900-day rule".
Kamil Pabis, Diogo Barardo, Jan Gruber, Olga Sirbu, Marco Malavolta

Ageing Res Rev· November 2024

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Principal component-based clinical aging clocks identify signatures of healthy aging and targets for clinical intervention.
Sheng Fong, Kamil Pabis, Djakim Latumalea, Nomuundari Dugersuren, Maximilian Unfried, Jan Gruber

Nat Aging· August 2024

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Evaluating the inter-species transmission risk of amyloid beta peptide aggregates via ingestion.
Joshua Raine, Nicholas Tolwinski, Jan Gruber, Ajay S Mathuru

Alzheimers Res Ther· June 2024

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Towards Healthy Longevity: Comprehensive Insights from Molecular Targets and Biomarkers to Biological Clocks.
Khalishah Yusri, Sanjay Kumar, Sheng Fong, Jan Gruber, Vincenzo Sorrentino

Int J Mol Sci· June 2024

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A concerted increase in readthrough and intron retention drives transposon expression during aging and senescence.
Kamil Pabis, Diogo Barardo, Olga Sirbu, Kumar Selvarajoo, Jan Gruber

Elife· April 2024

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Efficiency of Protein Renewal Is Limited by Feed Intake and Not by Protein Lifetime in Aging .
Jasmeet Kaur Khanijou, Zhuangli Yee, Manfred Raida, Jin Meng Lee, Evan Zhi En Tay, Jan Gruber

J Proteome Res· November 2022

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Combining stem cell rejuvenation and senescence targeting to synergistically extend lifespan.
Prameet Kaur, Agimaa Otgonbaatar, Anupriya Ramamoorthy, Ellora Hui Zhen Chua, Nathan Harmston, Jan Gruber

Aging (Albany NY)· October 2022

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Glutathione catabolism by Enterobacteriaceae species to hydrogen sulphide adversely affects the viability of host systems in the presence of 5'fluorodeoxyuridine.
Daniel Rui Xiang Lim, Yahua Chen, Li Fang Ng, Jan Gruber, Yunn-Hwen Gan

Mol Microbiol· May 2022

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LipidClock: A Lipid-Based Predictor of Biological Age.
Maximilian Unfried, Li Fang Ng, Amaury Cazenave-Gassiot, Krishna Chaithanya Batchu, Brian K Kennedy, Jan Gruber

Front Aging· May 2022

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A small-molecule Psora-4 acts as a caloric restriction mimetic to promote longevity in C. elegans.
Tesfahun Dessale Admasu, Diogo Barardo, Li Fang Ng, Krishna Chaithanya Batchu, Amaury Cazenave-Gassiot, Jan Gruber

Geroscience· April 2022

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Thermodynamic analysis of DNA hybridization signatures near mitochondrial DNA deletion breakpoints.
Lakshmi Narayanan Lakshmanan, Zhuangli Yee, Barry Halliwell, Jan Gruber, Rudiyanto Gunawan

iScience· March 2021

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Inhibition of mTOR decreases insoluble proteins burden by reducing translation in C. elegans.
Zhuangli Yee, Shaun Hsien Yang Lim, Li Fang Ng, Jan Gruber

Biogerontology· February 2021

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Use of Optogenetic Amyloid-β to Monitor Protein Aggregation in and .
Prameet Kaur, Caroline Kibat, Emelyne Teo, Jan Gruber, Ajay Mathuru

Bio Protoc· December 2020

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Drug synergy as a strategy for compression of morbidity in a Caenorhabditis elegans model of Alzheimer's disease.
Emelyne Teo, Sheng Fong, Nicholas Tolwinski, Jan Gruber

Geroscience· June 2020

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Lifespan and healthspan benefits of exogenous HS in are independent from effects downstream of mutation.
Li Theng Ng, Li Fang Ng, Richard Ming Yi Tang, Diogo Barardo, Barry Halliwell, Jan Gruber

NPJ Aging Mech Dis· June 2020

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Application of optogenetic Amyloid-β distinguishes between metabolic and physical damages in neurodegeneration.
Chu Hsien Lim, Prameet Kaur, Emelyne Teo, Vanessa Yuk Man Lam, Fangchen Zhu, Jan Gruber

Elife· March 2020

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Metabolic stress is a primary pathogenic event in transgenic expressing pan-neuronal human amyloid beta.
Emelyne Teo, Sudharshan Ravi, Diogo Barardo, Hyung-Seok Kim, Sheng Fong, Jan Gruber

Elife· October 2019

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Inhibition of amyloid-induced toxicity by ergothioneine in a transgenic Caenorhabditis elegans model.
Irwin K Cheah, Li-Theng Ng, Li-Fang Ng, Vanessa Y Lam, Jan Gruber

FEBS Lett· August 2019

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WNT Signaling in Disease.
Li Fang Ng, Prameet Kaur, Nawat Bunnag, Jahnavi Suresh, Isabelle Chiao Han Sung, Jan Gruber

Cells· August 2019

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Measurement of Respiration Rate in Live .
Li Fang Ng, Jan Gruber

Bio Protoc· May 2019

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