Publications by authors named "Jan Hilpert"

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Polycystic ovary syndrome and elevated body mass index independently increase type 2 diabetes risk with obesity-mediated risk dominating: a real-world data analysis of US patients.
Konstantin Sharafutdinov, Jan Hilpert, Rolf Burghaus, Christian Diedrich, Jörg Lippert

Fertil Steril· September 2025

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Risk Factors for Incident Polycystic Ovary Syndrome Diagnosis.
Jacob P Christ, Onchee Yu, Brooke Barton, Renate Schulze-Rath, Jane Grafton, Jan Hilpert

J Womens Health (Larchmt)· July 2024

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Hepatotoxicity of AKR1C3 Inhibitor BAY1128688: Findings from an Early Terminated Phase IIa Trial for the Treatment of Endometriosis.
Jan Hilpert, Esther Groettrup-Wolfers, Hristiyan Kosturski, Laura Bennett, Catriona L K Barnes

Drugs R D· September 2023

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Incidence, prevalence, and trends in polycystic ovary syndrome diagnosis: a United States population-based study from 2006 to 2019.
Onchee Yu, Jacob P Christ, Renate Schulze-Rath, Jennifer Covey, Ann Kelley, Jan Hilpert

Am J Obstet Gynecol· July 2023

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Novel aldo-keto reductase 1C3 inhibitor affects androgen metabolism but not ovarian function in healthy women: a phase 1 study.
Isabella Gashaw, Stefanie Reif, Herbert Wiesinger, Andreas Kaiser, Frank S Zollmann, Jan Hilpert

Eur J Endocrinol· July 2023

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Science-Based Approach to Harmonize Contraception Recommendations in Clinical Trials and Pharmaceutical Labels.
Christopher J Bowman, Nathalie Becourt-Lhote, Virginie Boulifard, Rüdiger Cordts, Solange Corriol-Rohou, Jan Hilpert

Clin Pharmacol Ther· February 2023

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First administration of the Fc-attenuated anti-β amyloid antibody GSK933776 to patients with mild Alzheimer's disease: a randomized, placebo-controlled study.
Niels Andreasen, Monica Simeoni, Henrik Ostlund, Pia I Lisjo, Tormod Fladby, Jan Hilpert

PLoS One· February 2016

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An adaptive design to investigate the effect of ketoconazole on pharmacokinetics of GSK239512 in healthy male volunteers.
Jianfeng Xu, Jan Hilpert, Kai Wu, Benjamin van Hecke, Gary Collins

J Clin Pharmacol· May 2015

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Modulation of β-amyloid by a single dose of GSK933776 in patients with mild Alzheimer's disease: a phase I study.
Thomas Leyhe, Niels Andreasen, Monica Simeoni, Arno Reich, Christine Af von Arnim, Jan Hilpert

Alzheimers Res Ther· August 2014

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Systemic administration of Abeta mAb reduces retinal deposition of Abeta and activated complement C3 in age-related macular degeneration mouse model.
Ian Catchpole, Volker Germaschewski, Jaimie Hoh Kam, Peter Lundh von Leithner, Susannah Ford, Jan Hilpert

PLoS One· January 2014

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Biological response genes after single dose administration of interferon beta-1b to healthy male volunteers.
Jan Hilpert, Johanna M Beekman, Susanne Schwenke, Kristin Kowal, David Bauer

J Neuroimmunol· August 2008

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VTE Risk assessment - a prognostic Model: BATER Cohort Study of young women.
Lothar Aj Heinemann, Thai Dominh, Anita Assmann, Wolfgang Schramm, Rolf Schürmann, Jan Hilpert

Thromb J· April 2005

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Bradykinin-induced pulmonary vasoconstriction is time and inducible nitric oxide synthase dependent in a peritonitis sepsis model.
Lars G Fischer, Jan H Hilpert, Hendrik Freise, Doreen Wendholt, Hugo Van Aken

Anesth Analg· September 2004

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Low-density lipoprotein receptor-related protein interacts with MafB, a regulator of hindbrain development.
Helle Heibroch Petersen, Jan Hilpert, Christian Jacobsen, Annick Lauwers, Anton J M Roebroek

FEBS Lett· May 2004

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Functional interaction of megalin with the megalinbinding protein (MegBP), a novel tetratrico peptide repeat-containing adaptor molecule.
Helle Heibroch Petersen, Jan Hilpert, Daniel Militz, Valerie Zandler, Christian Jacobsen

J Cell Sci· February 2003

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Expression profiling confirms the role of endocytic receptor megalin in renal vitamin D3 metabolism.
Jan Hilpert, Lise Wogensen, Thomas Thykjaer, Maren Wellner, Uwe Schlichting

Kidney Int· November 2002

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Megalin deficiency offers protection from renal aminoglycoside accumulation.
Christian Schmitz, Jan Hilpert, Christian Jacobsen, Christian Boensch, Erik Ilsø Christensen

J Biol Chem· January 2002

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