Publications by authors named "Jan Homann"

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Redefining ALS: Large-scale proteomic profiling reveals a prolonged pre-diagnostic phase with immune, muscular, metabolic, and brain involvement.
Jan Homann, Roxanna Korologou-Linden, Vivian Viallon, Sarah Morgan, Valerija Dobricic

Res Sq· September 2025

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DunedinPACE predicts incident metabolic syndrome: cross-sectional and longitudinal data from the Berlin Aging Study II.
Ilja Demuth, Valentin Max Vetter, Jan Homann, Marit Philine Junge, Vera Regitz-Zagrosek

J Gerontol A Biol Sci Med Sci· August 2025

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Redefining ALS: Large-scale proteomic profiling reveals a prolonged pre-diagnostic phase with immune, muscular, metabolic, and brain involvement.
Jan Homann, Roxanna Korologou-Linden, Vivian Viallon, Sarah Morgan, Valerija Dobricic

medRxiv· August 2025

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Associations of proteomic age with mortality and incident chronic diseases in the European Prospective Investigation into Cancer and Nutrition (EPIC).
Oliver Robinson, Han Xiao, Jan Homann, Vivian Viallon, Pietro Ferrari

Res Sq· July 2025

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Large-scale plasma proteomics uncovers preclinical molecular signatures of Parkinson's disease and overlap with other neurodegenerative disorders.
Jan Homann, Alexander G Smith, Sarah Morgan, Elisabet A Frick, Fangyu Liu

medRxiv· July 2025

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Cross-sectional and Longitudinal Relationship Between Sex Hormones and 6 Epigenetic Clocks in Older Adults: Results of the Berlin Aging Study II.
Hannah Schmid, Valentin Max Vetter, Jan Homann, Vivien Bahr, Christina M Lill

J Gerontol A Biol Sci Med Sci· June 2025

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There Are Multiple Clocks That Time Us: Cross-Sectional and Longitudinal Associations Among 14 Alternative Indicators of Age and Aging.
Johanna Drewelies, Jan Homann, Valentin Max Vetter, Sandra Düzel, Simone Kühn

J Gerontol A Biol Sci Med Sci· May 2025

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(Dys)regulation of the Immune System in Parkinson's Disease: Methodologies, Techniques, and Key Findings from Human Studies.
Christina M Lill, Alessia di Flora, Leonardo A Sechi, Frederico C Pereira, Nicoleta Moisoi, Jan Homann

Aging Dis· May 2025

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Lifestyle, Early-life, and Genetic Health Risk Factors Underlying the Brain Age Gap: A Mega-Analysis Across 3,934 Individuals from the ENIGMA MDD Consortium.
Laura K M Han, Yara J Toenders, Xueyi Shen, Yuri Milaneschi, Heather C Whalley, Jan Homann

bioRxiv· May 2025

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Low blood levels of selenium, selenoprotein P and GPx3 are associated with accelerated biological aging: results from the Berlin Aging Study II (BASE-II).
Valentin Max Vetter, Kamil Demircan, Jan Homann, Thilo Samson Chillon, Michael Mülleder

Clin Epigenetics· April 2025

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Peripheral Immune Profiles in Individuals at Genetic Risk of Amyotrophic Lateral Sclerosis and Alzheimer's Disease.
Laura Deecke, Olena Ohlei, David Goldeck, Jan Homann, Sarah Toepfer

Cells· February 2025

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Immune Cell Distributions in the Blood of Healthy Individuals at High Genetic Risk of Parkinson's Disease.
Laura Deecke, David Goldeck, Olena Ohlei, Jan Homann, Ilja Demuth

Int J Mol Sci· December 2024

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Associations of milk, dairy products, calcium and vitamin D intake with risk of developing Parkinson´s disease within the EPIC4ND cohort.
Mareike Gröninger, Jara Sabin, Rudolf Kaaks, Pilar Amiano, Dagfinn Aune, Jan Homann

Eur J Epidemiol· November 2024

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Blood-based multivariate methylation risk score for cognitive impairment and dementia.
Jarno Koetsier, Rachel Cavill, Rick Reijnders, Joshua Harvey, Jan Homann

Alzheimers Dement· October 2024

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Variants in the TERT Gene Increase the Occurrence of Solar Lentigines by Modifying Telomerase Expression Exclusively in the Skin.
Laura Deecke, Olena Ohlei, Jan Homann, Jessica Stagge, Valerija Dobricic

J Invest Dermatol· June 2024

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No increase of CD8+ TEMRA cells in the blood of healthy adults at high genetic risk of Alzheimer's disease.
Laura Deecke, Jan Homann, David Goldeck, Olena Ohlei, Valerija Dobricic

Alzheimers Dement· April 2024

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Change in body weight of older adults before and during the COVID-19 pandemic: longitudinal results from the Berlin Aging Study II.
Valentin Max Vetter, Johanna Drewelies, Sandra Düzel, Jan Homann, Lil Meyer-Arndt

J Nutr Health Aging· April 2024

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Genome-wide QTL mapping across three tissues highlights several Alzheimer's and Parkinson's disease loci potentially acting via DNA methylation.
Olena Ohlei, Yasmine Sommerer, Valerija Dobricic, Jan Homann, Laura Deecke

medRxiv· December 2023

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Multiomics profiling of human plasma and cerebrospinal fluid reveals ATN-derived networks and highlights causal links in Alzheimer's disease.
Liu Shi, Jin Xu, Rebecca Green, Asger Wretlind, Jan Homann

Alzheimers Dement· August 2023

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Genome-Wide Association Study of Alzheimer's Disease Brain Imaging Biomarkers and Neuropsychological Phenotypes in the European Medical Information Framework for Alzheimer's Disease Multimodal Biomarker Discovery Dataset.
Jan Homann, Tim Osburg, Olena Ohlei, Valerija Dobricic, Laura Deecke

Front Aging Neurosci· March 2022

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Novel stimuli evoke excess activity in the mouse primary visual cortex.
Jan Homann, Sue Ann Koay, Kevin S Chen, David W Tank, Michael J Berry

Proc Natl Acad Sci U S A· February 2022

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A Mammalian Retinal Ganglion Cell Implements a Neuronal Computation That Maximizes the SNR of Its Postsynaptic Currents.
Jan Homann, Michael A Freed

J Neurosci· February 2017

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Transformation of stimulus correlations by the retina.
Kristina D Simmons, Jason S Prentice, Gašper Tkačik, Jan Homann, Heather K Yee

PLoS Comput Biol· August 2014

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Fast, scalable, Bayesian spike identification for multi-electrode arrays.
Jason S Prentice, Jan Homann, Kristina D Simmons, Gašper Tkačik, Vijay Balasubramanian

PLoS One· December 2011

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