Publications by authors named "Jan Ko"

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Identification of distinct conformations associated with monomers and fibril assemblies of mutant huntingtin.
Jan Ko, J Mario Isas, Adam Sabbaugh, Jung Hyun Yoo, Nitin K Pandey

Hum Mol Genet· July 2018

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IKKβ and mutant huntingtin interactions regulate the expression of IL-34: implications for microglial-mediated neurodegeneration in HD.
Ali Khoshnan, Adam Sabbaugh, Barbara Calamini, Steven A Marinero, Denise E Dunn, Jan Ko

Hum Mol Genet· November 2017

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Antibodies and intrabodies against huntingtin: production and screening of monoclonals and single-chain recombinant forms.
Ali Khoshnan, Susan Ou, Jan Ko, Paul H Patterson

Methods Mol Biol· January 2014

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Intrabody gene therapy ameliorates motor, cognitive, and neuropathological symptoms in multiple mouse models of Huntington's disease.
Amber L Southwell, Jan Ko, Paul H Patterson

J Neurosci· October 2009

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Monoclonal antibodies recognize distinct conformational epitopes formed by polyglutamine in a mutant huntingtin fragment.
Justin Legleiter, Gregor P Lotz, Jason Miller, Jan Ko, Cheping Ng

J Biol Chem· August 2009

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Structures of Abeta-related peptide--monoclonal antibody complexes.
Anna Gardberg, Lezlee Dice, Kathleen Pridgen, Jan Ko, Paul Patterson

Biochemistry· June 2009

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IKKalpha and IKKbeta regulation of DNA damage-induced cleavage of huntingtin.
Ali Khoshnan, Jan Ko, Simona Tescu, Patrick Brundin, Paul H Patterson

PLoS One· June 2009

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Molecular basis for passive immunotherapy of Alzheimer's disease.
Anna S Gardberg, Lezlee T Dice, Susan Ou, Rebecca L Rich, Elizabeth Helmbrecht, Jan Ko

Proc Natl Acad Sci U S A· October 2007

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Antibodies against huntingtin: production and screening of monoclonals and single-chain recombinant forms.
Ali Khoshnan, Susan Ou, Jan Ko, Paul H Patterson

Methods Mol Biol· September 2004

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Activation of the IkappaB kinase complex and nuclear factor-kappaB contributes to mutant huntingtin neurotoxicity.
Ali Khoshnan, Jan Ko, Erin E Watkin, Lisa A Paige, Peter H Reinhart

J Neurosci· September 2004

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Neonatal impact of leukemia inhibitory factor on neurobehavioral development in rats.
Yuichiro Watanabe, Shinya Hashimoto, Akiyoshi Kakita, Hitoshi Takahashi, Jan Ko, Makoto Mizuno

Neurosci Res· March 2004

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Effects of intracellular expression of anti-huntingtin antibodies of various specificities on mutant huntingtin aggregation and toxicity.
Ali Khoshnan, Jan Ko, Paul H Patterson

Proc Natl Acad Sci U S A· January 2002

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