Publications by authors named "Jan Koval"

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The First In Vivo Study Shows That Gyrophoric Acid Changes Behavior of Healthy Laboratory Rats.
Patrik Simko, Andrea Leskanicova, Maria Suvakova-Nunhart, Jan Koval, Nela Zidekova

Int J Mol Sci· June 2024

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In vitro investigating of anticancer activity of new 7-MEOTA-tacrine heterodimers.
Jana Janockova, Jan Korabecny, Jana Plsikova, Katerina Babkova, Eva Konkolova, Jan Koval

J Enzyme Inhib Med Chem· December 2019

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Histone deacetylase inhibitors potentiate photodynamic therapy in colon cancer cells marked by chromatin-mediated epigenetic regulation of .
Andrea Halaburková, Rastislav Jendželovský, Ján Kovaľ, Zdenko Herceg, Peter Fedoročko

Clin Epigenetics· April 2018

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Proadifen sensitizes resistant ovarian adenocarcinoma cells to cisplatin.
Rastislav Jendželovský, Zuzana Jendželovská, Lucia Hiľovská, Ján Kovaľ, Jaromír Mikeš

Toxicol Lett· January 2016

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Downregulation of BCRP and anti-apoptotic proteins by proadifen (SKF-525A) is responsible for the enhanced mitoxantrone accumulation and toxicity in mitoxantrone-resistant human promyelocytic leukemia cells.
Lucia Hiľovská, Rastislav Jendželovský, Zuzana Jendželovská, Ján Kovaľ, Peter Fedoročko

Int J Oncol· October 2015

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Potentiation of hypericin-mediated photodynamic therapy cytotoxicity by MK-886: focus on ABC transporters, GDF-15 and redox status.
Barbora Kuchárová, Jaromír Mikeš, Rastislav Jendželovský, Jana Vargová, Lucia Mikešová

Photodiagnosis Photodyn Ther· September 2015

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Inhibition of DNA topoisomerases I and II and growth inhibition of HL-60 cells by novel acridine-based compounds.
Jana Janočková, Jana Plšíková, Jana Kašpárková, Viktor Brabec, Rastislav Jendželovský

Eur J Pharm Sci· August 2015

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Tacrine derivatives as dual topoisomerase I and II catalytic inhibitors.
Jana Janočková, Jana Plšíková, Ján Koval', Rastislav Jendželovský, Jaromír Mikeš

Bioorg Chem· April 2015

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Novel trisubstituted acridines as human telomeric quadruplex binding ligands.
Jan Ungvarsky, Jana Plsikova, Ladislav Janovec, Jan Koval, Jaromir Mikes

Bioorg Chem· December 2014

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Single pre-treatment with hypericin, a St. John's wort secondary metabolite, attenuates cisplatin- and mitoxantrone-induced cell death in A2780, A2780cis and HL-60 cells.
Zuzana Jendželovská, Rastislav Jendželovský, Lucia Hiľovská, Ján Kovaľ, Jaromír Mikeš

Toxicol In Vitro· October 2014

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Conjunction of glutathione level, NAD(P)H/FAD redox status and hypericin content as a potential factor affecting colon cancer cell resistance to photodynamic therapy with hypericin.
Lucia Mikešová, Jaromír Mikeš, Ján Kovaľ, Katarína Gyurászová, L'ubomír Culka

Photodiagnosis Photodyn Ther· December 2013

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Procedure for improved cleaning of FACSAria cuvette flow cell.
Jaromír Mikeš, Ján Kovaĺ, Rastislav Jendželovský, Lucia Mikešová, Zuzana Sinkorová

Cytometry A· June 2013

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3,6-bis(3-alkylguanidino)acridines as DNA-intercalating antitumor agents.
Jana Plsikova, Ladislav Janovec, Jan Koval, Jan Ungvarsky, Jaromir Mikes

Eur J Med Chem· November 2012

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Inhibition of GSK-3β reverses the pro-apoptotic effect of proadifen (SKF-525A) in HT-29 colon adenocarcinoma cells.
Rastislav Jendželovský, Ján Koval, Jaromír Mikeš, Zuzana Papčová, Jana Plšíková

Toxicol In Vitro· September 2012

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Lower sensitivity of FHC fetal colon epithelial cells to photodynamic therapy compared to HT-29 colon adenocarcinoma cells despite higher intracellular accumulation of hypericin.
Jaromír Mikeš, Martina Hýžďalová, Lenka Kočí, Rastislav Jendželovský, Ján Kovaľ

Photochem Photobiol Sci· April 2011

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Novel observations on the origin of ependymal cells in the ventricular zone of the rat spinal cord.
Juraj Sevc, Zuzana Daxnerová, Viera Haňová, Ján Koval'

Acta Histochem· February 2011

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Photoactivated hypericin induces downregulation of HER2 gene expression.
Peter Solár, Peter Ferenc, Ján Koval', Jaromír Mikeš, Zuzana Solárová

Radiat Res· January 2011

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PUFAs enhance oxidative stress and apoptosis in tumour cells exposed to hypericin-mediated PDT.
Martin Kello, Jaromír Mikes, Rastislav Jendzelovský, Ján Koval, Peter Fedorocko

Photochem Photobiol Sci· September 2010

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Degradation of HER2 receptor through hypericin-mediated photodynamic therapy.
Ján Koval, Jaromír Mikes, Rastislav Jendzelovský, Martin Kello, Peter Solár

Photochem Photobiol· August 2010

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Drug efflux transporters, MRP1 and BCRP, affect the outcome of hypericin-mediated photodynamic therapy in HT-29 adenocarcinoma cells.
Rastislav Jendzelovský, Jaromír Mikes, Ján Koval', Karel Soucek, Jirina Procházková

Photochem Photobiol Sci· December 2009

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The role of p53 in the efficiency of photodynamic therapy with hypericin and subsequent long-term survival of colon cancer cells.
Jaromír Mikes, Ján Koval', Rastislav Jendzelovský, Veronika Sacková, Ivana Uhrinová

Photochem Photobiol Sci· November 2009

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Erythropoietin inhibits apoptosis induced by photodynamic therapy in ovarian cancer cells.
Peter Solár, Ján Koval, Jaromír Mikes, Ján Kleban, Zuzana Solárová

Mol Cancer Ther· August 2008

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Cytotoxic activity of proflavine diureas: synthesis, antitumor, evaluation and DNA binding properties of 1',1''-(acridin-3,6-diyl)-3',3''-dialkyldiureas.
Mária Kozurková, Danica Sabolová, Ladislav Janovec, Jaromír Mikes, Ján Koval'

Bioorg Med Chem· April 2008

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Modulation of hypericin photodynamic therapy by pretreatment with 12 various inhibitors of arachidonic acid metabolism in colon adenocarcinoma HT-29 cells.
Ján Kleban, Jaromír Mikes, Beáta Szilárdiová, Ján Koval, Veronika Sacková

Photochem Photobiol· January 2008

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