Publications by authors named "Jan Mathony"

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Engineering the Link: From Genome Interaction Maps to Functional Insight.
Frido Petersen, Simon Westermann, Valeriia Smialkovska, Jan Mathony, Angelika Feldmann

Adv Biol (Weinh)· December 2025

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Rational engineering of allosteric protein switches by in silico prediction of domain insertion sites.
Benedict Wolf, Pegi Shehu, Luca Brenker, Anna-Lisa von Bachmann, Ann-Sophie Kroell, Jan Mathony

Nat Methods· August 2025

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A versatile anti-CRISPR platform for opto- and chemogenetic control of CRISPR-Cas9 and Cas12 across a wide range of orthologs.
Luca Brenker, Sabine Aschenbrenner, Felix Bubeck, Kaloyan Staykov, Carolin Gebhardt, Jan Mathony

Nucleic Acids Res· July 2025

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A modular toolbox for the optogenetic deactivation of transcription.
Philipp Muench, Matteo Fiumara, Nicholas Southern, Davide Coda, Sabine Aschenbrenner, Jan Mathony

Nucleic Acids Res· January 2025

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A deep mutational scanning platform to characterize the fitness landscape of anti-CRISPR proteins.
Tobias Stadelmann, Daniel Heid, Michael Jendrusch, Jan Mathony, Sabine Aschenbrenner

Nucleic Acids Res· December 2024

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Dissecting the Determinants of Domain Insertion Tolerance and Allostery in Proteins.
Jan Mathony, Sabine Aschenbrenner, Philipp Becker, Dominik Niopek

Adv Sci (Weinh)· October 2023

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Transcriptomics-inferred dynamics of SARS-CoV-2 interactions with host epithelial cells.
Lukas Adam, Megan Stanifer, Fabian Springer, Jan Mathony, Maik Brune

Sci Signal· September 2023

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Enlightening Allostery: Designing Switchable Proteins by Photoreceptor Fusion.
Jan Mathony, Dominik Niopek

Adv Biol (Weinh)· May 2021

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Optogenetics and CRISPR: A New Relationship Built to Last.
Jan Mathony, Mareike D Hoffmann, Dominik Niopek

Methods Mol Biol· March 2021

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Optogenetic control of Neisseria meningitidis Cas9 genome editing using an engineered, light-switchable anti-CRISPR protein.
Mareike D Hoffmann, Jan Mathony, Julius Upmeier Zu Belzen, Zander Harteveld, Sabine Aschenbrenner

Nucleic Acids Res· March 2021

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Computational design of anti-CRISPR proteins with improved inhibition potency.
Jan Mathony, Zander Harteveld, Carolin Schmelas, Julius Upmeier Zu Belzen, Sabine Aschenbrenner

Nat Chem Biol· July 2020

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