Publications by authors named "Jan Misik"

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Tacrine and its 7-methoxy derivate; time-change concentration in plasma and brain tissue and basic toxicological profile in rats.
Jana Zdarova Karasova, Ondrej Soukup, Jan Korabecny, Milos Hroch, Marketa Krejciova, Jan Misik

Drug Chem Toxicol· March 2021

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Simple validated method of LC-MS/MS determination of BZ agent in rat plasma samples.
David Herman, Alzbeta Dlabkova, Lenka Cechova, Nela Vanova, Jan Misik

Drug Test Anal· April 2020

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Pharmacological and toxicological in vitro and in vivo effect of higher doses of oxime reactivators.
Vendula Hepnarova, Lubica Muckova, Avi Ring, Jaroslav Pejchal, David Herman, Jan Misik

Toxicol Appl Pharmacol· November 2019

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The Concentration of Memantine in the Cerebrospinal Fluid of Alzheimer's Disease Patients and Its Consequence to Oxidative Stress Biomarkers.
Martin Valis, David Herman, Nela Vanova, Jiri Masopust, Oldrich Vysata, Jan Misik

Front Pharmacol· August 2019

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Cholinesterase Inhibitor 6-Chlorotacrine - In Vivo Toxicological Profile and Behavioural Effects.
Jan Misik, Eugenie Nepovimova, Jaroslav Pejchal, Jiri Kassa, Jan Korabecny

Curr Alzheimer Res· May 2019

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Orexin supplementation in narcolepsy treatment: A review.
Eugenie Nepovimova, Jana Janockova, Jan Misik, Stepan Kubik, Ales Stuchlik

Med Res Rev· May 2019

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Novel tacrine-tryptophan hybrids: Multi-target directed ligands as potential treatment for Alzheimer's disease.
Katarina Chalupova, Jan Korabecny, Manuela Bartolini, Barbara Monti, Doriano Lamba, Jan Misik

Eur J Med Chem· April 2019

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The benefit of combinations of oximes for the ability of antidotal treatment to counteract sarin-induced brain damage in rats.
Filip Caisberger, Jaroslav Pejchal, Jan Misik, Jiri Kassa, Martin Valis

BMC Pharmacol Toxicol· June 2018

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In vitro skin decontamination of paraoxon - wet-type cleansing effect of selected detergents.
Ruzena Pavlikova, Jan Misik, Jiri Cabal, Jan Marek, Kamil Kuca

Cutan Ocul Toxicol· March 2018

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Activity of cholinesterases in a young and healthy middle-European population: Relevance for toxicology, pharmacology and clinical praxis.
Jana Zdarova Karasova, Zuzana Maderycova, Martina Tumova, Daniel Jun, Vit Rehacek, Jan Misik

Toxicol Lett· August 2017

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The Evaluation of the Reactivating and Neuroprotective Efficacy of Two Newly Prepared Bispyridinium Oximes (K305, K307) in Tabun-Poisoned Rats-A Comparison with Trimedoxime and the Oxime K203.
Jiri Kassa, Jan Misik, Jana Hatlapatkova, Jana Zdarova Karasova, Vendula Sepsova

Molecules· July 2017

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Development of 2-Methoxyhuprine as Novel Lead for Alzheimer's Disease Therapy.
Eva Mezeiova, Jan Korabecny, Vendula Sepsova, Martina Hrabinova, Petr Jost, Jan Misik

Molecules· July 2017

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A comparison of neuroprotective efficacy of two novel reactivators of acetylcholinesterase called K920 and K923 with the oxime K203 and trimedoxime in tabun-poisoned rats.
Jiri Kassa, Jan Misik, Jana Hatlapatkova, Jana Zdarova Karasova

Toxicol Mech Methods· March 2017

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Concentration of Donepezil in the Cerebrospinal Fluid of AD Patients: Evaluation of Dosage Sufficiency in Standard Treatment Strategy.
Martin Valis, Jiri Masopust, Oldrich Vysata, Jakub Hort, Rafael Dolezal, Jan Misik

Neurotox Res· January 2017

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Effects of novel tacrine-related cholinesterase inhibitors in the reversal of 3-quinuclidinyl benzilate-induced cognitive deficit in rats--Is there a potential for Alzheimer's disease treatment?
Jan Misik, Jan Korabecny, Eugenie Nepovimova, Alzbeta Kracmarova, Jiri Kassa

Neurosci Lett· January 2016

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The effects of novel 7-MEOTA-donepezil like hybrids and N-alkylated tacrine analogues in the treatment of quinuclidinyl benzilate-induced behavioural deficits in rats performing the multiple T-maze test.
Jan Misik, Jan Korabecny, Eugenie Nepovimova, Pavla Cabelova, Jiri Kassa

Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub· December 2015

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Translation of in vitro to in vivo pyridinium oxime potential in tabun poisoning.
Maja Katalinić, Nikolina Maček Hrvat, Jana Žďárová Karasová, Jan Misik, Zrinka Kovarik

Arh Hig Rada Toksikol· December 2015

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Self-expandable biodegradable biliary stents in porcine model.
Tomáš Grolich, Michal Crha, Ladislav Novotný, Zdeněk Kala, Aleš Hep

J Surg Res· February 2015

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Acute toxicity of some nerve agents and pesticides in rats.
Jan Misik, Ruzena Pavlikova, Jiri Cabal, Kamil Kuca

Drug Chem Toxicol· January 2015

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Cholinergic antagonist 3-quinuclidinyl benzilate - Impact on learning and memory in Wistar rats.
Jan Misik, Jan Vanek, Kamil Musilek, Jiri Kassa

Behav Brain Res· June 2014

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Evaluation of the potency of two novel bispyridinium oximes (K456, K458) in comparison with oxime K203 and trimedoxime to counteract tabun-induced neurotoxicity in rats.
Jiri Kassa, Jan Misik, Jana Z Karasova

Basic Clin Pharmacol Toxicol· September 2013

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A comparison of decontamination effects of commercially available detergents in rats pre-exposed to topical sulphur mustard.
Jan Misik, Petr Jost, Ruzena Pavlikova, Eva Vodakova, Jiri Cabal

Cutan Ocul Toxicol· June 2013

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Percutaneous toxicity and decontamination of soman, VX, and paraoxon in rats using detergents.
Jan Misík, Růžena Pavliková, Kamil Kuča

Arh Hig Rada Toksikol· June 2013

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Avian high-dose toxicity of cyanobacterial biomass.
Jiri Kral, Jiri Pikula, Hana Bandouchova, Veronika Damkova, Klara Hilscherova, Jan Misik

Neuro Endocrinol Lett· April 2013

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In vivo decontamination of the nerve agent VX using the domestic swine model.
Jan Misik, Michal Pavlik, Ladislav Novotny, Ruzena Pavlikova, Robert P Chilcott

Clin Toxicol (Phila)· November 2012

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