Publications by authors named "Jan Schaefer"

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The use of brain-specific biomarkers in urine for prediction of neurological outcome and extent of tissue damage following stroke.
Franziska Lieschke, Daniel T Marggrander, Maximilian Rauch, Jan Hendrik Schaefer, Ferdinand O Bohmann

Sci Rep· December 2025

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Case Report: Sustained biochemical remission following early initiation of odevixibat in an infant with monoallelic ABCB11 mutation and histologically confirmed PFIC2.
Thomas Kehler, Jan Thomas Schaefer, Katja Evert, Maren Zapke, Joachim Woelfle

Front Pediatr· December 2025

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Non-apoptotic caspase-8 is critical for orchestrating exaggerated inflammation during severe SARS-CoV-2 infection.
Stefanie M Bader, Lena Scherer, Reet Bhandari, Allan J Motyer, James P Cooney, Jan Schaefer

Nat Commun· November 2025

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Endoscopic Full-Thickness Resection Biopsy Using Ovesco Diagnostic FTRD® as a Tool to Diagnose Hirschsprung's Disease in Children: A Case Series.
Ronaldo A González García, Miriam Riedel, Adrian P Regensburger, Aline Rückel, Alexander Schnell, Jan Thomas Schaefer

Visc Med· November 2025

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Dual antiplatelet therapy increases intracerebral hemorrhage and edema after controlled cortical impact and can be partially encountered by 12/15-lipoxygenase inhibition.
Franziska Lieschke, Yi Zheng, Josephine Lok, Jan Hendrik Schaefer, Christian Foerch

J Cereb Blood Flow Metab· September 2025

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Symptoms, Imaging Features, Treatment Decisions, and Outcomes of Patients with Top of the Basilar Artery Syndrome: Experiences from a Comprehensive Stroke Center.
Franziska Lieschke, Maximilian Rauch, Bastian Roller, Jan Hendrik Schaefer, Martin A Schaller-Paule

Neurocrit Care· August 2025

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Lipid nanoparticle-delivered intrabodies for inhibiting necroptosis and pyroptosis.
Veerasikku Gopal Deepagan, Xiuquan Ma, Farzaneh Bazregari, Jiyi Pang, Jan Schaefer

Biochem J· August 2025

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Oral health status in children with chronic kidney disease, kidney transplantation, and nephrotic syndrome: a cross-sectional study.
Anna Beyer, Fabian Ebach, Heiko Reutter, Katja Sauerstein, Alina Christine Hilger, Jan Thomas Schaefer

Pediatr Nephrol· July 2025

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IL-1β drives SARS-CoV-2-induced disease independently of the inflammasome and pyroptosis signalling.
Stefanie M Bader, Lena Scherer, Jan Schaefer, James P Cooney, Liana Mackiewicz

Cell Death Differ· July 2025

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Coagulopathy, injury severity and bleeding progression but not prior antiplatelet and anticoagulation therapies drive prognosis in patients with moderate to severe traumatic brain injury.
Franziska Lieschke, Daniel T Marggrander, Konstantin D Kohlhase, Daniel Touma, Jan Hendrik Schaefer

Front Neurol· July 2025

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A novel PLpro inhibitor improves outcomes in a pre-clinical model of long COVID.
Stefanie M Bader, Dale J Calleja, Shane M Devine, Nathan W Kuchel, Bernadine G C Lu, Jan Schaefer

Nat Commun· April 2025

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Exploring the Link Between Renal Function Fluctuations Within the Physiological Range and Serum/CSF Levels of NfL, GFAP, tTAU, and UCHL1.
Kimberly Koerbel, Yavor Yalachkov, Tabea Rotter, Martin A Schaller-Paule, Jan Hendrik Schaefer

Int J Mol Sci· January 2025

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Recanalization Outcomes and Procedural Complications in Patients With Acute Ischemic Stroke and COVID-19 Receiving Endovascular Treatment.
João Pedro Marto, Davide Strambo, George Ntaios, Thanh N Nguyen, Pawel Wrona, Jan Hendrik Schaefer

J Stroke· January 2025

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Surgical infarct volume reduction and functional outcomes in patients with ischemic cerebellar stroke: results from a multicentric retrospective study.
Silvia Hernandez-Duran, Johannes Walter, Bedjan Behmanesh, Joshua D Bernstock, Marcus Czabanka, Jan Hendrik Schaefer

J Neurosurg· December 2024

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Progressive Kidney Failure by Angiotensinogen Inactivation in the Germline.
Florian J Wopperer, Eric Olinger, Antje Wiesener, Katharina A E Broeker, Karl X Knaup, Jan T Schaefer

Hypertension· September 2024

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Prevalence, recovery and phenotype of dysphagia in patients with ischaemic cerebellar stroke.
Jan Hendrik Schaefer, Felix Luft, Alexander Seiler, Elena Harborth, Sara Kaffenberger

Eur J Neurol· July 2024

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Necrosectomy Versus Stand-Alone Suboccipital Decompressive Craniectomy for the Management of Space-Occupying Cerebellar Infarctions-A Retrospective Multicenter Study.
Silvia Hernandez-Duran, Johannes Walter, Bedjan Behmanesh, Joshua D Bernstock, Marcus Czabanka, Jan Hendrik Schaefer

Neurosurgery· March 2024

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Functional Outcomes in Conservatively vs Surgically Treated Cerebellar Infarcts.
Sae-Yeon Won, Silvia Hernández-Durán, Bedjan Behmanesh, Joshua D Bernstock, Marcus Czabanka, Jan Hendrik Schaefer

JAMA Neurol· February 2024

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Feasibility and comparability of different platelet function tests in acute stroke with or without prior antiplatelet therapy.
Jan Hendrik Schaefer, Franziska Lieschke, Hans Urban, Ferdinand O Bohmann, Florian Gatzke

Front Neurol· February 2024

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Differences in characteristics between patients from Egypt and Germany presenting with lacunar stroke.
Mohamed Maged, Hany Aref, Nevine El Nahas, Eman Hamid, Mai Fathy, Jan Hendrik Schaefer

Sci Rep· December 2023

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Cerebellar Stroke Score and Grading Scale for the Prediction of Mortality and Outcomes in Ischemic Cerebellar Stroke.
Sae-Yeon Won, Ruzanna Melkonian, Bedjan Behmanesh, Joshua D Bernstock, Marcus Czabanka, Jan Hendrik Schaefer

Stroke· October 2023

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Relevance of dedicated multiple sclerosis serum biomarkers in predicting contrast enhancement with gadolinium: Results from the REDUCE-GAD trial.
Jan Hendrik Schaefer, Martin A Schaller-Paule, Katharina Wenger, Christoph Mayer, Ulrike Mann

Eur J Neurol· August 2023

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Frequency and impact of enteric hyperoxaluria in pediatric short bowel syndrome: a retrospective single centre study.
Jan Thomas Schaefer, Susanne Schulz-Heise, Aline Rueckel, Manfred Rauh, Joerg Juengert

Front Pediatr· July 2023

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A necroptosis-independent function of RIPK3 promotes immune dysfunction and prevents control of chronic LCMV infection.
Simon P Preston, Cody C Allison, Jan Schaefer, William Clow, Stefanie M Bader

Cell Death Dis· February 2023

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Killing in self-defense: proapoptotic drugs to eliminate intracellular pathogens.
Jan Schaefer, William Clow, Reet Bhandari, Mari Kimura, Lewis Williams

Curr Opin Immunol· December 2022

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