Publications by authors named "Jan Simak"

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Effects of an amustaline (S-303)/glutathione pathogen reduction system on the in vitro quality of plasma and platelets in treated whole blood.
M Reza Khoshi, Ayantu Jinfessa, Anais Pongerard, Michelle Gatmaitan, Melanie Sweeney, Jan Simak

Transfusion· November 2025

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Effect of concurrent pathogen reduction (amotosalen/UVA) and gamma/x-ray irradiation on biochemical characteristics of apheresis platelets in additive solution.
M Reza Khoshi, Andrey Skripchenko, Robel Seifu, Karen Byrne, K West-Mitchell, Jan Simak

Transfusion· January 2025

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Submicron immunoglobulin particles exhibit FcγRII-dependent toxicity linked to autophagy in TNFα-stimulated endothelial cells.
Wanida C Hollis, Sehrish Farooq, M Reza Khoshi, Mehulkumar Patel, Elena Karnaukhova, Jan Simak

Cell Mol Life Sci· August 2024

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Structural analysis of platelet fragments and extracellular vesicles produced by apheresis platelets during storage.
Silvia H De Paoli, Mehulkumar Patel, Oumsalama K Elhelu, Ivan D Tarandovskiy, Tseday Z Tegegn, Jan Simak

Blood Adv· January 2024

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Cell membrane disintegration and extracellular vesicle release in a model of different size and charge PAMAM dendrimers effects on cultured endothelial cells.
Mehulkumar Patel, Silvia H De Paoli, Oumsalama K Elhelu, Sehrish Farooq, Jan Simak

Nanotoxicology· June 2019

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An effective "three-in-one" screening assay for testing drug and nanoparticle toxicity in human endothelial cells.
Marcela Filipova, Oumsalama K Elhelu, Silvia H De Paoli, Zuzana Fremuntova, Tibor Mosko, Jan Simak

PLoS One· April 2019

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Hemoglobin oxidation-dependent reactions promote interactions with band 3 and oxidative changes in sickle cell-derived microparticles.
Sirsendu Jana, Michael Brad Strader, Fantao Meng, Wayne Hicks, Tigist Kassa, Jan Simak

JCI Insight· November 2018

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Dissecting the biochemical architecture and morphological release pathways of the human platelet extracellular vesiculome.
Silvia H De Paoli, Tseday Z Tegegn, Oumsalama K Elhelu, Michael B Strader, Mehulkumar Patel, Jan Simak

Cell Mol Life Sci· October 2018

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The effects of nanomaterials on blood coagulation in hemostasis and thrombosis.
Jan Simak, Silvia De Paoli

Wiley Interdiscip Rev Nanomed Nanobiotechnol· September 2017

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).
Daniel J Klionsky, Kotb Abdelmohsen, Akihisa Abe, Md Joynal Abedin, Hagai Abeliovich, Jan Simak

Autophagy· October 2016

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Characterization of procoagulant extracellular vesicles and platelet membrane disintegration in DMSO-cryopreserved platelets.
Tseday Z Tegegn, Silvia H De Paoli, Martina Orecna, Oumsalama K Elhelu, Samuel A Woodle, Jan Simak

J Extracell Vesicles· May 2016

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Subvisible Particle Content, Formulation, and Dose of an Erythropoietin Peptide Mimetic Product Are Associated With Severe Adverse Postmarketing Events.
Joseph Kotarek, Christine Stuart, Silvia H De Paoli, Jan Simak, Tsai-Lien Lin

J Pharm Sci· March 2016

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Expression of the cellular prion protein affects posttransfusion recovery and survival of red blood cells in mice.
Hana Glier, Jan Simak, Martin Panigaj, Monique P Gelderman, Jaroslav G Vostal

Transfusion· November 2015

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First demonstration of transmissible spongiform encephalopathy-associated prion protein (PrPTSE) in extracellular vesicles from plasma of mice infected with mouse-adapted variant Creutzfeldt-Jakob disease by in vitro amplification.
Paula Saá, Oksana Yakovleva, Jorge de Castro, Irina Vasilyeva, Silvia H De Paoli, Jan Simak

J Biol Chem· October 2014

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The effect of protein corona composition on the interaction of carbon nanotubes with human blood platelets.
Silvia H De Paoli, Lukas L Diduch, Tseday Z Tegegn, Martina Orecna, Michael B Strader, Jan Simak

Biomaterials· August 2014

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Toxicity of carboxylated carbon nanotubes in endothelial cells is attenuated by stimulation of the autophagic flux with the release of nanomaterial in autophagic vesicles.
Martina Orecna, Silvia H De Paoli, Olga Janouskova, Tseday Z Tegegn, Marcela Filipova, Jan Simak

Nanomedicine· July 2014

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Nanoparticle size and surface charge determine effects of PAMAM dendrimers on human platelets in vitro.
Marina A Dobrovolskaia, Anil K Patri, Jan Simak, Jennifer B Hall, Jana Semberova

Mol Pharm· March 2012

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Carbon nanotubes activate store-operated calcium entry in human blood platelets.
Silvia H De Paoli Lacerda, Jana Semberova, Karel Holada, Olga Simakova, Steven D Hudson, Jan Simak

ACS Nano· July 2011

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Underestimation of the expression of cellular prion protein on human red blood cells.
Martin Panigaj, Adela Brouckova, Hana Glierova, Eva Dvorakova, Jan Simak

Transfusion· May 2011

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Meeting report on protein particles and immunogenicity of therapeutic proteins: filling in the gaps in risk evaluation and mitigation.
John Carpenter, Barry Cherney, Anthony Lubinecki, Stacey Ma, Ewa Marszal, Jan Simak

Biologicals· September 2010

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Carbon nanotubes activate blood platelets by inducing extracellular Ca2+ influx sensitive to calcium entry inhibitors.
Jana Semberova, Silvia H De Paoli Lacerda, Olga Simakova, Karel Holada, Monique P Gelderman, Jan Simak

Nano Lett· September 2009

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Flow cytometric analysis of cell membrane microparticles.
Monique P Gelderman, Jan Simak

Methods Mol Biol· February 2009

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Reduced erythroid cell and erythropoietin production in response to acute anemia in prion protein-deficient (Prnp-/-) mice.
Jan H Zivny, Monique P Gelderman, Fei Xu, John Piper, Karel Holada, Jan Simak

Blood Cells Mol Dis· August 2008

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Adverse effects of fullerenes on endothelial cells: fullerenol C60(OH)24 induced tissue factor and ICAM-I membrane expression and apoptosis in vitro.
Monique P Gelderman, Olga Simakova, Jeffrey D Clogston, Anil K Patri, Sheena F Siddiqui, Jan Simak

Int J Nanomedicine· June 2008

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Divergent expression of cellular prion protein on blood cells of human and nonhuman primates.
Karel Holada, Jan Simak, Paul Brown, Jaroslav G Vostal

Transfusion· December 2007

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