Publications by authors named "Jan Simper"

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NR4A nuclear receptor expression in human macrophages mediates apoptosis and controls Mycobacterium tuberculosis growth.
Jan D Simper, Natalie Jarvis, Susanta Pahari, Daniella Ortega, Abul Azad

J Immunol· December 2025

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Cutting Edge: Cytosolic Receptor AIM2 Is Induced by Peroxisome Proliferator-activated Receptor γ following Mycobacterium tuberculosis Infection of Human Macrophages but Does Not Contribute to IL-1β Release.
Eusondia Arnett, Jade Wolff, Chrissy M Leopold Wager, Jan Simper, Jeanine L Badrak

J Immunol· March 2024

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A new tractable method for generating human alveolar macrophage-like cells to study lung inflammatory processes and diseases.
Susanta Pahari, Eusondia Arnett, Jan Simper, Abul Azad, Israel Guerrero-Arguero

mBio· August 2023

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A new tractable method for generating Human Alveolar Macrophage Like cells in vitro to study lung inflammatory processes and diseases.
Susanta Pahari, Eusondia Arnett, Jan Simper, Abul Azad, Israel Guerrero-Arguero

bioRxiv· April 2023

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Activation of transcription factor CREB in human macrophages by Mycobacterium tuberculosis promotes bacterial survival, reduces NF-kB nuclear transit and limits phagolysosome fusion by reduced necroptotic signaling.
Chrissy M Leopold Wager, Jordan R Bonifacio, Jan Simper, Adrian A Naoun, Eusondia Arnett

PLoS Pathog· March 2023

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Resistance and Susceptibility Immune Factors at Play during Infection of Macrophages.
Jan D Simper, Esteban Perez, Larry S Schlesinger, Abul K Azad

Pathogens· October 2022

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Iterative, multiplexed CRISPR-mediated gene editing for functional analysis of complex protease gene clusters.
LuLu K Callies, Daniel Tadeo, Jan Simper, Thomas H Bugge, Roman Szabo

J Biol Chem· November 2019

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