Publications by authors named "Jan Sperl"

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Genetic drivers of liver cirrhosis: The role of SERPINA1 and PNPLA3 variants in disease onset and progression.
Mikolas Holinka, Sona Frankova, Svetlana Adamcova Selcanova, Lubomir Skladany, Ondrej Fabian, Jan Sperl

PLoS One· September 2025

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Severe alpha-1 antitrypsin deficiency is associated with a higher risk of complications after first decompensation than other aetiologies of cirrhosis.
Lorenz Balcar, Malin Fromme, Naomi Kappe, Benedikt Schaefer, Soňa Fraňková, Jan Sperl

JHEP Rep· June 2025

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Longitudinal Evaluation of Individuals With Severe Alpha-1 Antitrypsin Deficiency (Pi∗ZZ Genotype).
Malin Fromme, Audrey Payancé, Mattias Mandorfer, Katrine H Thorhauge, Monica Pons, Jan Sperl

Gastroenterology· February 2025

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Correction: Exome sequencing reveals IFT172 variants in patients with non-syndromic cholestatic liver disease.
Magdaléna Neřoldová, Elżbieta Ciara, Janka Slatinská, Soňa Fraňková, Petra Lišková

PLoS One· January 2025

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Alcohol consumption and liver phenotype of individuals with alpha-1 antitrypsin deficiency.
Malin Fromme, Carolin V Schneider, Nurdan Guldiken, Samira Amzou, Yizhao Luo, Jan Sperl

Liver Int· October 2024

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Impact of multiple primary cancers on overall survival of patients with hepatocellular carcinoma.
Petr Hříbek, Sona Fraňková, Johana Klasová, Klára Chmelová, Lucie Miková

Neoplasma· June 2024

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Alpha-1 Antitrypsin Augmentation and the Liver Phenotype of Adults With Alpha-1 Antitrypsin Deficiency (Genotype Pi∗ZZ).
Malin Fromme, Karim Hamesch, Carolin V Schneider, Mattias Mandorfer, Monica Pons, Jan Sperl

Clin Gastroenterol Hepatol· February 2024

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[Acute kidney injury in patients with cirrhosis - practical summary].
Kateřina Množil Střídová, Soňa Fraňková, Jan Šperl

Vnitr Lek· November 2023

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[Diagnosis and therapy of chronic hepatitis D: Czech national guideline].
Petr Husa, Jan Šperl, Petr Urbánek, Soňa Fraňková, Pavel Dlouhý

Klin Mikrobiol Infekc Lek· September 2023

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Exome sequencing reveals IFT172 variants in patients with non-syndromic cholestatic liver disease.
Magdaléna Neřoldová, Elżbieta Ciara, Janka Slatinská, Soňa Fraňková, Petra Lišková

PLoS One· July 2023

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Predictors of Significant Liver Fibrosis in People with Chronic Hepatitis C Who Inject Drugs in the Czech Republic.
Sona Frankova, Nikola Uzlova, Dusan Merta, Veronika Pitova, Jan Sperl

Life (Basel)· April 2023

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Low Frequency of Cancer-Predisposition Gene Mutations in Liver Transplant Candidates with Hepatocellular Carcinoma.
Klara Horackova, Sona Frankova, Petra Zemankova, Petr Nehasil, Marta Cerna, Jan Sperl

Cancers (Basel)· December 2022

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HCV Elimination in Central Europe with Particular Emphasis on Microelimination in Prisons.
Robert Flisiak, Dorota Zarębska-Michaluk, Egle Ciupkeviciene, Sylvia Drazilova, Sona Frankova, Jan Sperl

Viruses· February 2022

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Alpha-1 Antitrypsin and Hepatocellular Carcinoma in Liver Cirrhosis: MZ or MS Genotype Carriage Decreases the Risk.
Zuzana Rabekova, Sona Frankova, Milan Jirsa, Magdalena Neroldova, Mariia Lunova, Jan Sperl

Int J Mol Sci· September 2021

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Is elimination of HCV in 2030 realistic in Central Europe.
Robert Flisiak, Dorota Zarębska-Michaluk, Sona Frankova, Ivica Grgurevic, Bela Hunyady, Jan Sperl

Liver Int· June 2021

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Therapy of chronic hepatitis C in people who inject drugs: focus on adherence.
Sona Frankova, Zuzana Jandova, Gabriela Jinochova, Miluse Kreidlova, Dusan Merta, Jan Sperl

Harm Reduct J· June 2021

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Liver stiffness measured by two-dimensional shear-wave elastography predicts hepatic vein pressure gradient at high values in liver transplant candidates with advanced liver cirrhosis.
Sona Frankova, Mariia Lunova, Halima Gottfriedova, Renata Senkerikova, Magdalena Neroldova, Jan Sperl

PLoS One· May 2021

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Chronic hepatitis C virus infection in the Czech Republic and Slovakia: an analysis of patient and virus characteristics.
Lubomír Skladaný, Marian Oltman, Soňa Fraňková, Sylvia Dražilová, Petr Husa

Int J Public Health· December 2020

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[Rizikové faktory a surveillance hepatocelulárního karcinomu].
Soňa Fraňková, Jan Šperl

Vnitr Lek· April 2020

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PNPLA3 rs738409 G allele carriers with genotype 1b HCV cirrhosis have lower viral load but develop liver failure at younger age.
Renata Senkerikova, Sona Frankova, Milan Jirsa, Miluse Kreidlova, Dusan Merta, Jan Sperl

PLoS One· March 2020

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How close are we to hepatitis C virus elimination in Central Europe?
Robert Flisiak, Sona Frankova, Ivica Grgurevic, Bela Hunyady, Peter Jarcuska, Jan Sperl

Clin Exp Hepatol· February 2020

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Elbasvir/grazoprevir in women with hepatitis C virus infection taking oral contraceptives or hormone replacement therapy.
Christophe Hézode, Paul Kwo, Jan Sperl, Peggy Hwang, Jianmin Long

Int J Womens Health· November 2019

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IL28B rs12979860 T allele protects against CMV disease in liver transplant recipients in the post-prophylaxis and late period.
Klara Chmelova, Sona Frankova, Milan Jirsa, Magdalena Neroldova, Eva Sticova, Jan Sperl

Transpl Infect Dis· August 2019

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Chronic hepatitis C in the Czech Republic: Forecasting the disease burden.
Soňa Fraňková, Petr Urbánek, Petr Husa, Vratislav Němeček, Homie Razavi

Cent Eur J Public Health· June 2019

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Patient-reported outcomes in individuals with hepatitis C virus infection treated with elbasvir/grazoprevir.
Xinyi Ng, Chizoba Nwankwo, Jean Marie Arduino, Shelby Corman, Kathryn Eilene Lasch, Jan Sperl

Patient Prefer Adherence· December 2018

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