Publications by authors named "Jan Stindt"

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Bile acid receptor Tgr5 prevents macrophage hyperinflammation during bacterial sepsis through metabolic and epigenetic silencing.
Maria Reich, Tobias Franz, Haifeng C Xu, Paulina Philippski, Jan Stindt

iScience· December 2025

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A farnesoid X receptor T296I variant disrupts ligand-induced FXR activation and thus bile acid transport in progressive familial intrahepatic cholestasis.
Annika Behrendt, Alex Bastianelli, Jan Stindt, Eva-Doreen Pfister, Malte Sgodda

J Biol Chem· November 2025

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Cell-based BSEP trans-inhibition: A novel, non-invasive test for diagnosis of antibody-induced BSEP deficiency.
Jan Stindt, Carola Dröge, Elke Lainka, Simone Kathemann, Eva-Doreen Pfister

JHEP Rep· July 2023

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Extrahepatic manifestations of progressive familial intrahepatic cholestasis syndromes: Presentation of a case series and literature review.
Eva-Doreen Pfister, Carola Dröge, Roman Liebe, Amelie Stalke, Nicole Buhl, Jan Stindt

Liver Int· May 2022

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Swelling-induced upregulation of miR-141-3p inhibits hepatocyte proliferation.
Nils Bardeck, Martha Paluschinski, Mirco Castoldi, Claus Kordes, Boris Görg, Jan Stindt

JHEP Rep· April 2022

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Autoantibody formation against a canalicular epitope found in a patient with acute intrahepatic cholestasis with PFIC-like presentation.
Jonas Schumacher, Toni Herta, Jan Stindt, Verena Keitel, Thomas Berg

JHEP Rep· February 2022

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Evidence for a credit-card-swipe mechanism in the human PC floppase ABCB4.
Martin Prescher, Michele Bonus, Jan Stindt, Verena Keitel-Anselmino, Sander H J Smits

Structure· October 2021

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Downregulation of TGR5 (GPBAR1) in biliary epithelial cells contributes to the pathogenesis of sclerosing cholangitis.
Maria Reich, Lina Spomer, Caroline Klindt, Katharina Fuchs, Jan Stindt

J Hepatol· September 2021

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Influence of Rapid Heat Treatment on the Shrinkage and Strength of High-Performance Concrete.
Jan Stindt, Patrick Forman, Peter Mark

Materials (Basel)· July 2021

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Diagnosis and management of secondary causes of steatohepatitis.
Roman Liebe, Irene Esposito, Hans H Bock, Stephan Vom Dahl, Jan Stindt

J Hepatol· June 2021

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Dubin-Johnson Syndrome as Differential Diagnosis for Neonatal Cholestasis.
Norman Junge, Imeke Goldschmidt, Jessica Wiegandt, Christoph Leiskau, Frauke Mutschler, Jan Stindt

J Pediatr Gastroenterol Nutr· May 2021

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The G Protein-Coupled Bile Acid Receptor TGR5 (Gpbar1) Modulates Endothelin-1 Signaling in Liver.
Caroline Klindt, Maria Reich, Birte Hellwig, Jan Stindt, Jörg Rahnenführer

Cells· November 2019

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Bile Acid-Activated Receptors: GPBAR1 (TGR5) and Other G Protein-Coupled Receptors.
Verena Keitel, Jan Stindt, Dieter Häussinger

Handb Exp Pharmacol· September 2019

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Nuclear Translocation of RELB Is Increased in Diseased Human Liver and Promotes Ductular Reaction and Biliary Fibrosis in Mice.
Christin Elßner, Benjamin Goeppert, Thomas Longerich, Anna-Lena Scherr, Jan Stindt

Gastroenterology· March 2019

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Allogeneic haematopoietic stem cell transplantation eliminates alloreactive inhibitory antibodies after liver transplantation for bile salt export pump deficiency.
Florian Brinkert, Ieva Pukite, Dorothee Krebs-Schmitt, Andrea Briem-Richter, Jan Stindt

J Hepatol· October 2018

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Analysis of the Bile Salt Export Pump (ABCB11) Interactome Employing Complementary Approaches.
Susanne Przybylla, Jan Stindt, Diana Kleinschrodt, Jan Schulte Am Esch, Dieter Häussinger

PLoS One· August 2017

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Partial external biliary diversion in bile salt export pump deficiency: Association between outcome and mutation.
Philipp Ellinger, Jan Stindt, Carola Dröge, Katharina Sattler, Claudia Stross

World J Gastroenterol· August 2017

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High affinity anti-BSEP antibodies after liver transplantation for PFIC-2 - Successful treatment with immunoadsorption and B-cell depletion.
Ralf Kubitz, Carola Dröge, Stefanie Kluge, Jan Stindt, Claudia Stross

Pediatr Transplant· November 2016

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Bile Acids Act as Soluble Host Restriction Factors Limiting Cytomegalovirus Replication in Hepatocytes.
Anna-Kathrin Schupp, Mirko Trilling, Stephanie Rattay, Vu Thuy Khanh Le-Trilling, Katrin Haselow, Jan Stindt

J Virol· August 2016

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Bile salt export pump-reactive antibodies form a polyclonal, multi-inhibitory response in antibody-induced bile salt export pump deficiency.
Jan Stindt, Stefanie Kluge, Carola Dröge, Verena Keitel, Claudia Stross

Hepatology· February 2016

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Autoimmune BSEP disease: disease recurrence after liver transplantation for progressive familial intrahepatic cholestasis.
Ralf Kubitz, Carola Dröge, Stefanie Kluge, Claudia Stross, Nathalie Walter, Jan Stindt

Clin Rev Allergy Immunol· June 2015

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A mutation within the extended X loop abolished substrate-induced ATPase activity of the human liver ATP-binding cassette (ABC) transporter MDR3.
Marianne Kluth, Jan Stindt, Carola Dröge, Doris Linnemann, Ralf Kubitz

J Biol Chem· February 2015

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Genetic variations of bile salt transporters.
Ralf Kubitz, Carola Dröge, Stefanie Kluge, Jan Stindt, Dieter Häussinger

Drug Discov Today Technol· June 2014

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Hepatitis B and D viruses exploit sodium taurocholate co-transporting polypeptide for species-specific entry into hepatocytes.
Yi Ni, Florian A Lempp, Stefan Mehrle, Shirin Nkongolo, Christina Kaufman, Jan Stindt

Gastroenterology· April 2014

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A novel mutation within a transmembrane helix of the bile salt export pump (BSEP, ABCB11) with delayed development of cirrhosis.
Jan Stindt, Philipp Ellinger, Katrin Weissenberger, Carola Dröge, Diran Herebian

Liver Int· November 2013

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