Publications by authors named "Jan T Andersen"

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Impact of antibody Fc engineering on translational pharmacology, and safety: insights from industry case studies.
Frank R Brennan, J Ryan Polli, Jean Sathish, Melissa Ramones, Babette Wolf, Jan Terje Andersen

MAbs· December 2025

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Systematic benchmarking of mass spectrometry-based antibody sequencing reveals methodological biases.
Maria Chernigovskaya, Khang Lê Quý, Maria Stensland, Sachin Singh, Rowan Nelson, Jan Terje Andersen

Cell Syst· November 2025

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Tailored collagen binding of albumin-fused hyperactive coagulation factor IX dictates in vivo distribution and functional properties.
Kristin Hovden Aaen, Maria Francesca Testa, Jeannette Nilsen, Rebecca Tarantino, Cesare Canepari, Mari Nyquist-Andersen, Jan Terje Andersen

Nat Commun· September 2025

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Advanced microbiome therapeutics for oral delivery of peptides and proteins: Advances, challenges, and opportunities.
Hitesh P Gelli, Ruben Vazquez-Uribe, Stephen T Buckley, Jan Terje Andersen, Morten Otto Alexander Sommer

Adv Drug Deliv Rev· July 2025

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Exploiting FcRn engagement of an albumin-CpG oligonucleotide covalent conjugate for potent TLR9 immune induction.
Diego Pilati, Eugene Kusi Agyei, Marwa Elkhashab, Elisabeth Fuchs, Ian Helstrup Nielsen, Jan Terje Andersen

J Biol Chem· June 2025

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Identification of a direct interaction between the Fab domains of IgG antibodies and human FcRn upon IgG-FcRn complex formation.
Esben Trabjerg, Jeannette Nilsen, Torleif Tollefsrud Gjølberg, Jan Terje Andersen, Alexander Leitner

Commun Biol· June 2025

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Targeting the Neonatal Fc Receptor in Autoimmune Diseases: Pipeline and Progress.
Torleif Tollefsrud Gjølberg, Simone Mester, Gaia Calamera, Jenny Skjermo Telstad, Inger Sandlie, Jan Terje Andersen

BioDrugs· May 2025

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An intranasal subunit vaccine induces protective systemic and mucosal antibody immunity against respiratory viruses in mouse models.
Aina Karen Anthi, Anette Kolderup, Eline Benno Vaage, Malin Bern, Sopisa Benjakul, Mari Nyquist-Andersen, Jan Terje Andersen

Nat Commun· May 2025

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Enhanced plasma half-life and efficacy of engineered human albumin-fused GLP-1 despite enzymatic cleavage of its C-terminal end.
Jeannette Nilsen, Kristin Hovden Aaen, Sopisa Benjakul, Fulgencio Ruso-Julve, Thomas Uwe Greiner, Jan Terje Andersen

Commun Biol· May 2025

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Engineering of anticancer human immunoglobulin A equipped with albumin for enhanced plasma half-life.
Simone Mester, Chilam Chan, Marta Lustig, Stian Foss, J H Marco Jansen, Jan Terje Andersen

PNAS Nexus· February 2025

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Sialylation inhibition improves macrophage mediated tumor cell phagocytosis of breast cancer cells triggered by therapeutic antibodies of different isotypes.
Marta Lustig, Christoph Hahn, Marie Leangen Herigstad, Jan Terje Andersen, Jeanette H W Leusen

Front Oncol· November 2024

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Engineering of pH-dependent antigen binding properties for toxin-targeting IgG1 antibodies using light-chain shuffling.
Tulika Tulika, Fulgencio Ruso-Julve, Shirin Ahmadi, Anne Ljungars, Esperanza Rivera-de-Torre, Jan Terje Andersen

Structure· September 2024

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Biophysical cartography of the native and human-engineered antibody landscapes quantifies the plasticity of antibody developability.
Habib Bashour, Eva Smorodina, Matteo Pariset, Jahn Zhong, Rahmad Akbar, Jan Terje Andersen

Commun Biol· July 2024

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Insight into the avidity-affinity relationship of the bivalent, pH-dependent interaction between IgG and FcRn.
Johannes Reusch, Jan Terje Andersen, Ulrich Rant, Tilman Schlothauer

MAbs· June 2024

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Human IgG Fc-engineering for enhanced plasma half-life, mucosal distribution and killing of cancer cells and bacteria.
Stian Foss, Siri A Sakya, Leire Aguinagalde, Marta Lustig, Jutamas Shaughnessy, Jan Terje Andersen

Nat Commun· March 2024

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Phage display assisted discovery of a pH-dependent anti-α-cobratoxin antibody from a natural variable domain library.
Tulika Tulika, Rasmus W Pedersen, Charlotte Rimbault, Shirin Ahmadi, Esperanza Rivera-de-Torre, Jan Terje Andersen

Protein Sci· December 2023

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A pan-SARS-CoV-2-specific soluble angiotensin-converting enzyme 2-albumin fusion engineered for enhanced plasma half-life and needle-free mucosal delivery.
Sopisa Benjakul, Aina Karen Anthi, Anette Kolderup, Marina Vaysburd, Heidrun Elisabeth Lode, Mari Nyquist-Andersen, Jan Terje Andersen

PNAS Nexus· December 2023

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Pharmaceutical compounding and storage of faricimab in a syringe for intravitreal injection do not impair stability and bi-specific binding properties.
Øystein Kalsnes Jørstad, Stian Foss, Torleif Tollefsrud Gjølberg, Simone Mester, Mari Nyquist-Andersen, Jan Terje Andersen

Int J Retina Vitreous· November 2023

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Disruption of the sialic acid/Siglec-9 axis improves antibody-mediated neutrophil cytotoxicity towards tumor cells.
Marta Lustig, Chilam Chan, J H Marco Jansen, Maria Bräutigam, Max A Kölling, Jan Terje Andersen

Front Immunol· June 2023

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Antibody blockade of Jagged1 attenuates choroidal neovascularization.
Torleif Tollefsrud Gjølberg, Jonas Aakre Wik, Hanna Johannessen, Stig Krüger, Nicola Bassi, Jan Terje Andersen

Nat Commun· May 2023

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Cytosolic antibody receptor TRIM21 is required for effective tau immunotherapy in mouse models.
Aamir S Mukadam, Lauren V C Miller, Annabel E Smith, Marina Vaysburd, Siri A Sakya, Jan Terje Andersen

Science· March 2023

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Assessing developability early in the discovery process for novel biologics.
Monica L Fernández-Quintero, Anne Ljungars, Franz Waibl, Victor Greiff, Jan Terje Andersen

MAbs· February 2023

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Contribution of the ex vivo placental perfusion model in understanding transplacental immunoglobulin G transfer.
Kine Marita Knudsen Sand, Michael M Gruber, Inger Sandlie, Line Mathiesen, Jan Terje Andersen

Placenta· September 2022

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Breakthrough infections with the omicron and delta variants of SARS-CoV-2 result in similar re-activation of vaccine-induced immunity.
Arne Søraas, Gunnveig Grødeland, Beathe Kiland Granerud, Thor Ueland, Andreas Lind, Jan Terje Andersen

Front Immunol· September 2022

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Biophysical differences in IgG1 Fc-based therapeutics relate to their cellular handling, interaction with FcRn and plasma half-life.
Torleif Tollefsrud Gjølberg, Rahel Frick, Simone Mester, Stian Foss, Algirdas Grevys, Jan Terje Andersen

Commun Biol· August 2022

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