Publications by authors named "Jan Topinka"

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P-Postlabeling Analysis of DNA Adducts.
Alena Milcova, Volker M Arlt, Jan Topinka

Methods Mol Biol· November 2025

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Associations between air pollution and relative leukocyte telomere length among northern Swedish adults based on findings from the Betula study.
Wasif Raza, Sara Pudas, Katja M Kanninen, Erin Flanagan, Sofie Degerman, Jan Topinka

Sci Rep· September 2025

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Correction: Associations of environmental pollution with pro-oxidant, antioxidant and inflammatory markers in pregnant mothers and newborns.
Antonin Ambroz, Jiri Klema, Andrea Rossnerova, Alena Milcova, Anna Pastorkova, Jan Topinka

Front Toxicol· July 2025

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Traffic-related ultrafine particles influence gene regulation in olfactory mucosa cells altering PI3K/AKT signaling.
Laura Mussalo, Alexey M Afonin, Tana Zavodna, Zdenek Krejcik, Katerina Honkova, Jan Topinka

Environ Int· May 2025

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Traffic-related diesel pollution particles impair the lysosomal functions of human iPSC-derived microglia.
Sohvi Ohtonen, Henna Jäntti, Luca Giudice, Ahmed Mohamed, Anastasia Shakirzyanova, Jan Topinka

Environ Int· May 2025

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Biomarkers of exposure to polycyclic aromatic hydrocarbons in urine of municipal police officers: impact of inhalation on total exposure.
Veronika Gomersall, Katerina Ciglova, Ondrej Parizek, Andrea Rössnerova, Pavel Rössner, Jan Topinka

Environ Sci Pollut Res Int· April 2025

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Associations of environmental pollution with pro-oxidant, antioxidant and inflammatory markers in pregnant mothers and newborns.
Antonin Ambroz, Jiri Klema, Andrea Rossnerova, Alena Milcova, Anna Pastorkova, Jan Topinka

Front Toxicol· April 2025

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Importance of sub-23 nm particles in traffic environments: Particle number emission factors and extrathoracic deposition doses.
Henna Lintusaari, Teemu Lepistö, Sanna Saarikoski, Laura Salo, Ville Silvonen, Jan Topinka

Environ Pollut· March 2025

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Carcinogenicity of automotive gasoline and some oxygenated gasoline additives.
Michelle C Turner, Lode Godderis, Pascal Guénel, Nancy Hopf, Betzabet Quintanilla-Vega, Jan Topinka

Lancet Oncol· March 2025

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Portable emissions toxicity system: Evaluating the toxicity of emissions or polluted air by exposure of cell cultures at air-liquid interface in a compact field-deployable setup.
Michal Vojtisek-Lom, Lubos Dittrich, Martin Pechout, Tereza Cervena, Anezka Vimrova, Jan Topinka

Sci Total Environ· January 2025

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Comparative Study of Functionalized Carbosilane Dendrimers for siRNA Delivery: Synthesis, Cytotoxicity, and Biophysical Properties.
Monika Müllerová, Piotr Tarach, Tomáš Strašák, Petra Cuřínová, Roman Petrickovic, Jan Topinka

ACS Omega· January 2025

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Transcriptomic and epigenomic profiling reveals altered responses to diesel emissions in Alzheimer's disease both in vitro and in population-based data.
Liudmila Saveleva, Tereza Cervena, Claudia Mengoni, Michal Sima, Zdenek Krejcik, Jan Topinka

Alzheimers Dement· December 2024

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Genome-modified Caenorhabditis elegans expressing the human cytochrome P450 (CYP1A1 and CYP1A2) pathway: An experimental model for environmental carcinogenesis and pharmacological research.
Yuzhi Chen, Yang Jiang, Nirujah Sarvanantharajah, Orapan Apirakkan, Mengqi Yang, Jan Topinka

Environ Int· December 2024

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Traffic-related ultrafine particles impair mitochondrial functions in human olfactory mucosa cells - Implications for Alzheimer's disease.
Laura Mussalo, Riikka Lampinen, Simone Avesani, Táňa Závodná, Zdeněk Krejčík, Jan Topinka

Redox Biol· September 2024

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Exposure to source-specific air pollution in residential areas and its association with dementia incidence: a cohort study in Northern Sweden.
Anna Oudin, Wasif Raza, Erin Flanagan, David Segersson, Pasi Jalava, Jan Topinka

Sci Rep· July 2024

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Transcriptional and phenotypical alterations associated with a gradual benzo[a]pyrene-induced transition of human bronchial epithelial cells into mesenchymal-like cells.
Martina Hýžďalová, Jiřina Procházková, Nicol Straková, Kateřina Pěnčíková, Simona Strapáčová, Jan Topinka

Environ Toxicol Pharmacol· April 2024

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Emissions from modern engines induce distinct effects in human olfactory mucosa cells, depending on fuel and aftertreatment.
Laura Mussalo, Simone Avesani, Muhammad Ali Shahbaz, Táňa Závodná, Liudmila Saveleva, Jan Topinka

Sci Total Environ· December 2023

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Human-derived air-liquid interface cultures decipher Alzheimer's disease-SARS-CoV-2 crosstalk in the olfactory mucosa.
Muhammad Ali Shahbaz, Suvi Kuivanen, Riikka Lampinen, Laura Mussalo, Tomáš Hron, Jan Topinka

J Neuroinflammation· December 2023

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The Genotoxicity of Organic Extracts from Particulate Emissions Produced by Neat Gasoline (E0) and a Gasoline-Ethanol Blend (E15) in BEAS-2B Cells.
Helena Libalova, Tana Zavodna, Fatima Elzeinova, Hana Barosova, Tereza Cervena, Jan Topinka

J Xenobiot· December 2023

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Lactose-Functionalized Carbosilane Glycodendrimers Are Highly Potent Multivalent Ligands for Galectin-9 Binding: Increased Glycan Affinity to Galectins Correlates with Aggregation Behavior.
Monika Müllerová, Michaela Hovorková, Táňa Závodná, Lucie Červenková Št Astná, Alena Krupková, Jan Topinka

Biomacromolecules· November 2023

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Particle lung deposited surface area (LDSA) size distributions in different urban environments and geographical regions: Towards understanding of the PM dose-response.
Teemu Lepistö, Henna Lintusaari, Anna Oudin, Luis M F Barreira, Jarkko V Niemi, Jan Topinka

Environ Int· October 2023

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Assessment of organohalogenated pollutants in breast milk from the Czech Republic.
Ondrej Parizek, Tomas Gramblicka, Denisa Parizkova, Andrea Polachova, Kamila Bechynska, Jan Topinka

Sci Total Environ· May 2023

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Effects of various environments on epigenetic settings and chromosomal damage.
Andrea Rossnerova, Fatima Elzeinova, Irena Chvojkova, Katerina Honkova, Michal Sima, Jan Topinka

Environ Pollut· April 2023

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High aspect ratio nanomaterial-induced macrophage polarization is mediated by changes in miRNA levels.
Johanna Samulin Erdem, Táňa Závodná, Torunn K Ervik, Øivind Skare, Tomáš Hron, Jan Topinka

Front Immunol· February 2023

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Maternal Diet Quality and the Health Status of Newborns.
Jitka Pavlikova, Antonin Ambroz, Katerina Honkova, Irena Chvojkova, Radim J Sram, Jan Topinka

Foods· December 2022

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