Publications by authors named "Janet Greeson"

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Dimethyl-carbamic acid 2,3-Bis-Dimethylcarbamoyloxy-6-(4-Ethyl-Piperazine-1-Carbonyl)-phenyl ester: a novel multi-target therapeutic approach to neuroprotection.
Laurent Lecanu, Laurent Tillement, Althea McCourty, Georges Rammouz, Wenguo Yao, Janet Greeson

Med Chem· May 2010

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Identification of a benzamide derivative that inhibits stress-induced adrenal corticosteroid synthesis.
Jing Xu, Laurent Lecanu, Matthew Tan, Janet Greeson, Vassilios Papadopoulos

Molecules· September 2009

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Caprospinol: moving from a neuroactive steroid to a neurotropic drug.
Laurent Lecanu, Laurent Tillement, Georges Rammouz, Jean Paul Tillement, Janet Greeson

Expert Opin Investig Drugs· March 2009

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The benzamide derivative N-[1-(7-tert-Butyl-1H-indol-3-ylmethyl)-2-(4-cyclopropanecarbonyl-3-methyl-piperazin-1-yl)-2-oxo-ethyl]-4-nitro-benzamide (SP-10) reduces HIV-1 infectivity in vitro by modifying actin dynamics.
Jing Xu, Laurent Lecanu, Matthew Tan, Wenguo Yao, Janet Greeson

Antivir Chem Chemother· April 2007

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3D QSAR studies of AChE inhibitors based on molecular docking scores and CoMFA.
Nagaraju Akula, Laurent Lecanu, Janet Greeson, Vassilios Papadopoulos

Bioorg Med Chem Lett· December 2006

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The spirostenol (22R, 25R)-20alpha-spirost-5-en-3beta-yl hexanoate blocks mitochondrial uptake of Abeta in neuronal cells and prevents Abeta-induced impairment of mitochondrial function.
Laurent Tillement, Laurent Lecanu, Wenguo Yao, Janet Greeson, Vassilios Papadopoulos

Steroids· August 2006

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Beta-amyloid and oxidative stress jointly induce neuronal death, amyloid deposits, gliosis, and memory impairment in the rat brain.
Laurent Lecanu, Janet Greeson, Vassilios Papadopoulos

Pharmacology· February 2006

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Methodology for multi-site ligand-protein docking identification developed for the optimization of spirostenol inhibition of beta-amyloid-induced neurotoxicity.
Gary L Teper, Laurent Lecanu, Janet Greeson, Vassilios Papadopoulos

Chem Biodivers· November 2005

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Identification, design, synthesis, and pharmacological activity of (4-ethyl-piperazin-1-yl)-phenylmethanone derivatives with neuroprotective properties against beta-amyloid-induced toxicity.
Laurent Lecanu, Wenguo Yao, Alexander Piechot, Janet Greeson, Dimitrios Tzalis

Neuropharmacology· July 2005

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Local anesthetic procaine protects rat pheochromocytoma PC12 cells against beta-amyloid-induced neurotoxicity.
Laurent Lecanu, Yao Wenguo, Jing Xu, Janet Greeson, Vassilios Papadopoulos

Pharmacology· May 2005

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Identification of naturally occurring spirostenols preventing beta-amyloid-induced neurotoxicity.
Laurent Lecanu, Wenguo Yao, Gary L Teper, Zhi-Xing Yao, Janet Greeson

Steroids· January 2004

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Inhibition of adrenal cortical steroid formation by procaine is mediated by reduction of the cAMP-induced 3-hydroxy-3-methylglutaryl-coenzyme A reductase messenger ribonucleic acid levels.
Jing Xu, Laurent Lecanu, Zeqiu Han, Zhixing Yao, Janet Greeson

J Pharmacol Exp Ther· December 2003

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22R-Hydroxycholesterol protects neuronal cells from beta-amyloid-induced cytotoxicity by binding to beta-amyloid peptide.
Zhi-Xing Yao, Rachel C Brown, Gary Teper, Janet Greeson, Vassilios Papadopoulos

J Neurochem· December 2002

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