Publications by authors named "Janet Stavnezer"

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Individual substitution mutations in the AID C terminus that ablate IgH class switch recombination.
Tatenda Kadungure, Anna J Ucher, Erin K Linehan, Carol E Schrader, Janet Stavnezer

PLoS One· May 2016

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Nbs1 ChIP-Seq Identifies Off-Target DNA Double-Strand Breaks Induced by AID in Activated Splenic B Cells.
Lyne Khair, Richard E Baker, Erin K Linehan, Carol E Schrader, Janet Stavnezer

PLoS Genet· August 2015

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Response to comment on "IgH chain class switch recombination: mechanism and regulation".
Janet Stavnezer, Carol E Schrader

J Immunol· March 2015

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IgH chain class switch recombination: mechanism and regulation.
Janet Stavnezer, Carol E Schrader

J Immunol· December 2014

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Crosstalk between BRCA-Fanconi anemia and mismatch repair pathways prevents MSH2-dependent aberrant DNA damage responses.
Min Peng, Jenny Xie, Anna Ucher, Janet Stavnezer, Sharon B Cantor

EMBO J· August 2014

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Mismatch repair proteins and AID activity are required for the dominant negative function of C-terminally deleted AID in class switching.
Anna J Ucher, Sanjay Ranjit, Tatenda Kadungure, Erin K Linehan, Lyne Khair, Janet Stavnezer

J Immunol· August 2014

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Differential expression of APE1 and APE2 in germinal centers promotes error-prone repair and A:T mutations during somatic hypermutation.
Janet Stavnezer, Erin K Linehan, Mikayla R Thompson, Ghaith Habboub, Anna J Ucher

Proc Natl Acad Sci U S A· June 2014

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ATM increases activation-induced cytidine deaminase activity at downstream S regions during class-switch recombination.
Lyne Khair, Jeroen E J Guikema, Erin K Linehan, Anna J Ucher, Niek G J Leus, Janet Stavnezer

J Immunol· May 2014

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DNA polymerases β and λ do not directly affect Ig variable region somatic hypermutation although their absence reduces the frequency of mutations.
Carol E Schrader, Erin K Linehan, Anna J Ucher, Barbara Bertocci, Janet Stavnezer

DNA Repair (Amst)· December 2013

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A DNA break- and phosphorylation-dependent positive feedback loop promotes immunoglobulin class-switch recombination.
Bao Q Vuong, Kayleigh Herrick-Reynolds, Bharat Vaidyanathan, Joseph N Pucella, Anna J Ucher, Janet Stavnezer

Nat Immunol· November 2013

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Activation-induced cytidine deaminase-initiated off-target DNA breaks are detected and resolved during S phase.
Muneer G Hasham, Kathy J Snow, Nina M Donghia, Jane A Branca, Mark D Lessard, Janet Stavnezer

J Immunol· September 2012

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The DNA glycosylases Ogg1 and Nth1 do not contribute to Ig class switching in activated mouse splenic B cells.
Anna J Ucher, Erin K Linehan, George W Teebor, Carol E Schrader, Janet Stavnezer

PLoS One· August 2012

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AID recruits UNG and Msh2 to Ig switch regions dependent upon the AID C terminus [corrected].
Sanjay Ranjit, Lyne Khair, Erin K Linehan, Anna J Ucher, Mrinmay Chakrabarti, Janet Stavnezer

J Immunol· September 2011

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Editorial overview.
Frances Lund, Janet Stavnezer

Curr Opin Immunol· June 2011

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Complex regulation and function of activation-induced cytidine deaminase.
Janet Stavnezer

Trends Immunol· May 2011

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Mapping of switch recombination junctions, a tool for studying DNA repair pathways during immunoglobulin class switching.
Janet Stavnezer, Andrea Björkman, Likun Du, Alberto Cagigi, Qiang Pan-Hammarström

Adv Immunol· January 2011

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Activation-induced cytidine deaminase induces reproducible DNA breaks at many non-Ig Loci in activated B cells.
Ori Staszewski, Richard E Baker, Anna J Ucher, Raygene Martier, Janet Stavnezer

Mol Cell· January 2011

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p53 represses class switch recombination to IgG2a through its antioxidant function.
Jeroen E J Guikema, Carol E Schrader, Michael H Brodsky, Erin K Linehan, Adam Richards, Janet Stavnezer

J Immunol· June 2010

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The role of Apex2 in class-switch recombination of immunoglobulin genes.
Jeroen E J Guikema, Janet Stavnezer, Carol E Schrader

Int Immunol· March 2010

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Class switch recombination efficiency and junction microhomology patterns in Msh2-, Mlh1-, and Exo1-deficient mice depend on the presence of mu switch region tandem repeats.
Jennifer Eccleston, Carol E Schrader, Karen Yuan, Janet Stavnezer, Erik Selsing

J Immunol· July 2009

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The roles of APE1, APE2, DNA polymerase beta and mismatch repair in creating S region DNA breaks during antibody class switch.
Carol E Schrader, Jeroen E J Guikema, Xiaoming Wu, Janet Stavnezer

Philos Trans R Soc Lond B Biol Sci· March 2009

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The surprising discovery that TGF beta specifically induces the IgA class switch.
Janet Stavnezer, Joonsoo Kang

J Immunol· January 2009

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Reassessment of the role of Mut S homolog 5 in Ig class switch recombination shows lack of involvement in cis- and trans-switching.
Jeroen E J Guikema, Carol E Schrader, Niek G J Leus, Anna Ucher, Erin K Linehan, Janet Stavnezer

J Immunol· December 2008

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Mechanism and regulation of class switch recombination.
Janet Stavnezer, Jeroen E J Guikema, Carol E Schrader

Annu Rev Immunol· June 2008

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APE1- and APE2-dependent DNA breaks in immunoglobulin class switch recombination.
Jeroen E J Guikema, Erin K Linehan, Daisuke Tsuchimoto, Yusaku Nakabeppu, Phyllis R Strauss, Janet Stavnezer

J Exp Med· November 2007

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