Publications by authors named "Janin Chandra"

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Spatial analysis of HPV-associated cervical intraepithelial neoplastic tissues demonstrate distinct immune signatures associated with cervical cancer progression.
Gianna Pavilion, Hani Vu, Zherui Xiong, Thi Viet Trinh Dang, Blake O'Brien, Janin Chandra

J Pathol· December 2025

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An α-specific PI3K inhibitor improves chemotherapy efficacy by inhibiting hepatic stellate cell activation in liver cancer.
Qi Ruan, Tao Chen, Minwoo Kim, Haotian Yang, Debottam Sinha, Janin Chandra

Hepatology· December 2025

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The Involvement of IL-34 in Inflammatory and Malignant Skin Diseases.
Thi Viet Trinh Dang, Ahmed M Mehdi, Snehlata Kumari, Kiarash Khosrotehrani, Ian H Frazer, Janin Chandra

J Invest Dermatol· November 2025

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STING Nanoagonist Boosts Antitumor Immunity of Therapeutic DNA Vaccines.
Wencong Jia, Janin Chandra, Siok Min Teoh, Lynn Tolley, Haotian Yang

Nano Lett· December 2024

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Squamous cell carcinoma is associated with reduced IL34 expression, alterations in the Langerhans cell antigen-processing-presentation machinery and poor patient survival.
Thi Viet Trinh Dang, Kevin R Gillinder, Quan Nguyen, Onkar Mulay, Tuan Vo, Janin Chandra

Clin Transl Immunology· November 2024

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A phase Ib study to assess the safety of the human papillomavirus DNA vaccine (AMV002) in combination with durvalumab for HPV-associated oropharyngeal squamous cell carcinoma.
Rahul Ladwa, Janin Chandra, Wai-Ping Woo, Neil Finlayson, Howard Liu

Front Oncol· July 2024

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Characterization of the skin microbiome in normal and cutaneous squamous cell carcinoma affected cats and dogs.
Jacoba I Bromfield, Julian Zaugg, Rodney C Straw, Julia Cathie, Annika Krueger, Janin Chandra

mSphere· April 2024

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HPV status represents dominant trait driving delineation of survival-associated gene co-expression networks in head and neck cancer.
Ahmed M Mehdi, Chenhao Zhou, Gavin Turrell, Euan Walpole, Sandro Porceddu, Janin Chandra

Cancer Gene Ther· April 2023

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Targeting dominated skin dysbiosis in actinic keratosis to prevent the onset of cutaneous squamous cell carcinoma: Outlook for future therapies?
Jacoba Isobella Bromfield, Philip Hugenholtz, Ian Hector Frazer, Kiarash Khosrotehrani, Janin Chandra

Front Oncol· February 2023

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Environmental pathways affecting gene expression (E.PAGE) as an R package to predict gene-environment associations.
Sachin Muralidharan, Sarah Ali, Lilin Yang, Joshua Badshah, Syeda Farah Zahir, Janin Chandra

Sci Rep· November 2022

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Editorial: Cancer Immunotherapies: From Efficacy to Resistance Mechanisms.
Janin Chandra, Morten Hansen, Nathalie Labarriere, Ilaria Marigo, Fernando Souza-Fonseca-Guimaraes

Front Immunol· June 2022

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Acquisition of murine splenic myeloid cells for protein and gene expression profiling by advanced flow cytometry and CITE-seq.
Inga Rødahl, James Gotley, Stacey B Andersen, Meihua Yu, Ahmed M Mehdi, Janin Chandra

STAR Protoc· December 2021

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A model of impaired Langerhans cell maturation associated with HPV induced epithelial hyperplasia.
Zewen K Tuong, Samuel W Lukowski, Quan H Nguyen, Janin Chandra, Chenhao Zhou

iScience· November 2021

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Dysregulation of Stemness Pathways in HPV Mediated Cervical Malignant Transformation Identifies Potential Oncotherapy Targets.
Megha Budhwani, Samuel W Lukowski, Sandro V Porceddu, Ian H Frazer, Janin Chandra

Front Cell Infect Microbiol· June 2021

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Regulatory T Cells but Not IL-10 Impair Cell-Mediated Immunity in Human Papillomavirus E7+ Hyperplastic Epithelium.
Abate Assefa Bashaw, Chenhao Zhou, Meihua Yu, Lynn Tolley, Graham R Leggatt, Janin Chandra

J Invest Dermatol· May 2021

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Absence of Batf3 reveals a new dimension of cell state heterogeneity within conventional dendritic cells.
Samuel W Lukowski, Inga Rødahl, Samuel Kelly, Meihua Yu, James Gotley, Janin Chandra

iScience· May 2021

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Therapeutic DNA Vaccine Against HPV16-Associated Cancer.
Meihua Yu, Janin Chandra

Methods Mol Biol· March 2021

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Manganese-Doped Silica-Based Nanoparticles Promote the Efficacy of Antigen-Specific Immunotherapy.
Janin Chandra, Siok Min Teoh, Paula Kuo, Lynn Tolley, Abate Assefa Bashaw

J Immunol· March 2021

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Immune-Inhibitory Gene Expression is Positively Correlated with Overall Immune Activity and Predicts Increased Survival Probability of Cervical and Head and Neck Cancer Patients.
Megha Budhwani, Gavin Turrell, Meihua Yu, Ian H Frazer, Ahmed M Mehdi, Janin Chandra

Front Mol Biosci· March 2021

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Antigen Nonspecific Induction of Distinct Regulatory T Cell States in Oncogene-Driven Hyperproliferative Skin.
Chenhao Zhou, Zewen Kelvin Tuong, Samuel Wieslaw Lukowski, Janin Chandra, Ian H Frazer

Immunohorizons· February 2021

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Immune responses to a HSV-2 polynucleotide immunotherapy COR-1 in HSV-2 positive subjects: A randomized double blinded phase I/IIa trial.
Janin Chandra, Wai-Ping Woo, Julie L Dutton, Yan Xu, Bo Li

PLoS One· March 2020

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HPV16 E7-Driven Epithelial Hyperplasia Promotes Impaired Antigen Presentation and Regulatory T-Cell Development.
Abate Assefa Bashaw, Siok M Teoh, Zewen K Tuong, Graham R Leggatt, Ian H Frazer, Janin Chandra

J Invest Dermatol· December 2019

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Immunotherapy for HPV associated cancer.
Ian H Frazer, Janin Chandra

Papillomavirus Res· December 2019

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CD8 lineage dendritic cells determine adaptive immune responses to inflammasome activation upon sterile skin injury.
Rituparna Chakraborty, Janin Chandra, Shuai Cui, Lynn Tolley, Matthew A Cooper

Exp Dermatol· January 2018

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Modulation of antigen presenting cell functions during chronic HPV infection.
Abate Assefa Bashaw, Graham R Leggatt, Janin Chandra, Zewen K Tuong, Ian H Frazer

Papillomavirus Res· December 2017

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