Publications by authors named "Janos Groh"

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Single-cell spatial transcriptomic profiling defines a pathogenic inflammatory niche in chronic active multiple sclerosis lesions.
Ruoqing Feng, Lena Spieth, Lu Liu, Stefan Berghoff, Jonas Franz, Janos Groh

Immunity· December 2025

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APOSTEL-R Recommendations for Reporting Retinal Optical Coherence Tomography Studies in Rodents.
Frederike Cosima Oertel, Delia Cabrera Debuc, Peter A Calabresi, Mei Chen, Christian Cordano, Janos Groh

Neurol Neuroimmunol Neuroinflamm· November 2025

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Microglia activation orchestrates CXCL10-mediated CD8 T cell recruitment to promote aging-related white matter degeneration.
Janos Groh, Ruoqing Feng, Xidi Yuan, Lu Liu, Dennis Klein

Nat Neurosci· June 2025

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White matter aging and its impact on brain function.
Janos Groh, Mikael Simons

Neuron· January 2025

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Loss of CLN3 in microglia leads to impaired lipid metabolism and myelin turnover.
Seda Yasa, Elisabeth S Butz, Alessio Colombo, Uma Chandrachud, Luca Montore, Janos Groh

Commun Biol· October 2024

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Clinically approved immunomodulators ameliorate behavioral changes in a mouse model of hereditary spastic paraplegia type 11.
Michaela Hörner, Sandy Popp, Julien Branchu, Giovanni Stevanin, Frédéric Darios, Janos Groh

Front Neurosci· February 2024

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Brain-to-gut trafficking of alpha-synuclein by CD11c cells in a mouse model of Parkinson's disease.
Rhonda L McFleder, Anastasiia Makhotkina, Janos Groh, Ursula Keber, Fabian Imdahl

Nat Commun· November 2023

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Microglia-mediated demyelination protects against CD8 T cell-driven axon degeneration in mice carrying PLP defects.
Janos Groh, Tassnim Abdelwahab, Yogita Kattimani, Michaela Hörner, Silke Loserth

Nat Commun· October 2023

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Cytotoxic CNS-associated T cells drive axon degeneration by targeting perturbed oligodendrocytes in mutant mice.
Tassnim Abdelwahab, David Stadler, Konrad Knöpper, Panagiota Arampatzi, Antoine-Emmanuel Saliba, Janos Groh

iScience· May 2023

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Teriflunomide as a therapeutic means for myelin repair.
Peter Göttle, Janos Groh, Laura Reiche, Joel Gruchot, Nicole Rychlik

J Neuroinflammation· January 2023

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CD8 T cells induce interferon-responsive oligodendrocytes and microglia in white matter aging.
Tuğberk Kaya, Nicola Mattugini, Lu Liu, Hao Ji, Ludovico Cantuti-Castelvetri, Janos Groh

Nat Neurosci· November 2022

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CNS-associated T-lymphocytes in a mouse model of Hereditary Spastic Paraplegia type 11 (SPG11) are therapeutic targets for established immunomodulators.
Michaela Hörner, Janos Groh, Dennis Klein, Winfried Ilg, Ludger Schöls

Exp Neurol· September 2022

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Early targeting of endoneurial macrophages alleviates the neuropathy and affects abnormal Schwann cell differentiation in a mouse model of Charcot-Marie-Tooth 1A.
Dennis Klein, Janos Groh, Xidi Yuan, Kristina Berve, Ruth Stassart

Glia· June 2022

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[Therapeutic accessibility of the retina in systemic immunomodulatory approaches in mouse models for neuronal ceroid lipofuscinosis : Comments on Bartsch et al., Der Ophthalmologe 02/2021].
Rudolf Martini, Thomas Ach, Kevin Rostasy, Janos Groh

Ophthalmologe· July 2021

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Accumulation of cytotoxic T cells in the aged CNS leads to axon degeneration and contributes to cognitive and motor decline.
Janos Groh, Konrad Knöpper, Panagiota Arampatzi, Xidi Yuan, Lena Lößlein

Nat Aging· April 2021

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Immune modulation attenuates infantile neuronal ceroid lipofuscinosis in mice before and after disease onset.
Janos Groh, Kristina Berve, Rudolf Martini

Brain Commun· March 2021

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Sex- and region-biased depletion of microglia/macrophages attenuates CLN1 disease in mice.
Kristina Berve, Brian L West, Rudolf Martini, Janos Groh

J Neuroinflammation· October 2020

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Secretome Analysis of Mesenchymal Stem Cell Factors Fostering Oligodendroglial Differentiation of Neural Stem Cells In Vivo.
Iria Samper Agrelo, Jessica Schira-Heinen, Felix Beyer, Janos Groh, Christine Bütermann

Int J Mol Sci· June 2020

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Heterogeneous fate choice of genetically modulated adult neural stem cells in gray and white matter of the central nervous system.
Felix Beyer, Janusz Jadasz, Iria Samper Agrelo, Jessica Schira-Heinen, Janos Groh

Glia· February 2020

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The CLN3 gene and protein: What we know.
Myriam Mirza, Anna Vainshtein, Alberto DiRonza, Uma Chandrachud, Luke J Haslett, Janos Groh

Mol Genet Genomic Med· December 2019

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Targeting microglia attenuates neuroinflammation-related neural damage in mice carrying human PLP1 mutations.
Janos Groh, Dennis Klein, Kristina Berve, Brian L West, Rudolf Martini

Glia· February 2019

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Teriflunomide attenuates neuroinflammation-related neural damage in mice carrying human PLP1 mutations.
Janos Groh, Michaela Hörner, Rudolf Martini

J Neuroinflammation· July 2018

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Neuroinflammation as modifier of genetically caused neurological disorders of the central nervous system: Understanding pathogenesis and chances for treatment.
Janos Groh, Rudolf Martini

Glia· September 2017

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Fingolimod and Teriflunomide Attenuate Neurodegeneration in Mouse Models of Neuronal Ceroid Lipofuscinosis.
Janos Groh, Kristina Berve, Rudolf Martini

Mol Ther· August 2017

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Pathogenic inflammation in the CNS of mice carrying human PLP1 mutations.
Janos Groh, Hana C Friedman, Nadiya Orel, Chi Wang Ip, Stefan Fischer

Hum Mol Genet· November 2016

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