Publications by authors named "Janusz Stepinski"

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Mammalian Nudt15 hydrolytic and binding activity on methylated guanosine mononucleotides.
Maciej Lukaszewicz, Aleksandra Ferenc-Mrozek, Julia Kokosza, Anna Stefaniuk, Janusz Stepinski

Eur Biophys J· October 2023

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Contribution of Nudt12 enzyme to differentially methylated dinucleotides of 5'RNA cap structure.
Maciej Lukaszewicz, Aleksandra Ferenc-Mrozek, Elzbieta Bojarska, Joanna Stelmach, Janusz Stepinski

Biochim Biophys Acta Gen Subj· September 2023

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Insight into the Binding and Hydrolytic Preferences of hNudt16 Based on Nucleotide Diphosphate Substrates.
Magdalena Chrabąszczewska, Maria Winiewska-Szajewska, Natalia Ostrowska, Elżbieta Bojarska, Janusz Stępiński

Int J Mol Sci· October 2021

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Effect of the His-Tag Location on Decapping Scavenger Enzymes and Their Hydrolytic Activity toward Cap Analogs.
Aleksandra Ferenc-Mrozek, Elzbieta Bojarska, Janusz Stepinski, Edward Darzynkiewicz, Maciej Lukaszewicz

ACS Omega· May 2020

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Hydrolytic activity of human Nudt16 enzyme on dinucleotide cap analogs and short capped oligonucleotides.
Renata Grzela, Karolina Nasilowska, Maciej Lukaszewicz, Michal Tyras, Janusz Stepinski

RNA· May 2018

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Endocardial silicone lead wear: description of tribological phenomena on the basis of microscopic examination of removed leads. Preliminary report.
Barbara Małecka, Andrzej Ząbek, Andrzej Ciaś, Janusz Stępiński, Andrzej Kutarski

Kardiol Pol· December 2016

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Molecular recognition of mRNA 5' cap by 3' poly(A)-specific ribonuclease (PARN) differs from interactions known for other cap-binding proteins.
Anna Niedzwiecka, Per Nilsson, Remigiusz Worch, Janusz Stepinski, Edward Darzynkiewicz

Biochim Biophys Acta· April 2016

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Structural analysis of human 2'-O-ribose methyltransferases involved in mRNA cap structure formation.
Miroslaw Smietanski, Maria Werner, Elzbieta Purta, Katarzyna H Kaminska, Janusz Stepinski

Nat Commun· October 2015

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Effect of different N7 substitution of dinucleotide cap analogs on the hydrolytic susceptibility towards scavenger decapping enzymes (DcpS).
Karolina Piecyk, Zbigniew M Darzynkiewicz, Marzena Jankowska-Anyszka, Aleksandra Ferenc-Mrozek, Janusz Stepinski

Biochem Biophys Res Commun· August 2015

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eIF4F-like complexes formed by cap-binding homolog TbEIF4E5 with TbEIF4G1 or TbEIF4G2 are implicated in post-transcriptional regulation in Trypanosoma brucei.
Eden R Freire, Ajay A Vashisht, Amaranta M Malvezzi, Joanna Zuberek, Gerasimos Langousis, Janusz Stepinski

RNA· August 2014

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7-methylguanosine diphosphate (m(7)GDP) is not hydrolyzed but strongly bound by decapping scavenger (DcpS) enzymes and potently inhibits their activity.
Anna Wypijewska, Elzbieta Bojarska, Maciej Lukaszewicz, Janusz Stepinski, Jacek Jemielity

Biochemistry· October 2012

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Structural basis for nematode eIF4E binding an m(2,2,7)G-Cap and its implications for translation initiation.
Weizhi Liu, Marzena Jankowska-Anyszka, Karolina Piecyk, Laura Dickson, Adam Wallace, Janusz Stepinski

Nucleic Acids Res· November 2011

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Plant nucleoside 5'-phosphoramidate hydrolase; simple purification from yellow lupin (Lupinus luteus) seeds and properties of homogeneous enzyme.
Andrzej Guranowski, Anna M Wojdyła, Anna M Rydzik, Janusz Stepiński, Jacek Jemielity

Acta Biochim Pol· July 2011

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Thermodynamics of molecular recognition of mRNA 5' cap by yeast eukaryotic initiation factor 4E.
Katarzyna Kiraga-Motoszko, Anna Niedzwiecka, Anna Modrak-Wojcik, Janusz Stepinski, Edward Darzynkiewicz

J Phys Chem B· July 2011

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Structural analysis of 5'-mRNA-cap interactions with the human AGO2 MID domain.
Filipp Frank, Marc R Fabian, Janusz Stepinski, Jacek Jemielity, Edward Darzynkiewicz

EMBO Rep· May 2011

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Characterization of hMTr1, a human Cap1 2'-O-ribose methyltransferase.
François Bélanger, Janusz Stepinski, Edward Darzynkiewicz, Jerry Pelletier

J Biol Chem· October 2010

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Structural requirements for Caenorhabditis elegans DcpS substrates based on fluorescence and HPLC enzyme kinetic studies.
Anna Wypijewska, Elzbieta Bojarska, Janusz Stepinski, Marzena Jankowska-Anyszka, Jacek Jemielity

FEBS J· July 2010

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The nematode eukaryotic translation initiation factor 4E/G complex works with a trans-spliced leader stem-loop to enable efficient translation of trimethylguanosine-capped RNAs.
Adam Wallace, Megan E Filbin, Bethany Veo, Craig McFarland, Janusz Stepinski

Mol Cell Biol· April 2010

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Cap analog substrates reveal three clades of cap guanine-N2 methyltransferases with distinct methyl acceptor specificities.
Delphine Benarroch, Marzena Jankowska-Anyszka, Janusz Stepinski, Edward Darzynkiewicz, Stewart Shuman

RNA· January 2010

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Structural insights into parasite eIF4E binding specificity for m7G and m2,2,7G mRNA caps.
Weizhi Liu, Rui Zhao, Craig McFarland, Jeffrey Kieft, Anna Niedzwiecka, Janusz Stepinski

J Biol Chem· November 2009

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Identification of the HIT-45 protein from Trypanosoma brucei as an FHIT protein/dinucleoside triphosphatase: substrate specificity studies on the recombinant and endogenous proteins.
Hiren Banerjee, Jennifer B Palenchar, Maciej Lukaszewicz, Elzbieta Bojarska, Janusz Stepinski

RNA· August 2009

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Diverse role of three tyrosines in binding of the RNA 5' cap to the human nuclear cap binding complex.
Remigiusz Worch, Marzena Jankowska-Anyszka, Anna Niedzwiecka, Janusz Stepinski, Catherine Mazza

J Mol Biol· January 2009

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Synthesis and characterization of mRNA cap analogs containing phosphorothioate substitutions that bind tightly to eIF4E and are resistant to the decapping pyrophosphatase DcpS.
Joanna Kowalska, Magdalena Lewdorowicz, Joanna Zuberek, Ewa Grudzien-Nogalska, Elzbieta Bojarska, Janusz Stepinski

RNA· June 2008

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Affinity of dinucleotide cap analogues for human decapping scavenger (hDcpS).
Zbigniew M Darzynkiewicz, Elzbieta Bojarska, Janusz Stepinski, Jacek Jemielity, Marzena Jankowska-Anyszka

Nucleosides Nucleotides Nucleic Acids· March 2008

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Structural changes of eIF4E upon binding to the mRNA 5' monomethylguanosine and trimethylguanosine Cap.
Izabela Rutkowska-Wlodarczyk, Janusz Stepinski, Michal Dadlez, Edward Darzynkiewicz, Ryszard Stolarski

Biochemistry· March 2008

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